Alfred Pletscher (1917- ) received his doctorate in Medicine in 1942 and Ph.D. in Chemsitry
in 1948, both fro the University of Zürich. He conducted research at F. Hoffmann-LaRoche,
Inc. (Basel, Switzerland and Nutley, New Jersey) and at the University of Basel. In his
curriculum vitae, he identifies his primary scientific activities as: biochemistry and
pharmacology of monoamine (MOA) transmitters in the central nervous system; effect of
psychotropic drugs (reserpine, benzoquinolines, phenylethylamines, MAO-inhibitors, etc.) on
cerebral monoamines; relation between cerebral monoamines and behavioral effects of
psychotropic drugs; discovery and development of therapeutically useful drugs , i.e.,
Madopar (levodopa plus decarboxylase-inhiitors) and Tetrabenazine; and blood platelets as
models for monoaminergic neurons.
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