American Association of Clinical Chemists Award 1976

American Institute of Chemists - certificate of membership 1969

American Men of Science - biographical information 1967

Appointment book 1983

Appointment book 1984

Association memberships - miscellaneous 1962 - 1985

Charitable contributions and misc. financial records 1974 - 1984

Condolences on the death of Nathan Kaplan 1986

Curriculum vitae and miscellaneous biographical information 1960 - 1970

Guggenheim Fellowship award 1975

Leaders in American Science - biographical data sheet, n.d.

Personnel files - academic and admin. appts., merit increases, retirement 1969 - 1975

Photographs of Nathan Kaplan, n.d.

Photographs of Nathan Kaplan's colleagues and mentors, 1982 and n.d.

Proteins and Nucleic Acids symposium - photograph

Who's Who - biographical information 1960 - 1970

Administrative and general information 1968 - 1976

Association of Brandeis biochemists 1979 - 1981

Commencement - May 23, 1982 and symposium in honor of Kaplan - May 25, 1982

Department of biochemistry - adjunct professorship 1968 - 1969

Department of biochemistry - student rotation papers and lab reports 1963

Department of biochemistry - student rotation papers and lab reports 1965

Department of biochemistry - student rotation papers and lab reports 1966

Department of biochemistry - student rotation papers and lab reports 1966 - 1967

Department of biochemistry - student rotation papers and lab reports 1966 - 1967

Department of biochemistry - student rotation papers and lab reports 1966 - 1967

Department of biochemistry - student rotation papers and lab reports 1967 - 1968

Pediatric pharmacology conference - Washington, DC 1967

Eighth International Congress of Biochemistry - Interlaken, Switzerland 1970

Harvey Society lecture - New York City, N.Y. 1971

Thirteenth Science Writers' Seminar of the American Cancer Society - Phoenix, AZ 1971

Enzyme engineering conference, Engineering Foundation - Henniker, NH 1971

Tenth International Symposium on Regulation of Enzyme Activity... 1971

Cellular control mechanisms lecture - Univ. of North Carolina, Chapel Hill, NC 1971

American Cancer Society, Second Annual Combined Meeting on Research 1972

Federation of European Biochemical Societies Eighth Meeting 1972

California State University, Fullerton, department of chemistry seminar 1973

Third Pharmacology - Toxicology Program Symposium, Nat'l Instit of Gen Med Sci 1973

Enzyme engineering conference, Engineering Foundation - Henniker, NH 1973

Physical biology seminar series - Pomona College, Claremont, CA 1974

Symposium on Polymer Grafts in Biochemistry, American Chemical Society 1974

Meetings with Dean Wagner and V.P. Kaprielian, University of Southern California 1974

Biochemistry/Biophysics meeting, American Society of Biological Chemists 1974

Conference on Enzyme Engineering - University of California, San Diego 1974

NSF/RANN Grantees conference, National Science Foundation - Washington, D.C. 1974

Dexter Goldman of Makor Chemicals Ltd. , Jerusalem - visit to UCSD 1974

D. M. Updegraff of Cawthron Institute, New Zealand - visit to UCSD 1974

University of Texas at Austin seminar, department of chemistry 1975

Amer. Instit. of Chemical Engineers, Seventy-ninth Nat'l Meeting - Houston, TX 1975

Michigan State University seminar, department of biochemistry - East Lansing, MI 1975

Hugo Thorell, Nobel Prize winner - visit to UCSD 1975

Federation of American Societies for Experimental Biology Annual Meeting 1975

International Symposium on Analysis and Control of Immobilized Enzyme Systems 1975

Chinese molecular biology group - visit to UCSD 1975

NSF/RANN Grantees Conference on Enzyme Technology; did not attend 1975

Sixth International Congress for Pharmacology, Int'l Union of Pharmacology 1975

Engineering Foundation conference - Reed College, Portland, OR 1975

Symposium on Chemistry and Applications of Coenzymes and Coenzyme Analogs 1975

Amoco Research Center lecture - Naperville, IL 1975

Amer. Instit. of Chem. Engineers, Sixty-eighth Annual Meeting - Los Angeles, CA 1975

Eighth Miami Winter Symposium, "Proteolysis and Physiological Regulation" and... 1976

Armand Hammer Symposium on Tumor Biology, Salk Institute - San Diego, CA 1976

Oak Ridge National Laboratory lecture - Oak Ridge, TN 1976

Federation of Amer. Societies for Experimental Biology, Sixtieth Annual Meeting 1976

Onco-Developmental Gene Expression Conference 1976

UNEP/UNESCO/ICRO-IFIAS Symposium - Orsundsbro, Sweden 1976

US/USSR Joint Seminar on Enzyme Technology - Corning, NY 1976

Int'l Symposium on Polymeric Delivery Systems, Midland Macromolecular Instit. 1976

Molecular Structural Meth. in Biological Research Conf., Stanford Mag. Res. Lab 1976

Symposium in honor of Carl F. Cori, University of Washington - St. Louis, MO 1976

Sixty-ninth Annual Meeting, American Institute of Chemical Engineers,... 1976

Johns Hopkins University lecture - Baltimore, MD 1976

Louisiana Board of Regents, site visits 1977

Louisiana Board of Regents, site visits 1977

International Symposium on the Molecular Basis of Cell - Cell Interaction 1977

Texas Technical University, School of Medicine lecture - Lubbock, TX 1977

Symposium on the Use of Athymic Mice in Cancer Research 1977

Fifth American Peptide Symposium - University of California, San Diego 1977

Spanish Biomedical Society Meeting, Universidad de Navarra - Pomplona, Spain 1977

Third Annual Conference on Molecular Structural Methods in Biological Research 1977

American Society for Cell Biology, Seventeenth Annual Meeting - San Diego, CA 1977

Nat'l Instit. of Environmental Health Sciences, Meeting on Prog. Development... 1977

La Jolla Symposium on Biological Applications of NMR Spectroscopy - UCSD 1978

Drug Carriers in Biology and Medicine, Gordon Research Conference 1978

Nat'l. Instit. of Environmental Health Sciences, Meeting on Biochemical... 1978

Immobilized Enzymes, Complexes, and Cells, Gordon Research Conference 1978

Workshop on Hydrogenases: Their Structure, Function, Localization and Distrib. 1978

US/USSR Scientific Exchange on Reaction Catalyzed by Microbiol Enzymes 1978

History and Significance of Isoenzymes lecture, UC Irvine, College of Medicine 1978

Sixth Enzyme Mechanisms Conference - La Jolla, CA 1979

Struct.-Funct. Characteristics of Pyridine Nucleotide Transhydrogenase lecture 1979

Third Annual Symposium, Enzyme Club lecture - Univ. of N. Carolina, Chapel Hill 1979

Kansas Academy of Science, Annual Meeting, Witchita State Univ. - Witchita, KS 1979

Federation of American Societies of Experimental Biology - Dallas, TX 1979

Oscar Bodansky Tribute Symposium, Memorial Sloan-Kettering Cancer Center 1979

Chemotherapy of Experimental and Clinical Cancer, Gordon Research Conference 1979

Concepts of Chemical Recognition Biology Symposium 1979

International CNRS Symposium on Immobilized Enzymes, Organelles and Cells:... 1979

Fifth Engineering Foundation Conference on Enzyme Engineering - Henniker, NH 1979

Third International Workshop on Nude Mice, Montana State Univ. - Bozeman, MT 1979

Novel ADP - Ribosylations of Regulatory Enzymes and Proteins Conference 1979

Modulation of Cellular Interactions of Vitamin A and Derivatives 1980

Eleanor Roosevelt Institute for Cancer Research, Inc. Seminar 1980

Watkins Visiting Professor, Wichita State University - Wichita, KS 1980

American Institute of Nutrition Meeting - Anaheim, CA 1980

American Association for Cancer Research Annual Meeting - San Diego, CA 1980

American Society of Biological Chemists, Seventy-First Annual Meeting 1980

Recent Developments in Anthracycline Chemotherapy Seminar 1980

Pacific Slope Biochemical Conference - University of California, San Diego 1980

Meeting with Arthur Robinson, co-editor of "From Cyclotrons to Cytochromes" 1980

Third Annual Bristol-Myers Symposium on Cancer Research Advances in Malignant... 1980

Tumor Viruses and Differentiation mini-symposium, UCLA Molecular Biology Instit. 1980

Thirteenth Miami Winter Symposium, "Cellular Responses to Molecular Modulators" 1981

Amer. Assoc. for Cancer Research, Seventy-Second Annual Meeting - Washington, DC 1981

Symposium on Enzyme Regulation in Sidney Colowick's Honor, Vanderbilt Univ. 1981

Amer. Soc. of Biological Chemists, Seventy-Second Annual Meeting - St. Louis, MO 1981

David Shemin Celebration, Northwestern University - Evanston, IL 1981

Twelfth International Congress of Chemotherapy - Florence , Italy 1981

Eastman Kodak visit, Biosciences Division - Rochester, NY 1981

Medicine in Transition Symposium 1981

Harvard Medical School seminar, dept. of biochemistry - Cambridge, MA 1981

Fourteenth Miami Winter Symposium, "From Gene to Protein: Translation into... 1982

