Morris E. Friedkin Papers
Special Collections & Archives
Special Collections & Archives, UC San Diego
Copyright 2005
9500 Gilman Drive
La Jolla 92093-0175
spcoll@ucsd.edu
Descriptive Summary
Languages:
English
Contributing Institution:
Special Collections & Archives, UC San Diego
9500 Gilman Drive
La Jolla 92093-0175
Title: Morris E. Friedkin Papers
Identifier/Call Number: MSS 0524
Physical Description:
12.3 Linear feet
(26 archives boxes and 16 oversize folders)
Date (inclusive): 1919 - 1992
Abstract: Papers of Morris Friedkin, American biochemist, professor and university administrator. His research interests included folic
acid metabolism, cancer chemotherapy, enzymology, DNA synthesis, biochemical dynamics of the cell cycle, pharmacology, and
positron emission tomography. Materials include laboratory notebooks, loose notes, data, chemical and research product subject
files; reprints and typescripts of published and unpublished writings by Friedkin; documents related to grants and fellowships;
annotated writings by others; and correspondence. Also included are course materials and notes from Friedkin's time as student
at Iowa State College and at University of Chicago; and teaching materials and administrative materials from his time as a
faculty member and/or administrator at Washington University, Tufts University, and the University of California, San Diego.
OFF-SITE STORAGE
COLLECTION STORED OFF-SITE: ALLOW ONE WEEK FOR RETRIEVAL OF MATERIALS
Scope and Content of Collection
The Morris E. Friedkin Papers document the professional career of the American biochemist whose research interests throughout
his lifetime included folic acid metabolism, cancer chemotherapy, enzymology, DNA synthesis, the biochemical dynamics of the
cell cycle and cell growth, pharmacology, the use of radioactively-labeled molecules in biochemical research, and positron
emission tomography. Materials reflecting Friedkin's scientific activities include an extensive but incomplete set of laboratory
notebooks, documents related to specific research projects, information Friedkin collected on specific chemicals and laboratory
products, loose data, miscellaneous research notes, and descriptions of laboratory techniques. Other materials include documents
related to Friedkin's grants and fellowships, correspondence, reprints and typescripts of Friedkin's writings, and manuscripts
or typescripts of lectures about his research. Also included are notes and materials from courses Friedkin took as an undergraduate
at Iowa State College and as a graduate student at the University of Chicago. Finally, the papers contain materials related
to Friedkin's teaching and administrative duties at the Washington University School of Medicine, Tufts University School
of Medicine, and the University of California, San Diego, School of Medicine. The papers are arranged in ten series: 1) BIOGRAPHICAL
MATERIALS, 2) CORRESPONDENCE, 3) EDUCATION MATERIALS, 4) GRANTS AND FELLOWSHIPS, 5) RESEARCH MATERIALS, 6) WRITINGS BY FRIEDKIN,
7) TEACHING AND ADMINISTRATIVE MATERIALS, 8) WRITINGS BY OTHERS, 9) MISCELLANEOUS MATERIALS, and 10) ORIGINALS OF PRESERVATION
PHOTOCOPIES.
SERIES 1: BIOGRAPHICAL MATERIALS
The BIOGRAPHICAL MATERIALS series, arranged alphabetically, contains materials documenting significant events in Friedkin's
life such as his birth certificate, his doctoral diploma, materials regarding his sabbatical leaves, and two personal logs
with regular entries.
SERIES 2: CORRESPONDENCE
The CORRESPONDENCE series is arranged in three subseries: A) Chronological Files, B) A to Z Files, and C) Letters of Recommendation.
A) The Chronological Files subseries is arranged chronologically. The order and content of these files remain unchanged from
their original state except that letters of recommendation written for or by Friedkin were seperated and placed into their
own folder in the Letters of Recommendation subseries.
B) The A to Z Files subseries, arranged alphabetically by correspondent, contains letters written to or from Friedkin from
1948 to 1987. Included is correspondence with the renowned biochemist and Friedkin's graduate advisor, Albert Lehninger.
C) The Letters of Recommendation subseries contains letters of recommendation, arranged chronologically, written by Friedkin
for students, colleagues, and employees. Also included are letters of recommendation written for Friedkin.
SERIES 3: EDUCATION MATERIALS
The EDUCATION MATERIALS series is arranged in three subseries: A) Iowa State College, B) University of Chicago, and C) Stanford
University.
