Scientific papers of Hamilton O. Smith, microbiologist and Nobel laureate for his discovery of TypeII restriction enzymes and the sequence of its cleavage sites. He is the co-recipient of the 1978 Nobel Prize in Physiology or Medicine with Werner Arber and Daniel Nathans for the discovery of “restriction enzymes and their application to problems of molecular genetics”. The papers document Smith’s professional career from his appointment at the University of Michigan and Johns Hopkins University to his most recent position as Scientific Director of Synthetic Biology and Bioenergy at the J. Craig Venter Institute. Materials include correspondence, laboratory and research notes, committee appointments, scientific subject files, photographs, and writings by Smith.

17.5 Linear feet (40 manuscript boxes)

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