Chemistry and Biology of Interferons - Relationship to Therapeutics Seminar 1982

Tumor Viruses and Differentiation Seminar - Squaw Valley, CA 1982

Lester Krampitz lecture, Case Western Reserve University - Cleveland, OH 1982

Federation of Amer. Soc. for Experimental Biology, Sixty-sixth Annual Meeting 1982

Professor I.C. Gunsalus Symposium, University of Illinois at Urbana-Champaign 1982

Merton F. Utter Memorial Symp., Case Western Reserve Univ., School of Medicine 1982

Mellon Workshop, Vanderbilt University, School of Medicine - Nashville, TN 1982

Fourth International Congress on Isozymes, University of Texas at Austin 1982

Thirteenth International Cancer Congress - Seattle, Washington 1982

Fourth Int'l. Workshop on Immune-Deficient Animals - Lousanne, Switzerland 1982

Hybritech Inc. Scientific Board of Advisors, Second Annual Meeting 1982

American Association for Cancer Research, Annual Meeting - San Diego, CA 1983

American Society of Biological Chemists Meeting - San Francisco, CA 1983

Fifth International Symp. on Affinity Chromatography and Biological Recognition 1983

Britton Chance's Seventieth Birthday Celebration - Philadelphia, PA 1983

Nat'l. Res. Council, Committee on Biotechnology Applied to Naval Needs Workshop 1983

Molecular Biosystems, Inc., Board of Scientific Advisors Meeting - San Diego, CA 1984

Second Int'l. Congress on Myocardial and Cellular Bioenergetics & Compartmentati 1984

International Symposium on the Molecular Basis of Cellular Regulation 1984

Third Lipmann Symposium - Okazaki, Japan; did not attend 1984

Helicon Symposium, Nutrition and Disease: Cancer - San Diego, CA 1984

Hybritech Inc., Board of Scientific Advisors meeting - San Diego, CA 1984

Symposium on Cancer Chemosensitivity Assays, Long Beach Community Hospital 1984

Meeting with Academic Press representatives - Orlando, FL 1984

Leukemia Symposium, UCLA, Molecular and Cellular Biology Series - Keystone, CO 1985

Ninth Enzyme Mechanisms Conference - Tarpon Springs, FL 1985

Federation of Amer. Soc. for Experimental Biology, Sixty-ninth Annual Meeting 1985

Meeting with Shirley Light, Academic Press editor - Anaheim, CA 1985

Symposium Honoring Samuel P. Bessman, USC, School of Medicine - Los Angeles, CA 1985

National Academy of Sciences, One Hundred Twenty-second Annual Meeting 1985

Spanish Society of Biochemistry, Twelfth Meeting - Valencia, Spain 1985

David Greenberg's Ninetieth Birthday Celebration, Univ. of Calif. San Francisco 1985

Sixth International Symposium on Bioaffinity Chromatography Related Technologies 1985

Proposed visit to Shanghai Institute of Biochemistry - Shanghai, China 1985

Perspectives in Medical Biochemistry Symposium - Kobe, Japan 1985

Sidney Cohen Symposium, Brandeis University - Waltham, MA 1986

National Academy of Sciences, One Hundred Twenty-third Annual Meeting 1986

Symposium in Honor of Ephraim Katzir - Rehovoth and Tel-Aviv, Israel 1986

Joint Meeting, Amer. Soc. of Bio. Chem. and Div. of Bio. Chem. of Amer. Chem. So 1986

1957-1969

1970 (Jan. 14 - Sept. 30)

1970 (Oct. 5 - Dec. 22)

1971 (Jan. 4 - May 28)

1971 (June 3 - Sept. 30)

1971 (Oct. 1 - Dec. 30)

1972 (Jan. 6 - March 31)

1972 (April 4 - June 8)

1972 (July 5 - Dec. 27)

1973 (Jan. 2 - March 30)

1973 (April 2 - June 29)

1973 (July 2 - Sept. 28)

1973 (Oct. 1 - Dec. 20)

1974 (Jan. 2 - Feb. 28)

1974 (March 4 - April 29)

1974 (May 1 - June 28)

1974 (July 1 - Aug. 30)

1974 (Sept. 2 - Dec. 31)

1975 (Jan. 2 - Feb. 28)

1975 (March 7 - April 30)

1975 (May 1 - Aug. 29)

1975 (Sept. 5 - Dec. 30)

1976 (Jan. 6 - April 22)

1976 (May 4 - July 30)

1976 (Aug. 3 - Dec. 30)

1977 (Jan. 4 - April 29)

1977 (May 2 - Aug. 29)

1977 (Sept. 2 - Dec. 19)

1978 (Jan. 3 - May 31)

1978 (June 1 - Dec. 22)

1979 (Jan. 10 - May 24)

1979 (June 4 - Dec. 21)

1980 (Jan. 2 - May 30)

1980 (June 17 - Dec. 23)

1981 (Jan. 9 - May 29)

1981 (June 9 - Dec. 11)

1982 (Jan. 8 - Dec. 22)

1983 (Jan. 11 - Dec. 21)

1984 (Jan. 4 - Dec. 13)

1985 (Jan. 25 - Nov. 13)

1986 (March 14 - April 10)

Undated

Abe, Vivian - Arnold, Lyle

Ashani, Yacov - Barron, Alan

Bartch, Robert - Bock, Paul

Bohlen, Peter - Byfield, John

Burton, Robert - Caplan, Arnold

Caplow, Arnold - Chin, Der-Hang

Chytil, Frank - Colowick, Sidney

Comprehensive Biochemistry - Czerlinski, George

Czerkinski, George - Dickerman, Herbert

Dickinson, David - Elsevier Publishing Company

Eppenberger, Hans - Feldstein, Janice

Felix, Rolf - Frei, Emil

Friedkin, Morris - Goodman, Murray

Goodfriend, Theodore - Holmes, Roger

Horecker, B. L. - Isler, Rosina

Itiaba, Kibe - Katchalski (Katzir), Ephraim

Katzenstein, David - Kochakian, C. D.

Kodansha, Ltd. - Lee, Chi-Yu (Gregory)

Lee, Chi-Yu (Gregory) - Levin, Yehuda

Levine, Lawrence - Louderback, Allan

Louie, Daniel - Masters, Colin

Masui, Hideo - Miyairi, Sachio

Moldave, Kivie - Nason, Alvin

National Academy of Sciences - Owashi, Leslie

Parola, Abraham - Raszka, Matthew

Raw, Isaias - Saiki, Takashi

Salthe, Stanley - Shafer, Richard

Shalitin, Yechiel - Sirbasku, David

Smith, J. Graham - Swislocki, Norbert

Sy, Jose - Venter, Barbara R.

Venter, Craig - West, Brian

White, Hal - Widmer, Francois

Wishnow, Rodney - Yashphe, Jacob

Yeh, Yun-Chi - Zuckerman, J.J.

Unidentified/unidentifiable

AB Experiment to test the effect of antimelanoma serum 1979

Affinity ligands and dyes 1983

American Academy of Arts and Sciences (1973; 1983-84)

Amer. Cancer Society - advisory committee on biochem. and chem. carcinogenesis 1976 - 1980

American Chemical Society - Division of Biological Chemistry 1980

American Chemical Society - Division of Biological Chemistry (1 of 2 folders) 1981

American Chemical Society - Division of Biological Chemistry (2 of 2 folders) 1981

American Chemical Society - Division of Biological Chemistry 1982

American Chemical Society - Division of Biological Chemistry (1 of 2 folders) 1983

American Chemical Society - Division of Biological Chemistry (2 of 2 folders) 1983

American Chemical Society - Division of Biological Chemistry (1 of 2 folders) 1984

American Chemical Society - Division of Biological Chemistry (2 of 2 folders) 1984

American Chemical Society - Division of Biological Chemistry 1985

American Chemical Society - Eli Lilly and Pfizer Award Ballots 1981

American Chemical Society - Eli Lilly and Pfizer Award Nominations 1980 - 1981

American Institute of Nutrition 1977 - 1978

American Instrument Company, 1974 and 1977

American Society of Biological Chemists - general info., 1972-73 and 1981-84

American Society of Biological Chemists - nominations 1970 - 1984

American Society of Biological Chemists - Publications Committee 1976 - 1979

Amer. Soc. of Bio. Chemists - Publications Committee Meeting, New Orleans, LA

Amer. Soc. of Bio. Chemists - Publications Committee, Recombinant Problem 1980 - 1981

Amino Acids - methods for arriving at "code words" 1967 - 1968

Academic Press - "Analytical Biochemistry", budget account 1985 - 1986

APDPN assay data, n.d.

Biochemical Anthropology - funding proposal to the Commonwealth Fund 1970 - 1972

Biochemical Anthropology - draft chapter on Jewish community and research materi 1972

Biotechnology resource prog. in biological microcalorimetry and thermochemistry 1980 - 1981

Biotechnology resource prog. in biological microcalorimetry and thermochemistry 1980 - 1981

Burkitt's Lymphoma, n.d.

Cancerous tumors - charts and write-ups , n.d.

Cancers (colon, breast, misc.) - original graphs, n.d.

Carbohydrate and coenzyme diagrams, n.d.

Catecholamine assay 1976

Check requests for miscellaneous expenses 1976 - 1983

Chemical compounds - models and tables, n.d.

Chemical compounds - Roche data 1976 - 1978

Chemico-Biological Interactions - journal editorial board 1968 - 1969

Chemotherapy - miscellaneous handwritten notes, n.d.