A) The Iowa State College subseries, arranged alphabetically, contains materials related to courses Friedkin attended at
his undergraduate institution, Iowa State College, from 1939 to 1941. Materials include course notes, laboratory notes, written
reports, and course handouts from courses in biochemistry, chemistry, colloid chemistry, and sanitary bacteriology.
B) The University of Chicago subseries, arranged alphabetically, contains materials related to courses Friedkin attended
at his graduate institution, the University of Chicago, from 1942 to 1948. Materials include course notes and notebooks, laboratory
notes and notebooks, course handout, written assignments, and copies of examinations from courses in biochemistry and genetics.
C) The Stanford University subseries, arranged alphabetically, contains materials from a course in microbiology Friedkin
took at Stanford University in 1956. Materials include course notes and notebooks, a poster of microrganisms, and course handouts.
SERIES 4: GRANTS AND FELLOWSHIPS
The GRANTS AND FELLOWSHIPS series is arranged in two subseries: A) New Antagonists of Amethopterin-Resistant Leukemia and
B) Miscellaneous.
A) The New Antagonists of Amethopterin-Resistant Leukemia subseries, arranged chronologically, contains documents related
to Friedkin's longest continuous grant from the Department of Health, Education and Public Welfare at the National Institutes
of Health for the funding of a project entitled "New Antagonists of Amethopterin-Resistant Leukemia" from 1968 to 1985. Included
are grant applications, correspondence, notices of research projects, progress reports, project evaluations, and documents
related to Friedkin's subcontracting of SRI International.
B) The Miscellaneous subseries, arranged chronologically, contains materials related to Friedkin's other grants and fellowships.
Materials include applications, correspondence, and miscellaneous records from Friedkin's United States Public Health Service
postdoctoral fellowship at the University of Copenhagen in 1948 to his application to the University of California, San Diego,
for funding of a project entitled "Synthesis of Difluoromethylornithine" in 1988.
SERIES 5: RESEARCH MATERIALS
The RESEARCH MATERIALS series is arranged in four subseries: A) Laboratory Notebooks and Notes, B) Projects, C) Chemical
and Product Information, and D) Data and Laboratory Techniques.
A) The Laboratory Notebooks and Notes subseries, arranged alphabetically, contains laboratory notebooks and loose research
notes from the 1940s to the 1980s. Included are loose notes from short periods during which Friedkin worked at the Brookhaven
National Laboratory in the 1950s, 1960s, and 1980s. Also included are laboratory notebooks which Friedkin numbered from the
period of his dissertation research at the University of Chicago in the late 1940s to the period of his research at the University
of California, San Diego, in the late 1970s. Although the labels on the notebooks are numerically discontinuous, the content
of the notebooks are continuous chronologically from 1946 to 1973. Also included are a few unnumbered laboratory notebooks
and a folder of miscellaneous research notes.
B) The Projects subseries, arranged alphabetically, contains materials related to specific research projects from 1968 to
1988. Materials include loose research notes, data, graphs, writings by others, and photographs or other illustrations for
projects on phosophoserine, cell proliferation, colchine, DNA, folic acid, microtubules, a possible leukemia inhibitor, and
thymidylate synthetase.
C) The Chemical and Product Information subseries, arranged alphabetically, contains materials collected by Friedkin concerning
chemicals or laboratory products of interest and possibly used in his research. Included are writings by others annotated
by Friedkin, notes, and product pamphlets.
D) The Data and Laboratory Techniques subseries, arranged alphabetically, contains materials which are not related to any
of the materials in the other RESEARCH MATERIALS subseries. Included are data collected by Friedkin's students and research
assistants, data from specific experiments, annotated writings by others on laboratory techniques, and typescripts of laboratory
protocols.
SERIES 6: WRITINGS BY FRIEDKIN
The WRITINGS BY FRIEDKIN series is arranged in three subseries: A) Numbered Publications, B) Lectures, and C) Unnumbered
Publications and Unpublished Writings.
A) The Numbered Publications subseries, arranged chronologically, contains reprints, typescript drafts, and drafts of figures
for writings published by Friedkin in professional and scholarly journals from 1945 to 1985. Included is a publication list
from the collection that lists Friedkin's publications chronologically and numbers them from 1 to 122. The set of numbered
publications is incomplete.
B) The Lectures subseries, arranged chronologically, contains materials from lectures Friedkin gave on various biochemical
topics at professional conferences or at other universities. Included are miscellaneous lecture announcements and manuscripts
or typescripts of his lectures.
