Minutes, financial records, correspondence, memoranda, notes, lists, clippings, reprints, pamphlets, draft articles, periodicals. This collection focuses on the Society's efforts against the 1938 initiative, and offers a look into the organization and workings of a successful political campaign. There are also materials referencing earlier and later campaigns around the same issue.

This organization, founded in 1915 but minimally active since the 1922 defeat of a California antivivisection initiative, was reorganized in 1937 to work against the proposed State Humane Pound Law (initiative number 2 on the November 8, 1938 ballot). The Society apparently also opposed another such initiative in 1948. The Society's purpose was expressed in Article II of its By-Laws: "The purpose of the Society is to disseminate accurate information as to the methods and benefits of animal experimentation and to stimulate and guard scientific research." The 1937 reorganization created a Northern California committee with offices on Pine Street in San Francisco and a Southern California committee with offices in the Chamber of Commerce building in Los Angeles.

Collection is open for research.