Chemotherapeutic studies 1977 - 1981

Citric acid cycle - diagram, n.d.

Coenzyme distribution - photoprints of tables and figures and misc. graphs, n.d.

Colowick, Sidney (1976; 1985)

Commercial clinical laboratories - list of names and addresses 1973

Consejo Cultural Mundial - Albert Einstein Award, ballots and miscellaneous 1982 - 1984

Enzymes - prints of models, n.d.

Ferredoxins, hydrogenases and metabolic pathways - diagrams, n.d.

Fogarty scholar in residence 1984

Harvard Med. School - commission report on relat. with Black community in Boston 1969

High-pressure liquid chromatology - products manufactured by Kontron Analytical 1982

Hoffman-La Roche Inc. 1976 - 1980

Interferon research 1979 - 1981

Interferon research - Academic Press, laboratory data 1980

Interferon research - Kroc grant proposal 1978

Interferon research - Slimmer, Sheryl, laboratory data 1979

Interferon results - Rene 1982

International Federation of Institutes for Advanced Study 1973 - 1974

International Union of Biochemistry 1983 - 1985

Int'l. Union of Biochem. - interest group on bioaffinity principles and methods 1984

International Sponsoring Committee - Chaim Weizmann centenary celebration 1974

Jewish settlements, history - miscellaneous handwritten notes, 1970's(?)

Johns Hopkins University - proposal for program in medicine and human biology 1971

Journal of Applied Biochemistry, 1981; 1984-85

Journal subscriptions 1974 - 1984

Kamen Symposium - administrative and financial data 1978 - 1982

Kamen Symposium - background materials on Kamen's scientific contributions 1940 - 1970

Kamen Symposium - financial materials related to publication of symp. manuscript

Kamen Symposium - funding and administrative arrangements 1976 - 1978

Kamen Symposium - Kettering Foundation funding 1976 - 1978

Kamen Symposium - letters and invitations; address lists

Kamen Symposium - National Science Foundation grant 1978 - 1979

Kamen Symposium - travel expenses/reimbursements

Laboratory apparatus - drawing, n.d.

Lactate acid papers, n.d.

La Jolla Cancer Research Foundation 1976 - 1978

La Jolla Cancer Research Foundation - board of scientific advisors 1978 - 1980

La Jolla Cancer Research Foundation - site visit 1977

Lecture notes - acyl transfer (handwritten) 1965

Lecture notes - ascorbic acid (typed) n.d.

Lecture notes - biochemical anthropology (handwritten) n.d.

Lecture notes - biotin (typed) n.d.

Lecture notes - cellular regulation (handwritten) n.d.

Lecture notes - chemotherapy (handwritten) n.d.

Lecture notes - choline esterases (handwritten) n.d.

Lecture notes - enzyme mechanisms (handwritten) n.d.

Lecture notes - elementary nutrition (handwritten) n.d.

Lecture notes - elementary vitamins (handwritten) n.d.

Lecture notes - fat soluble vitamins, A and D (typed) n.d.

Lecture notes - fatty acid oxidation (handwritten) n.d.

Lecture notes - fatty acids (handwritten) n.d.

Lecture notes - ferredoxins (handwritten) n.d.

Lecture notes - fluorescence (handwritten) n.d.

Lecture notes - folic acid (typed) n.d.

Lecture notes - glycolysis (typed) n.d.

Lecture notes - hormones (handwritten) n.d.

Lecture notes - inositol (typed) n.d.

Lecture notes - Kreb's cycle (typed) n.d.

Lecture notes - list of lecture titles

Lecture notes - miscellaneous, n.d.

Lecture notes - neurochemistry (handwritten) n.d.

Lecture notes - nucleic acids (typed) n.d.

Lecture notes - nutrition (handwritten) n.d.

Lecture notes - oxidative generation of energy-rich phosphate bonds (typed) n.d

Lecture notes - oxidative phosphorylation (handwritten) n.d.

Lecture notes - pantothenic acid (typed) n.d.

Lecture notes - para-aminobenzoic acid (typed)

Lecture notes - pyruvate kinase (typed) n.d.

Lecture notes - pyruvic and acetic acid metabolism (typed) n.d.

Lecture notes - riboflavin (typed) n.d.

Lecture notes - subunits (handwritten) n.d.

Lecture notes - thiamin (typed) n.d.

Lecture notes - vitamin B6 group (typed) n.d.

Lecture notes - vitamins (handwritten) n.d.

Lecture notes (old) - vitamins (handwritten) n.d.

Mannitol dehydrogenase - typescript, no author, n.d.

Massachusetts Instit. of Tech. - Corp. Visiting Committee for dept. of biology 1978 - 1984

Massachusetts Instit. of Tech. - Corp. Visiting Committee for dept. of biology 1978 - 1984

McElroy, William - Chancellor, UCSD, 1971; 1977-79

Mount Sinai School of Medicine - Kaplan's appt. as visiting adjunct professor 1975 - 1976

National Academy of Sciences 1970 - 1985

National Academy of Sciences - manuscripts sent to Proc. of Nat'l Acad. of Sci. 1971 - 1986

N. A. S. - Nat'l. Research Council, Board on Chemical Sciences and Technology 1985

N. A. S. - Nat'l. Research Council, Office of Biochemical Nomenclature 1975 - 1979

N. A. S. - Nat'l. Research Council, International Union of Biochemists 1981 - 1983

N. A. S. - Nat'l. Research Council, International Union of Biochemists 1981 - 1983

N. A. S. - Nat'l. Research Council, International Union of Biochemists 1983

National Academy of Sciences - nomination of John Abelson 1981 - 1983

National Academy of Sciences - nomination of Morris Friedkin 1977 - 1978

National Academy of Sciences - nomination of Dr. Joseph Kraut 1985 - 1986

National Academy of Sciences - nomination, miscellaneous

National Academy of Sciences - nomination for San Pietro 1977 - 1979

National Academy of Sciences - site visit 1971

National Science Foundation - funding science research 1970 - 1975

Notes - misc. handwritten notes on work by Elford, Harris and others, n.d.

Oak Ridge National Laboratory - advisory committee for biology 1975 - 1976

Oak Ridge National Laboratory - report of visiting committee 1976

Oncogenes - reports on human oncogenes 1984

Orloff, Marshall - investigation of alleged unauthorized medical services 1977

Osteoclast activating factors - application for funding 1977

Oxalate inhibition of lactic dehydrogenases data, n.d.

Patent - Method for reducing the toxicity of 6-aminonic-otinamide 1982

Patent - miscellaneous 1975 - 1976

Patent - Synthetic polymeric derivatives of catecholamines 1975 - 1976

Patent - Well-characterized oligopeptide leashes for small biologically... 1976

Pharmacology-B study section 1969

Postdoctoral fellows and graduate students - list of most recent 1972

Publications of staff - lists from McCollum-Pratt and Brandeis 1950 - 1960

Pyridine chemistry review and photographs models of DPN chemical structure, n.d.

Pyridine protons data - Foster-Miller, Inc., n.d.

Reprint requests 1975

Research proposal - Engineering thermophilic microorganisms to convert... 1980

Research proposal - Exchange rates of oxygen and CO2 at capillary interfaces

Research proposal - miscellaneous (1970's)

Research proposal - Transportable human tumor lines 1974

San Diego County Heart Association 1969

Scripps Memorial Hospital - Human Use Committee 1981 - 1983

Scripps Memorial Hospital - Human Use Committee, meeting May 5, 1982

Scripps Memorial Hospital - Investigation Review Committee 1977 - 1980

Slides - master copies of figures and tables 1964 - 1965

Tables, graphs, data sheets and other miscellaneous material, n.d.

Talks given by Kaplan group 1971 - 1980

Travenol Laboratories, Inc. - research agreement with UCSD Foundation 1973 - 1979

Tumor activity data - tables and data on human tumors, n.d.

Unitika Ltd. - enzyme research and development with Technicon Instruments Corp. 1980 - 1981

University of California, Berkeley - review of Graduate Division of Chemistry 1976

Univ. of Chicago - Argonne Cancer Research Hospital, advisory review committee 1969

Univ. of Chicago - Argonne Cancer Research Hospital, advisory review committee

Univ. of Chicago - Argonne Cancer Research Hospital, advisory review committee 1970

Univ. of Chicago - Franklin McLean Memorial Research Instit., advisory committee 1973

Univ. of Pennsylvania - grad. group in molecular bio., external review committee

Wichita State Univ. - Biochemistry Review Team, site visit, Nov. 18-20, 1976

Japan, Korea, India sabbatical, June - July 1970

Israel and Europe sabbatical, June - August 1975

Israel and Stockholm, Sweden, June - July 1976

Miscellaneous travel 1977 - 1984

Madrid, Spain - Institute de Catalisis y Petroleoquimica, June - July 1979

China - Shanghai Institute of Biochemistry, Sept. 1979

China - Shanghai Institute of Biochemistry, reprints in Chinese, Sept. 1979

China - Shanghai Institute of Biochemistry, reprints in Chinese, Sept. 1979

Japan, Aug. 1979

Milan, Italy and Madrid, Spain, April 1981

Japan, July 1981

Spain and Israel sabbatical, March - April 1982

Academic Senate - committee on research, 1968-70; 1974

Athymic Mouse Facility - administrative and general information 1973 - 1975

Athymic Mouse Facility - administrative and general information 1978 - 1981

Athymic Mouse Facility - administrative and general information 1983

Athymic Mouse Facility - administrative and general information 1984

Athymic Mouse Facility - animal use report 1977 - 1983

Athymic Mouse Facility - construction/repair requests and miscellaneous 1983 - 1984