C) The Unnumbered Publications and Unpublished Writings subseries, arranged alphabetically, contains reprints or photocopies
of published articles that are not on the numbered publication list, manuscripts or typescripts of papers reviewed but not
accepted for publication, a typescript copy of Friedkin's dissertation, and other miscellaneous writings.
SERIES 7: TEACHING AND ADMINISTRATIVE MATERIALS
The TEACHING AND ADMINISTRATIVE MATERIALS series is arranged in three subseries: A) Washington University School of Medicine,
B) Tufts University School of Medicine, and C) UCSD School of Medicine.
A) The Washington University School of Medicine subseries, arranged chronologically, contains mostly course handouts and
manuscripts or tyepscripts of lectures for biochemistry or statistics courses taught by Friedkin. Included are photographs
of some of the research facilities at Washington University. Both the teaching and administrative materials are arranged chronologically,
but they are not interfiled. The teaching materials, arranged chronologically, appear first and any administrative materials
follow, also arranged chronologically.
B) The Tufts University School of Medicine subseries, arranged chronologically, contains both teaching and administrative
materials. Included are Tufts University School of Medicine yearbooks, a bound collection of articles produced by the faculty
of the Department of Biochemistry during Friedkin's time as chair of the department, newspaper clippings, miscellaneous administrative
materials, and two folders of miscellaneous laboratory floorplans. Also included are course handouts and typescripts of lectures
for courses Freidkin taught at Tufts. Teaching materials, arranged chronologically, appear first in the subseries while any
administrative materials, arranged chronologically, follow the teaching materials. The two groups of materials are not interfiled
within the subseries.
C) The UCSD School of Medicine subseries is arranged in the same manner as the previous two subseries with the teaching materials,
arranged chronologically, followed by the administrative materials, also arranged chronologically. Included are course handouts
and lecture manuscripts for biochemistry courses Friedkin taught in the 1970s. Also included are materials related to Friedkin's
work as provost of Revelle College (1974-1976), and a restricted file of documents related to Friedkin's role as an investigator
of a complaint of scientific misconduct.
SERIES 8: WRITINGS BY OTHERS
The WRITINGS BY OTHERS series, arranged alphabetically, contains reprints or typescripts of articles on biochemistry or related
topics, many with notations, collected by Friedkin.
SERIES 9: MISCELLANEOUS MATERIALS
The MISCELLANEOUS MATERIALS series, arranged alphabetically, contains materials unrelated to any other series in the collection.
Included are materials documenting Friedkin's attendance at various professional conferences, miscellaneous slides presumably
related to Friedkin's lectures, letters Friedkin wrote to politicians concerning the war in Vietnam, newspaper clippings,
and documents related to Friedkin's review of the graduate pharmacology program at the University of California, San Francisco.
SERIES 10: ORIGINALS OF PRESERVATION PHOTOCOPIES
The ORIGINALS OF PRESERVATION PHOTOCOPIES series contains the originals of brittle or high acid content documents that have
been photocopied.
Biography
Morris E. Friedkin was born on December 30, 1918, in Kansas City, Missouri. Upon finishing high school in 1936, he entered
Kansas City Junior College and received an A.A. in chemistry in 1938. Friedkin continued his education at Iowa State College
receiving a B.S. in chemistry in 1940 and an M.S. in analytical chemistry in 1941. After completing his master's degree, he
enrolled in the doctorate program in biochemistry at the University of Chicago where he was one of the first graduate students
of the renowned biochemist, Albert Lehninger. In 1948, Morris Friedkin completed his Ph.D. with the submission of his dissertation
entitled "Studies on Aerobic Phosophorylation." After receiving his doctorate, he continued his studies for one year as a
postdoctoral fellow of the National Institutes of Health at the University of Copenhagen.
Friedkin returned to the United States in 1949 and accepted a faculty position in the Department of Pharmacology at the Washington
University School of Medicine. In 1957, he joined the faculty of the Department of Pharmacology at the Tufts University School
of Medicine where he also served as chair of the department in addition to his teaching and research responsibilities. In
1969, looking to devote more time to research and less to administrative duties, he moved to the Department of Biology at
the University of California, San Diego, School of Medicine. For the remainder of his professional career at UCSD except for
a short appointment as provost of Revelle College (1974-1976), Friedkin focused exclusively on research and teaching.
