Background
Alfred Pletscher (1917- ) received his doctorate in Medicine in 1942 and Ph.D. in Chemsitry in 1948, both fro the University
of Zürich. He conducted research at F. Hoffmann-LaRoche, Inc. (Basel, Switzerland and Nutley, New Jersey) and at the University
of Basel. In his curriculum vitae, he identifies his primary scientific activities as: biochemistry and pharmacology of monoamine
(MOA) transmitters in the central nervous system; effect of psychotropic drugs (reserpine, benzoquinolines, phenylethylamines,
MAO-inhibitors, etc.) on cerebral monoamines; relation between cerebral monoamines and behavioral effects of psychotropic
drugs; discovery and development of therapeutically useful drugs , i.e., Madopar (levodopa plus decarboxylase-inhiitors) and
Tetrabenazine; and blood platelets as models for monoaminergic neurons.
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