Athymic Mouse Facility - construction of work space for Dr. Martin Haas 1982

Athymic Mouse Facility - environmental health and safety reports 1979 - 1981

Athymic Mouse Facility - Executive Committee 1980 - 1982

Athymic Mouse Facility - fire, October 1980

Athymic Mouse Facility - grant proposal to Amerian Cancer Society 1980

Athymic Mouse Facility - grant proposal to Amerian Cancer Society 1980

Athymic Mouse Facility - grant proposal to Amerian Cancer Society 1980

Athymic Mouse Facility - grant proposal to Amerian Cancer Society 1980

Athymic Mouse Facility - proposed funding 1980 - 1981

Athymic Mouse Facility - recruitment, assistant adjunct professor 1981

Athymic Mouse Facility - recruitment, general information 1982 - 1983

Athymic Mouse Facility - recruitment, pathologist 1982

Athymic Mouse Facility - recruitment, potential new personnel/visitors 1981

Athymic Mouse Facility - recruitment, staff research associate III 1982

Athymic Mouse Facility - research seminar announcements 1979

Athymic Mouse Facility - site visit agenda, March 6, 1984

Athymic Mouse Facility - site visit miscellaneous material, Aug. 16, 1981

Athymic Mouse Facility - users of nude mice 1978 - 1982

Biomed. studies advisory committee; faculty advisory committee; and misc. 1968 - 1971

Building advisory committee for building 2B/2B' 1969 - 1971

Cancer Center - administrative 1978 - 1981

Cancer Center - administrative 1982

Cancer Center - administrative 1983 - 1984

Cancer Center - Basic Sciences Advisory Committee, minutes 1981 - 1982

Cancer Center - Cancer Cell Facility floor plan, n.d.

Cancer Center - Clinical Sciences Advisory Committee, minutes 1981

Cancer Center - dedication of Theodore Gildred Cancer Facility, April 15, 1983

Cancer Center - financial records, Brunswick Foundation grant 1984 - 1985

Cancer Center - financial records, coenzyme and acid metabolism research grant 1984 - 1985

Cancer Center - financial records, Farmitalia Carlo Erba 1984 - 1986

Cancer Center - financial records, miscellaneous 1982 - 1983

Cancer Center - financial records, miscellaneous 1984 - 1985

Cancer Center - financial records, Monsanto Co. grant to study tumor antigens 1984 - 1985

Cancer Center - Internal Advisory Committee; memos and meeting minutes 1978 - 1982

Cancer Center - personnel information 1978 - 1982

Cancer Center - retreat, January 15-19, 1982

Chem. Dept. - academic support allocations, faculty positions, FTE allotments 1969 - 1972

Chemistry Department - administrative 1968 - 1972

Chemistry Department - administrative 1974

Chemistry Department - administrative 1976 - 1982

Chemistry Department - administrative 1983

Chemistry Department - administrative 1984

Chem. Dept. - Biomed. Library policy; impact on undergrads. in biochem. courses 1972

Chem. Dept. - candidate for faculty position: DeLuca, Marlene 1974

Chem. Dept. - candidate for faculty position: Singh, Sarjant, n.d.

Chem. Dept. - candidate for faculty position: Seegmiller, Jarvis, n.d.

Chem. Dept. - candidate for faculty position: Valentine, Ray, n.d.

Chem. Dept. - candidate for faculty position: Wolf, Alfred 1972

Chem. Dept. : Courses - Advanced Biochemistry (Biochem 103 - History of Biochem 1968 - 1969

Chem. Dept. : Courses - Advanced Biochem handouts (Bio 118/218, Chem 118/218) 1971

Chem. Dept. : Courses - Advanced Biochem handouts (Bio 118/218, Chem 118/218) 1972

Chem. Dept. : Courses - Advanced Biochemistry handouts (Chem 118/218) 1972

Chem. Dept. : Courses - Advanced Biochemistry handouts (Biochem 118/218) 1973

Chem. Dept. : Courses - Advanced Biochemistry handouts (Chem/Bio 218) 1974

Chem. Dept. : Courses - Biochemical Anthropology course readings, n.d.

Chem. Dept. : Courses - Biochemistry 101a,b diagrams, 1960's and n.d.

Chem. Dept. : Courses - Biochemistry exams 1967 - 1971

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1968

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1969

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1969

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1970

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1970

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1971

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1972

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1973

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1973

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1974

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1974

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1975

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1980

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1982

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1983

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1984

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1984

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1984

Chem. Dept. : Courses - Cell Biology and Biochemistry (CBB) 1984

Chem. Dept. : Courses - Chemistry 210, M.D. Kamen seminar 1973

Chem. Dept. : Courses - Frontiers of Science 1971

Chem. Dept. : Courses - Frontiers of Science 1971

Chem. Dept. : Courses - Frontiers of Science 1972

Chem. Dept. : Courses - Frontiers of Science 1972

Chem. Dept. : Courses - Frontiers of Science 1972

Chem. Dept. : Courses - Frontiers of Science 1977

Chem. Dept. : Courses - Frontiers of Science 1977

Chem. Dept. : Courses - Frontiers of Science 1977

Chem. Dept. : Courses - Frontiers of Science 1983

Chem. Dept. : Courses - Frontiers of Science 1985 - 1986

Chem. Dept. : Courses - Frontiers of Science 1985 - 1986

Chem. Dept. : Courses - History of Biochemistry 214 1980

Chem. Dept. : Courses - History of Biochemistry 214 1982

Chem. Dept. : Courses - Human and Introductory Biochem. (1 of 2 folders) 1972

Chem. Dept. : Courses - Human and Introductory Biochem. (2 of 2 folders) 1972

Chem. Dept. : Courses - Human Biochemical Evolution (Bio 240) 1973

Chem. Dept. : Courses - Human Biochemistry (Bio 217/Chem 217) 1971

Chem. Dept. : Courses - Human Biochemistry (Bio 217/Chem 217) 1971

Chem. Dept. : Courses - Human Biochemistry (Bio 217 and Chem 117/217) 1972

Chem. Dept. : Courses - Human Biochemistry 1972

Chem. Dept. : Courses - Human Biochemistry 1973

Chem. Dept. : Courses - Human Biochemistry 1973

Chem. Dept. : Courses - Human Biochemistry IB 1974

Chem. Dept. : Courses - Human Biochemistry IB 1974

Chem. Dept. : Courses - Human Biochemistry IB 1974

Chem. Dept. : Courses - Human Biochemistry 1978 - 1979

Chem. Dept. : Courses - Human Biochemistry 117/217 1979

Chem. Dept. : Courses - Human Biochemistry 217 1979

Chem. Dept. : Courses - Human Biochemistry, n.d.

Chem. Dept. : Courses - Human Biochemistry, n.d.

Chem. Dept. : Courses - Human Biochemistry "Special", n.d.

Chem. Dept. : Courses - Introductory Biochemistry 1969

Chem. Dept. : Courses - Introductory Biochemistry (Bio 211/Chem 211) 1971

Chem. Dept. : Courses - Introductory Biochemistry (Bio 211/Chem 211) 1972

Chem. Dept. : Courses - Introductory Biochemistry (Bio 211/Chem 211) 1973

Chem. Dept. : Courses - Marine Biochemistry, McElroy/Kaplan (Bio 185) 1982

Chem. Dept. : Courses - Marine Biochemistry, McElroy/Kaplan (Bio 185) 1983

Chem. Dept. : Courses - Marine Biochemistry, McElroy/Kaplan (Bio 185) 1985

Chem. Dept. : Courses - Marine Biochemistry, McElroy/Kaplan (Bio 185) 1986

Chem. Dept. : Courses - miscellaneous class rosters 1970 - 1973

Chem. Dept. : Courses - Nutritional Biochemistry 1977

Chem. Dept. : Courses - Nutritional Biochemistry 1980

Chem. Dept. : Courses - Nutritional Biochemistry 1980

Chem. Dept. : Courses - Nutritional Biochemistry 1982

Chem. Dept. : Courses - Nutritional Biochemistry 1982

Chem. Dept. : Courses - Nutritional Biochemistry 1982

Chem. Dept. : Courses - Nutritional Biochemistry 1983

Chem. Dept. : Courses - Nutritional Biochemistry 1983

Chem. Dept. : Courses - Nutritional Biochemistry 1983 - 1984

Chem. Dept. : Courses - Nutritional Biochemistry 1984

Chem. Dept. : Courses - Nutritional Biochemistry 1984

Chem. Dept. : Courses - special studies 1986

Chem. Dept. - Departmental Council 1978 - 1979

Chem. Dept. - development of Biochemistry Program (1973; 1976)

Chem. Dept. - equipment allocations and space assignments 1968 - 1973

Chem. Dept. - equipment allocations and space assignments 1976

Chem. Dept. - equipment requested from departmental budget, state funds 1977

Chem. Dept. - Faculty Council, memos and reports (July - December 1979)

Chem. Dept. - Faculty Council, memos and reports (January - March 1980)

Chem. Dept. - Faculty Council, memos and reports (April - June 1980)

