Papers of Daniel Koshland, pioneering biochemist and former faculty at the University of California, Berkeley.
Daniel E. Koshland, Jr. (1920-2007), pioneering biochemist, was educated at the University of California and the University
of Chicago. While in Chicago, Koshland worked on the Manhattan Project as part of a team that successfully purified plutonium.
In 1965, Koshland joined the Biochemistry faculty at the University of California, Berkeley. In 1966, Koshland published what
would become a classic paper, "Comparison of experimental binding data and theoretical models in proteins containing subunits."
In the 1970s, Koshland's lab moved its focus to exploring bacterial chemotaxis. In 1984, he and Albert Goldbeter introduced
the concept of "ultrasensitivity." In addition, Koshland was an active administrator on campus, serving as chair of the biochemistry
department in the mid-1970s and instituting a reorganization of the campus' biology faculty in the 1980s. In 1985, Koshland
was appointed editor of Science Magazine, a post he retained until the mid-1990s. Koshland was married to Marian (Bunny) Koshland,
also an accomplished scientist. Koshland and his wife were active philanthropists for science. As one of the heirs to the
Levi Strauss fortune, Koshland helped finance science buildings on the UC Berkeley campus as well as at Haverford College.
Koshland also endowed and helped design the Marian Koshland Science Museum in Washington, D.C.
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