Chem. Dept. - Faculty Council, memos and reports (July - December 1980)

Chem. Dept. - Faculty Council, memos and reports 1981

Chem. Dept. - Medical School problem; debate over relations with campus depts. 1976 - 1979

Chem. Dept. - merit and performance reviews 1976

Chem. Dept. - newspaper clippings 1971 - 1982

Chem. Dept. - proposal to establish a biochemistry department 1983

Chem. Dept. - sabbatical request and leave report 1976

Chem. Dept. - teaching assignments 1968 - 1972

Chem. Dept. - Urey, Harold endowed chair 1981

Educational Policy Committee 1969 - 1970

Fourth college chemistry planning committee 1973

Interphase Committee on Biochemistry 1969 - 1970

Kaplan's Lab - alcohol, authorization to purchase from campus storeroom 1976 - 1984

Kaplan's Lab - Environmental Health and Safety memos, records and reports 1977 - 1984

Kaplan's Lab - Environmental Health and Safety service charges 1978 - 1984

Kaplan's Lab - human disease, application for permit to transport agents of 1981 - 1982

Kaplan's Lab - laboratory instruments ordered or to be ordered 1979

Kaplan's Lab - laboratory instruments received 1979

Kaplan's Lab - miscellaneous equipment orders and list (1977-78; 1981)

Kaplan's Lab - narcotics inventory 1977 - 1983

Kaplan's Lab - purchase orders, May - June 1979

Kaplan's Lab - radioisotope use authorization renewal 1977 - 1985

Kaplan's Lab - research projects, miscellaneous progress reports 1979

Kaplan's Lab - seminar with T.P. Wang, visiting scientist 1981 - 1982

Kaplan's Lab - Surge Facility, 303 Matthews Building 1970 - 1977

Kaplan's Lab - UCSD Foundation grant accounts, Brunswick Foundation, Inc. 1984 - 1986

Kaplan's Lab - UCSD Foundation grant accounts, Corning Glass 1978 - 1984

Kaplan's Lab - UCSD Foundation grant accounts, Corning Glass 1976 - 1986

Kaplan's Lab - UCSD Foundation grant accounts, Hoffman-LaRoche 1981 - 1982

Kaplan's Lab - UCSD Foundation grant accounts, Hoffman-LaRoche 1977 - 1984

Kaplan's Lab - UCSD Foundation grant accounts, Hoffman-LaRoche 1977 - 1986

Kaplan's Lab - UCSD Foundation grant accounts, Hoffman-LaRoche 1977 - 1986

Kaplan's Lab - UCSD Foundation grant accounts, Hyland 1984 - 1985

Malignant tumors among graduate students in physics - committee 1969 - 1970

Medical Scientists Training Program Committee 1968 - 1969

Proposal for biochemistry division at UCSD, n.d.

Proposal for cancer center in La Jolla 1969 - 1975

Proposal for enzyme preparation center at UCSD 1971

Proposal for macromolecular center 1970

Proposal for solar energy research institute 1974 - 1977

Research Showcase Committee, Chancellor's cmt. for high technology companies

School of Medicine - academic areas of concentration, n.d.

School of Medicine - Basic Science Teaching Ad Hoc Committee 1972

School of Medicine - Cancer Research Planning Committee (Oct. - Dec. 1971)

School of Medicine - Cardiovascular-Pulmonary Centers site visit

School of Medicine - Experimental Pathology Group (1972; 1976)

School of Medicine - faculty committees, members 1968 - 1972

School of Medicine - faculty meeting, bylaws of UCSD faculty, March 19, 1969

School of Medicine - Genetics and Metabolism Concentration Area Committee

School of Medicine - myocardial infraction study reports, 1973; 1975

School of Medicine - National Board of Medical Examiners, exam results

School of Medicine - Nomimating Committee 1970 - 1971

School of Medicine - Oncology Advisory Committee 1972 - 1975

School of Medicine - Physiology/Pharmacology Graduate Studies Committee 1970 - 1977

School of Medicine - Physiology/Pharmacology Graduate Studies Committee meeting

School of Medicine - Preclinical Advisory Ad Hoc Committee 1974 - 1975

School of Medicine - Recruitment and Admissions Committee 1968 - 1969

School of Medicine - Recruitment and Admissions Committee, members 1968 - 1970

School of Medicine - Specialized Center of Research, site visit rehearsal 1974 - 1976

School of Medicine - Student Affairs, student and advisor handbooks and misc.

Scripps Institution of Oceanography - Alpha-Helix Program, 1970; 1973

Scripps Institution of Oceanography - Alpha-Helix Program proposal 1974

Third college chemistry program planning committee 1969 - 1973

University of California, San Diego Foundation 1974

Phosphorolysis and synthesis of sucrose with a bacterial preparation 1943

Summary of the dissertation of Nathan Kaplan 1943

Observations with p32 of the changes in the acid-soluble phosphates in the... 1943

Radioactive phosphate as an indicator of the relationship between the... 1944

Effect of starvation and ageing on acid-soluble phosphate components of the live 1944

Aerobic phosphorylations in tissue slices 1945

Metabolism in diabetic coma produced by alloxan 1945

Report on a coenzyme for acetylation 1946

Common factor in the enzymatic acetylation of sulfanilamide and of choline 1946

Mechanism of enzymatic acetylation 1947

Chemistry and distribution of the coenzyme for acetylation (coenzyme a) 1947

Coenzyme for acetylation, a pantothenic acid derivative 1947

Metabolic studies in diabetic acidosis I. Effect of early admin. of dextrose 1947

Metabolic studies in diabetic acidosis II. Effect of admin. of sodium phosphate 1948

Reactions between acetate, acetyl phosphate and adenylic acid system in... 1948

Assay and distribution of coenzyme a 1948

Effect of pantothenic acid deficiency upon the coenzyme a content and ... 1948

Acetyl precursor in pyruvate synthesis in escherichia coli 1948

Intermediary metabolism of phosphorus compounds 1949

Liberation of pantothenic acid from coenzyme a 1949

Changes in enzymatic constitution in zinc-deficient neurospora 1951

Reaction of pyridine nucleotide with cyanide and its analytic use 1951

Effect of alkali on diphosphopyridine nucleotide 1951

Neurospora diphosphopyridine nucleotidase 1951

Pyridine nucleotides and coupled phosphorylation 1951

Carbohydrate metabolism 1951

Enzymatic deamination of adenosine derivatives 1952

Comparison of diphosphopyridine nucleotide with its deaminated derivative in... 1952

Pyridine nucleotide transhydrogenase I. Indirect evidence for the reaction... 1952

Pyridine nucleotide transhydrogenase II. Direct evidence for and mechanisms... 1952

Action of nicotinamide and isonicotinic acid hydrazide on diphosphopyridine... 1952

Nature of monoester phosphate group in coenzyme a 1952

Inhibition of spleen diphosphopyr. nucleotidase nicotinamide, an exchange react. 1953

Further studies of nutrition. condit. affect. enzymatic constit. in neurospora 1953

Specific b(eta) nucleotidase 1953

Competitive inhibition of hydroxlamine on alcohol dehydrogenase 1953

Cytochrome peroxidase from pseudomonas fluorescens 1953

Pyridine nucleotide transhydrogenase III. Animal tissue transhydrogenases 1953

Pyridine nucleotide transhydrogenase IV. Effect of adenylic acid a(lpha)... 1953

Pyridine nucleotide transhydrogenase V. Exchange react. studied with c14 1953

Biochemical career of Fritz Lipmann 1953

DPN specific glycerol dehydrogenase from aerobacter aerogenes 1953

Formation of the isonicotinic acid hydrazide analog of dpn 1953

Monoester phosphate grouping of coenzyme a 1954

Enzymatic degradation and resynthesis of coenzyme a 1954

Effect of isonicotinic acid hydrazide on diphosphopyridine nucleotidases 1954

Isolation and properties of the isonicotinic acid hydrazide analogue of dpn 1954

Significance of enzymatically catalyzed exchange reactions in chemotherapy 1954

Chemical reaction of hydroxylamine with diphosphopyridine nucleotide 1954

Action of hydroxylamine and cyanide on alcohol dehydrogenase of horse liver 1954

Direct evidence for a dpn - hydroxylamine complex with horse liver alcohol... 1954

Enzymatic preparation of triphosphopyridine nucleotide from dpn 1954

Function of inorganic iron in the reduction of cytochrome c 1954

3-acetylpyridine analog of dpn 1954

Pyridine nucleotide transhydrogenase VI. Mechanism and stereospecificity of... 1955

Preparation and properties of 3'-triphosphopyridine nucleotide 1955

Reaction of pyridine nucleotides with trifluoroacetic acid anhydride 1955

Symposium on electron transport in the metabolism of microorganisms 1955

Mechanisms involved in pyridine nucleotide action 1955

Effect of adenine nucleotides on reactions involving triphosphopyrid. nucleotide 1955

Isolation of a dpn isomer containing nicotinamide riboside in the alpha linkage 1955

Hexose phosphate and hexose reductase 1955

Significance of "heat-activated" enzymes 1956

D-mannitol 1-phosphate dehydrogenase from escherichia coli 1956

Pyridine nucleotide synthesis in the mouse 1956

Reduction of inorganic iron and cytochrome c by flavin enzymes 1956

Pyridine nucleotide analogs and the sulfhydryl nature of some fad enzymes 1956

Hexitol metabolism in escherichia coli 1956

Effects of oxygen, iron, and molybdenum on routes of electron transfer in... 1956

Cytochrome peroxidase from pseudomonas fluorescens 1956

Chemistry and properties of the 3-acetylpyridine analogue of dpn 1956

Phosphorylative and nonphosphorylative pathways of electron tranfer in rat... 1956

Reaction of pyridine nucleotide analogues with dehydrogenases 1956

Specific spectrophotometric assay for flavin adenine dinucleotide 1956

Large scale synthesis and purification of flavin adenine dinucleotide 1956

Possible enzymatic role of ergothioneine 1956

Distribution of enzymes cleaving pyridine nucleotides in animal tissues 1957

Flavoprotein-catalyzed pyridine nucleotide transfer reactions 1957

Reduced pyridine nucleotide pyrophosphatase 1957

Pyridine precursors of mouse liver diphospyridine nucleotide 1957

Pyridine coenzymes of subcellular tissue fractions 1957

Studies on the interaction of dpn analogs with dehydrogenases 1957

Preparation of pyridine nucleotide analogs by the carbonyl addition reaction 1957

Enzymatic properties of chemically prepared dpn analogs 1957

Mechanisms of flavoprotein-catalyzed pyridine nucleotide transfer reactions 1957

Addition of sulfhydryl compounds to dpn and its analogues 1957

Reaction of thiol compounds with pyridine nucleotides 1957

Yeast alcohol deydrogenase II. Properties of the catalytically active site 1957

Reactivity of the bound dpn of muscle triose phosphate dehydrogenase 1957

Yeast alcohol dehydrogenase III. Relation of alcohol structure to activity 1957

Relationship of structure to properties of dpn and other pyridinium compounds 1957

Mechanism of 'heat activation' of enzymes 1957

Effect of reserpine and promazine on dpn synthesis in liver 1958

Fluorescence studies of coenzyme binding to dehydrogenases 1958

Yeast alcohol dehydrogenase IV. Coenzyme binding sites 1958

Nicotinic acid analogue of diphosphopyridine nucleotide 1958

Nicotinamide riboside phosphorylase from human erythrosites... 1958

Nicotinamide riboside phosphorylase from human erythrosites... 1958

Mechanism for pyridine-nucleotide-dependent dehydrogenases 1958

Heat-activated dpn pyrophosphatase from proteus vulgaris 1958

Significance of induced in vivo sythesis of diphosphopyridine nucleotide 1958

Enzyme-coenzyme-substrate complex. of pyridine nucleotide depend. dehydrogenases 1958

Diaphorases of rat-liver mitochondria 1958

Flavin adenine dinucleotide synthesis in animal tissues 1958

Effect of pyridine derivatives on animal tissue diphosphopyridine nucleotideases 1959

Uptake of p32 in resting cells of clostridium perfringens 1959

Structure of dihydrodiphosphopyridine nucleotide 1959

Chemical properties of 3-substitited pyridine analogues of dpn 1959

Enzymatic studies with analogues of diphosphopyridine nucleotide 1959

Relationship of 3a(alpha)-hydroxysteroid dehydrogenase to pyridine... 1959

Effect of azaserine (o-diazoacetyl l-serine) on the pyridine nucleotide... 1959

Formation of nicotinic acid analogue of dpn after nicotinamide administration 1959

Effects of substrates on the swelling and loss of pyridine nucleotides from... 1959

Molecular heterogeneity and evolution of enzymes 1960

D- and l- lactic acid dehydrogenases in lactobacillus plantarum 1960

Antileukemic action of two thiadiazole derivatives 1960

Interaction of nicotinamide with reserpine and chlorpromazine III. Some... 1960

Coenzyme metabolism on the brain 1960

Comparison of some vic glycol dehydrogenase syst. found in aerobacter aerogenes 1960

Adaptive formation of a vic glycol dehydrogenase in aerobacter aerogenes 1960

Mechanism of depletion of mitochondrial pyridine nucleotides 1960

Metabolic pathways involving niacin and its derivatives 1960

Phosphopyridine nucleotidases and their protein inhibitors in the genus bacillus 1960

Spectrophotometric study of thionicotinamide analogue of dpn 1960

Measurements of enzymes in the diagnosis of acute myocardial infarction 1961

Conversion of pyridine hydroxamic acids to amides by mouse liver mitochondria 1961

Effect of azaserine on the biosynthesis of diphosphopyridine nucleotide in mouse 1961

Metabolites of nicotinamide in mouse urine: effects of azaserine 1961

Incorporat. of isotopically labeled precursors into pyrid. nucleotide coenzymes 1961

Pyridine nucleotide transhydrogenase VIII. Properties of the... 1961

Preparation and properties of n-hydroxyethyl derivatives of adenosine,... 1961

Evolution and differentiation of dehydrogenases 1961

Interactions in pyridine nucleotides 1961

Heterogeneity of the lactic dehydrogenases of new-born and adult rat heart as... 1961

Regulatory effects of enzyme action 1961

Effect of proteolysis and urea treatment on coenzyme binding to beef-heart... 1961

Inhibition of dehydrogenase reactions by a substance formed from reduced dpn 1961

D-mannitol l-phosphate dehydrogenase and d-sorbitol 6-phosphate dehydrogenase... 1962

Symposium on multiple forms of enzymes and control mechanisms I. Multiple... 1962

Preparation and properties of some nicotinamide adenine dinucleotide analogues.. 1962

Nature and development of lactic dehydrogenases 1962

Fluorescence of pyridine nucleotides in mitochondria 1962

Lactic dehydrogenases and muscular dystrophy in the chicken 1962

Nicotinamide adenine dinucleotidase 1962

Solubilization and purification of diphosphopyridine nucleotidase from pig brain 1962

Toxicity and antileukemic effectiveness of pyridine derivatives and... 1962

Hydroxyethylation and subsequent hydrolysis of deoxyguanosine at ph 7 and 25 1962

Pig-spleen pyridine transglycosidase I. Purification and properties 1962

Functions of the two forms of lactic dehydrogenase in the breast muscle of birds 1963

Immunological characteristics of dehydrogenases 1963

Physiochemical proper. of pig and horse heart mitochondrial malate dehydrogenase 1963

Structural factors in succinate-induced reduction of mitochondrial pyridine... 1963

Substituted nicotinamide analogues of nicotinamide adenine dinucleotide 1963

Analogs of pyridine coenzymes 1963

Starch-gel electrophoresis of malate dehydrogenase 1963

Structural and catalytic alterations of dehydrogenases after photooxidation 1963

Developmental changes of mammalian lactic dehydrogenases 1963

Evidence for two forms of m-type lactate dehydrogenase in the mouse 1963

Role of the sulfhydryl groups of lactic dehydrogenases 1963

Lactic acid racemization in clostridium butylicum 1963

Sulfhydryl content of some lactate dehydrogenases 1963

Alterations of tissue lactate dehydrogenase in human neoplasms 1963

Reaction of diphosphopyridine nucleotide and related pyridinium salts with alkal 1963

Lactic dehydrogenases: functions of the two types 1964

Hexitol dehydrogenases of bacillus subtilis 1964

Comparative enzymology of triosephosphate dehydrogenase 1964

Oxidative phosphorylation and terminal electron transport 1964

Evolution of lactic dehydrogenases 1964

Effect of tetrathionate on stability and immunological properties of muscle... 1964

Hybridization of lactic dehydrogenases in vitro by concentrated sodium... 1964

Lactate dehydrogenase - structure and function 1964

Lactic dehydrogenase in cancer 1964

Comparative enzymology of lactic dehydrogenases II. Properties of the... 1964

Studies of protein and bound coenzyme fluorescence of lactate dehydrogenases 1964

New concepts of the use of inhibitors in chemotherapy 1964

Role of the two types of lactic dehydrogenases 1964

Effects of freezing on enzymes 1965

Lactic acid racemization 1965

Structural and functional properties of h and m subunits of lactic dehydrogenase 1965

Factors influencing the concentration of enzymes in various muscles 1965

Effect of hormones and environmental factors on lactic dehydrogenases 1965

Isoenzymes in clinical diagnosis 1965

Fluorescence and coenzyme binding characteristics of serum albumin 1965

Interacting binding sites of l-specific lactic dehydrogenase of escherichia coli 1965

Influence of antibody on interact. between nucleotides and glutamic dehydrogenas 1965

Studies on the mechanism of hybridization of lactic dehydrogenases in vitro 1965

Reversible inactivation of dehydrogenases 1966

Enzymatically active conformers of mitochondrial malate dehydrogenase 1966

Immunology and rates of enzyme evolution in the amphibia in relation to the... 1966

Geographic variation in lactate dehydrogenases of rana pipiens and rana palustri 1966

Purification and properties of chicken heart mitochondrial and supernatant... 1966

Regulation of enzyme and coenzyme levels 1966

Pyridine nucleotide transhydrogenase in normal human and leukemic leukocytes 1966

Purification and characterization of diphosphopyridine nucleosidase from pig bra 1967

Solubilization and comparitive properties of some mammalian dpn(ases) 1967

Purification and kinetic characteristics of dogfish liver glutamate dehydrogenas 1967

Malate dehydrogenases II. Purification and properties of bacillus subtilis,... 1967

Evolution of creatine kinase 1967

Malate dehydrogenases III. Alteration of catalytic properties during... 1967

Comparative enzymology of lactic dehydrogenases 1967

Kinetic studies of dogfish liver glutamate dehydrogenase with... 1967

Enzymatic identification of fish products 1967

Concepts and significance of enzyme evolution 1967

Studies on malate dehydrogenases and aspartate aminotransferases from... 1967

On the tissue specificity and biological sigificance of aldolase c in the chicke 1967

Salt-induced alteration of d(-) lactate dehydrog. from polysphondylium pallidum 1967

Purification of arginine kinase from lobster and a study of some factors... 1967

Malate dehydrogenases I. Survey of molecular size measured by gel filtration 1967

Untitled; article on clinical applications of advances in enzymology 1967

Developmental multiplicity of chicken aldolase 1967

Iodination of muscle fructose diphophate aldolase 1968

Regulation of pyridine nucleotide coenzymes 1968

Chemical characterization of d-lactate dehydrogenase from escherichia coli b 1968

Kinetics of escherichia coli b d-lactate dehydrogenase and evidence for... 1968

3-acetylpyridine: effects in vitro related to teratogenic activity in... 1968

Significance of substrate inhibition of dehydrogenases 1968

D-lactate specific pyridine nucleotide lactate dehydrogenase in animals 1968

Characteristics of microbial dpn(ases) containing exceptionally large amounts... 1968

Investigation of the confirmation of b(eta)-dpn (beta-nicotinamide-adenine... 1968

Chicken heart soluble aspartate aminotransferase purification and properties 1968

Characteristics of arthropod arginine kinases 1968

Investigation of inter- and intramolecular interactions in flavin-adenine... 1968

Antibody studies with multiple enzymes of horse liver alcohol dehydrogenase II 1968

Denaturation of glutathione reductase and lipoyl dehydrogenase 1968

Nature of multiple molecular forms of enzymes 1968

220mhz nuclear magn. reson. spectra of oxidized and reduced pyridine dinucleotid 1969

Lactate dehydrogenase of lobster (homarus americanus) tail muscle 1969

Purification and properties of a dpnh-tpnh diaphorase from clostridium kluyverii 1969

Agar gel electrophoretic demonst. of charge alterat. in mutant bacterial protein 1969

Subunits of dogfish m4 lactic dehydrogenase 1969

Purification and properties of two types of dpn-linked glycerol 3-phosphate... 1969

220mhz proton nuclear magnetic resonance study of the geometric disposition... 1969

Purification and substrate specificities of bacterial hydroxysteroid dehydrogena 1969

Potential of measurement of enzyme changes in the evolution of acute... 1969

Accumulation of oxidized dpn in mouse liver after administration of reduced dpn 1970

Formation of a ternary complex between diphtheria toxin,... 1970

Physiological concentrations of lactate dehydrogenases and substrate inhibition 1970

Purification and properties of the pyridine nucleotide transhydrogenase from... 1970

Kinetic charact. of pyrid. nucleotide transhydrogen. from pseudomonas aeruginosa 1970

Stereospecificity of hydrogen transfer reactions of pseudomonas aeruginosa... 1970

220 mhz proton nuclear magnetic resonance study of the interaction between... 1970

Mitochondrial malate dehydrogenase: further stud. on mult. electrophoretic forms 1970

Investigation of the configuration and conformation of... 1970

High frequency nuclear magnetic resonance investigation of the backbone of... 1970

Activation effect of 2'-adenylic acid on bacterial transhydrogenases 1970

Structure of pyridine coenzymes as related to binding 1970

Studies on conform. of mult. forms of chicken heart aspartate aminotransferase 1970

Evolution of pyridine nucleotide linked dehydrogenases 1970

Autobiography and essays: wanderings of a biochemist 1971

Physical & chemical properties of reversibly inactivated lactate dehydrogenases 1971

Addition prod. of diphosphopyridine nucleotides with substrates of pyridine... 1971

Structure of pyridine nucleotides in solution 1971

Role of the reduced diphosphopyridine nucleotide in the reactivation of... 1971

Formation of ternary complexes by dpn-dependent dehydrogenases 1971

Comments on the conformation of pyridine coenzymes in aqeous solutions 1971

Lactate dehydrogenase specific to the liver of gadoid fish 1972

Pyridine nucleotides in norm. and nicotinamide depleted adrenal tumor cell cultu 1972

Biologically active catecholamines covalently bound to glass beads 1972

Identification of lactate dehydrogenase isoenzymes by rapid kinetics 1972

Association by hydrogen bonding of mononucleotides in aqueous solution 1972

Complexes of pyridine nucleotides and their function 1972

Regulatory characteristics of lactate dehydrogenases 1972

Pyridine nucleotide transhydrogenases 1972

Separate physiological roles for two isozymes of pyridine nucleotide-linked... 1972

Allosteric effect of 2'-adenylic acid on the pseudomonas pyridine nucleotide... 1972

Lactate dehydrogenases: structure and function 1972

DPN-linked d-lactate dehydrogenases from the horseshoe crab, limulus... 1973

Immobilized catecholamine and cocaine effects on contractility of cardiac muscle 1973

Conformations of diphosphopyridine coenzymes upon binding to dehydrogenases 1973

Immobilized enzymes: catalytic properties of lactate dehydrogenase covalently... 1973

Aminoacid sequence of dogfish m4 lactate dehydrogenase 1973

Structure-function relationship in lactate dehydrogenase 1973

Apparatus for determin. of kinetic parameters assoc. with immobilized enzymes 1973

Hydrogen evolution by a chloroplast-ferredoxin-hydrogenase system 1973

Conformational changes induced in dihydrofolate reductase by folates,... 1973

Studies on the mitochondrial energy-linked pyridine nucleotide transhydrogenase 1973

Lactate dehydrogenases: structure and function 1973

Stability of catecholamines immobilized on glass beads 1974

Purification and separation of pyridine nucleotide-linked dehydrogenases by... 1974

Intramolecular hydrogen bonding in flavin adenine dinucleotide 1974

Determination of the absolute stereospecificity of the enzymatic reduction of... 1974

NADase: types and functions 1974

8-(6-aminohexyl)-amino-adenine nucleotide derivat. for affinity chromatograpy 1974

Proton relaxation studies of diphosphopyridine coenzymes 1974

Structure of the primary acid rearrangement product of reduced nicotinamide... 1974

Glyceraldehyde-3-phosphate dehydrogenase catalyzed hydration of 5-6 double ... 1974

Immobilized lactate dehydrogenases 1974

Determination of the activity and concentration of immobilized and soluble... 1974

Lack of detectable change in cyclic amp during the cardiac inotropic response... 1975

On the properties of matrix bound lactate dehydrogenase 1975

Kinases and creatine kinases by affinity chromatography 1975

Amino acid seq. of tryptic peptides isolated from dogfish m4 lactate dehydrogen. 1975

Structure and quantitation of catecholamines covalently bound to glass beads 1975

Possible role for glass bead immobilized enzymes as therapeutic agents... 1975

Revertants of escherichia coli mutants defective in the cyclic amp system 1975

Determination of solution structure of diphosphopyridine coenzymes with... 1975

Mechanisms of action and biological functions of various dehydrogenase isozymes 1975

Purification & properties of malate dehydrogenase from pseudomonas testosteroni 1975

New instrum. for rapid determin. of activities of lactate dehydrogen. isoenzymes 1975

Alpha beta epimerization of reduced nicotinamide adenine dinucleotide 1975

Characteristics of 8-substituted adenine nucleotide derivatives utilized in... 1975

Pyridine nucleosidases from bacillus subtilis and neurospora crassa:... 1975

Pyridine nucleosidase from bacillus subtilis: kinetic properties and... 1975

Some characteristics of nad glychohydrolase from neurospora crassa conidia 1975

Biological activity of catecholamines covalently linked to synthetic... 1976

Affinity isolation of cultured tumor cells by means of drugs and hormones... 1976

8-alkylaminoadenyl nucleotides as probes of dehydrogenase interactions with... 1976

Diphtheria toxin effects on human cells in tissue culture 1976

Interaction of c13-enriched folate with dihydrofolate reductase studied by... 1976

Target directed cancer chemotherapeutical agents 1976

Immobilization of hydrogenase on glass beads 1976

General ligand affinity chromatography in enzyme purification 1976

Proton magnetic resonance study of the intramolecular association and... 1976

Regulatory properties of the pyridine nucleotide transhydrogenase from... 1976

Regulatory properties of the pyridine nucleotide transhydrogenase from... 1976

Pyridine nucleotide transhydrogenase from pseudomonas aeruginosa:... 1976

Determination of hydride transfer stereospecificity of nicotinamide adenine... 1976

Proton magnetic resonance studies on the binding of conenzymes to dehydrogenases 1976

Insomerization of the binary complex of reduced acetylpyridine adenine... 1977

Investigations into relation. between structure & function of diphtheria toxin 1977

Chromatium hydrogenase 1977

P31 nuclear magnetic resonance studies of hela cells 1977

Purification of kinases by general ligand affinity chromatography 1977

Pseudomonas aeruginosa transhydrogenase: affinity of substrates for the... 1977

Stereospecificity of bacterial external flavoprotein monooxygenases for... 1977

Physical and chemical properties of lactate dehydrogenases in homarus americanus 1977

Some of the variables affecting the success of transplantation of human... 1977

Active subunits of yeast aldehyde dehydrogenase and chicken muscle... 1977

Nomenclature of pyridine coenzymes 1977

Streptozotocin - possible mediation of a cytotoxic action via interaction... 1977

Disulfide bond connecting the chains of ricin 1978

Rationale for stabiliz. of oxyg.-labile enzy.: appl. to a clostridial hydrogen. 1978

Enzyme stereospecificities for nicotinamide nucleotides 1978

Mechanism of lactic acid oxidation catalyzed by lactate dehydrogenase from the.. 1978

Approaches to chemotherapy using the athymic nude mouse 1978

Proton mag. reson. study of 8-(6-aminohexyl)-aminoadenosine 5'-monophosphate 1978

Stereospecificity of intramolecular association of reduced pyridine coenzymes 1978

Guanosine nucleotide analogues as general ligands in affinity chromatography 1978

Biological activity of isoproterenol covalently linked to synthetic polypeptides 1978

Regulation of lactate dehydrogenase synthesis in bacillus subtilis 1978

Synthesis of 8-(6-aminohexyl)-amino-gmp and its applications as a general... 1978

Reproducibility of glass bead immobilized drug preparations 1978

Chemical modification of lysines of the toxic lectin ricin 1978

Chemical modification of tyrosines of the toxic lectin ricin 1978

Irreversible binding of ricin to hela cells 1978

Chemical modif. of nadase & its natural protein inhibitor from bacillus subtilis 1978

Initial studies on the biological activity of diphtheria toxin 1978

Isolation and initial characterization of 1,2-propanediol-utilizing enzyme... 1978

Studies of bovine liver glutamate dehydrogenase by analytical affinity... 1979

Passive transfer of lymphocytes from diabetic man to athymic mouse 1979

Antineoplastic activity of poly (l-lysine) with some ascites tumor cells 1979

Probing sensitivity of p31 nmr chemical shifts to hydrogen bond. to stereochem. 1979

Purification of phosphotransacetylase by affinity chromatography 1979

Proton nuclear magnetic resonance study of the conformation and configuration... 1979

Chemical and biological aspects of peptide catecholamine conjugates 1979

Chelating agents protect hydrogenase against oxygen inactivation 1979

Interaction of c13 (benzoylcarbonyl)-folate and... 1979

Synthesis of 8-(6-aminohexyl)-amino-gtp and gdp and their application as... 1979

Immobilized enzymes in biochemical analysis 1979

h1 nmr study of the conform. & config. of cyclized pyridine nucleotide adducts 1979

Approaches to stabiliz. of hydrogenase & nitrogenase against oxygen inactivation 1979

Assignment of c13 nmr bands of labeled tryptophan in lactobacillus casei... 1979

Synthesis and biological activity of 6-amino substituted catecholamines 1979

Role of ethanol extractable proteins from the 80s rat liver ribosome 1980

Streptozotocin-induced diabetes in athymic and conventional balb/c mice 1980

Thermal stabilities of membrane-bound, solubilized, and artificially ... 1980

Highly efficient induct. of type c retroviruses by a human tumor in athymic mice 1980

Kamen Symposium draft 1980

Purification, properties, and kinetic mechanism of coenzyme a-linked aldehyde... 1980

Induction of lymphoma in athymic mice: a model for study of the human disease 1980

Lectins from chicken tissues are mitogenic for thy-1 negative murine spleen cell 1980

New doxorubicin analogs active against doxorubicin-resistant colon tumor... 1980

On the role of the covalent carbohydrate in the action of ricin 1980

Oxidative phosphorylation and atpase activities of human tumor mitochondria 1980

Reduced nicotinamide 8-(alkylamino) adenine dinucleotides: enzyme-coenzyme... 1980

Immobilized ricin a chain and its inactivation of ribosomes 1980

Polymer & protein bound anthracyclines, synth. & antineoplastic activ. in-vitro 1980

Serotonin modulation of norepinephrine-induced increases of adenosine... 1980

Structure and activity of a trypsin nicked ricin 1980

Therapeutic response of human tumor xenografts in athymic mice to doxorubicin 1981

Creatine kinase isozymes in human tumors 1981

Variable atpase composition of human tumor plasma membranes 1981

Interleukin 2 is mitogenic for nu/nu and nu/+ murine spleen cells 1981

Induction of t- & b-lymphocyte respons. in antigenically stimulated athymic mice 1981

Isolation and characterization of plasma membranes from transplantable human... 1981

Effect of 4' doxorubicin analogs on heterotransplantation of human tumors in... 1981

Effect of electron carriers and other ligands on oxygen stability of... 1981

Chemotherapy of human colorectal tumor xenografts in athymic mice with... 1981

Changing biochemical concepts in cancer research 1981

Anticellular activity of human interferons 1981

Biological functions of lactate dehydrogenase 1981

Activity of cancer chemotherapy agents against human colorectal carcinomas... 1981

Monovalent ricinus communis agglutinin: comparisons to ricin 1981

Trigon of host, tumor and anthracycline in single drug and combination therapy 1981

Comparative antineoplastic activity of n-trifluoroacetyl... 1981

Induction of lymphoma in antignically stimulated athymic mice 1982

Remarks on science and society 1982

Activity of the acidic phosphoproteins from the 80s rat liver ribosome 1982

Induction of sarcomas in athymic mice 1982

Differentiation and activation of nu/nu splenic t cell precursors by mature... 1982

In vitro responses of nude mouse-xenografted human colon carcinomas exposed... 1982

Action of ricin a-chain on ribosomes 1982

Acid phosphatase in the plasma membranes of human astrocytoma showing marked... 1982

Induction of a t-cell-like response in athymic mice 1982

Human tumor-induced expression of endogenous murine leukemia viruses of... 1982

Antiproliferative assay for human interferons 1982

Effective interferons in nude mice 1982

Effects of specific amino acid modification upon catalytic & regulatory propert. 1982

Lack of potentiation of combination chemotherapy with 5-fu and... 1982

Monoclonal antibody and an antibody-toxin conjugate to a cell surface... 1983

Amplification of the murine leukemia virus mr 70,000 glycoprotein gene... 1983

Antitumor activity and cardiotoxicity in mice of a new doxorubicin analog:... 1983

Poly (l-lysine) as an antineoplastic agent and tumor-specific drug carrier 1983

Correlation of drug sensitivity on human colon adenocarcinoma cells grown in... 1983

Characterization of catecholamine-polypeptide conjugates 1983

Historical perspectives on purification of biomolecules 1983

Leukemia virus-related protein in the murine pancreas 1984

Use of athymic mice in the screening of new anthracycline derivatives 1984

In vivo synergestic anti-tumor effect of a mouse monoclonal antibody to... 1984

Kinetics of protein synthesis inactivation in human t-lymphocytes by... 1984

Lactate dehydrogenase manuscript 1984

Model studies and biological activity of analogs 1984

Demonstration of separate phosphotyrosol- and phosphoseryl-histone... 1985

Studies on oncogenesis in the athymic mice 1985

History of the pyridine nucleotides 1985

Experiences in biochemistry 1985

Role of pyridine nucleotides in regulating cellular metabolism 1985

Assay of td activity with tpnh-tndpn and of dd activity with dpnh-apdpn

Binding of c4 deuterium-labeled reduced coenzyme analogs to dehydrogenases

Binding of pyridine nucleotides to diphtheria toxin

Characterization of a novel enzyme from neisseria gonorrhoeae

Chemistry and pharmacology of catecholamines and other low molecular weight...

Control of the synthesis of malate dehydrogenase in aerobacter aerogenes

Determination of isoenzymes of dehydrogenases and kinases by assays with...

Evolution of dehydrogenases

Evolutionary changes in electrophoretic mobility and temperature stability of...

In vitro activation of ricin and nicked diphtheria toxins by lysosomes

Isozymes

Miscellaneous drafts

Molecular basis for inherited disorders

NMR studies of binding diphosphopyridine coenzymes to diphtheria toxin and...

Parallel evolution of enzymes

Pyridine coenzymes

Pyridine nucleotides

Serial serum lactic dehydrogenase determin. as an index of cancer chemotherapy

Target directed cancer chemotherapeutical agents

Usefulness of the athymic nude mice in the cancer research: experimental...

Arnold, L. J. and K. S. You - Determination of the hydride transfer... 1978

Brodelius, Peter - Industrial applications of immobilized biocatalysts 1978

Buonassisi, V. - Hormone and neurotransmitter receptors in an established...

Driscoll, Gerry - malic dehydrogenase draft 1965

Eppenberger, H. - enzyme creatine kinase draft 1968

Everse, Johannes - miscellaneous drafts, 1960's and n.d.

Everse, Johannes and L. Bernstein - Studies on the binary & ternary complexes... 1974

Everse, Johannes - Warburg paper draft 1963

Fondy, T. - Diphosphopyridine nucleotide-c14 (carboxyl-c14-nicotinamide)...

Klibanov, A. M. - Immobilization as a method of enzyme stabilization against...

Klibanov, A. M. and N. M. Weare - Oxygen inactivation and stabilization of... 1979

Knowles, A. F., R. Isler and J. Reece - Common occurrence of atp... 1982

Lee, Chi-Yu - Preparation of 8-(6-aminohexyl)-amino-nad+; n.d.

Lee, Chi-Yu - Yeast aldehyde dehydrogenase 1978