Throughout his career, Friedkin worked in many different areas of biochemical research usually with the aim of developing
chemotherapies for medicinal application. While attending the University of Chicago, he worked as chemist on the "Penicillin
Project" at the Northern Regional Research Laboratory. In 1966, the United States Army contracted with Friedkin to explore
new areas in the development of drugs for malaria-resistance. Also in the 1960s, he began his career-long study of cancer
chemotherapy with particular interest in the treatment of leukemia. In the course of over forty years of scientific research,
Friedkin's contributions advanced scientific understanding in many areas of biochemistry including folic acid metabolism,
the biochemical basis of the cell cycle and cell growth, the use of radioactively labeled molecules in biochemical research,
molecular pharmacology, DNA synthesis, the structure and function of microtubules, and positron emission tomography. He published
regularly in scholarly journals throughout his career and was honored with membership to the National Academy of Sciences
in 1978.
Morris Friedkin retired from his position in the Department of Biology at the University of California, San Diego School
of Medicine in 1989. He died on September 19, 2002.
Preferred Citation
Morris E. Friedkin Papers, MSS 524. Special Collections & Archives, UC San Diego.
Acquisition Information
Not Available
Access
In accordance with state and federal law, materials in Box 3, Folder 18 and Box 24, Folder 12 are restricted until 2067.
Subjects and Indexing Terms
Molecular biologists -- Archives
Cancer -- Chemotherapy -- Research
Box 1, Folder 2
Diploma - University of Chicago
1948
Box 1, Folder 3
Employment materials - United States Department of Agriculture and University of Chicago
1941 - 1946
Box 1, Folder 4
Kaiser-Permenente Excellence in Teaching Award
1981 - 1982
Box 1, Folder 5
Letters of Certification from the Iowa State College Registrar
1940 - 1946
Box 1, Folder 6
Newspaper clippings mentioning Friedkin
1965 - 1975
Box 1, Folder 7
Notebook containing autobiographical, travel, and lecture notes from the period when Friedkin was at the University of Copenhagen
1948 - 1949
Box 1, Folder 8
Notebook containing some research related notes but primarily autobiographical journal entries
1957 - 1989
Box 1, Folder 9
Photograph - Friedkin in front of Geisel Library
Box 1, Folder 10
Sabbatic leaves - Program statements, sabbatical leave reports and correspondence
1972 - 1988
Box 1, Folder 11
Transcript of birth record
1919
Box 2, Folder 9
A to L - Miscellaneous
1948 - 1987
Box 2, Folder 10
M to Z - Miscellaneous
1948 - 1985
Box 2, Folder 12
Bertino, Joseph R.
1963 - 1989
Box 2, Folder 13
Bishop, George - Includes article manuscripts and glass slides
1958 - 1961
Box 2, Folder 15
Brunsletter, Byron C.
1948
Box 2, Folder 16
Gates, Betsy Jane
1978 - 1979
Box 2, Folder 17
Grossowicz, Nathan
1980 - 1982
Box 2, Folder 18
Hoffman-LaRoche Inc.
1979 - 1981
General note
Correspondents: Alan F. Cook, Michael Drzyzga and W. E. Scott.
Box 2, Folder 19
Huennekens, Frank M.
1965 - 1967
Box 2, Folder 20
Kalckar, Herman M.
1948 - 1978
Box 2, Folder 21
Koppelman, Ray
1963 - 1964
General note
Correspondence with Abel Hoffman is stapled to some of the Koppelman letters.
Box 2, Folder 22
Kornberg, Arthur
1959 - 1977
Box 2, Folder 23
Lederle Laboratories
1961 - 1963
General note
Correspondents: Robert B. Angier and E. L. Robert Stokstad.
Box 2, Folder 24
Lehninger, Albert L.
1949 - 1985
Box 2, Folder 25
Lindsley, Dan
1978 - 1979
Box 2, Folder 26
Livingston, David
1969 - 1982
Box 3, Folder 1
Lowry, Oliver H.
1949 - 1989
Box 3, Folder 2
Maloney, William F.
1966 - 1968
Box 3, Folder 3
Mathews, Christopher K.
1963 - 1965
Box 3, Folder 4
McQuade, Henry
1958 - 1975
Box 3, Folder 5
National Institutes of Health
1952 - 1984
General note
Correspondents: E. P. Cronkite, Irvin Fuhr, Abraham Goldin, Dwijendra K. Misra, Moreshwar Nadkarni, Mary V. Niemic, Kenneth
Paull, Frederick Stohlmann, and C. Gordon Zubrod.
Box 3, Folder 8
Rizack, Martin A.
1959 - 1960
Box 3, Folder 9
Roche Products Limited
1983
General note
Correspondents: Frank R. Atherton, C. H. Hassall and N. R. Rogers.
Box 3, Folder 10
Rozengurt, Henry (Enrique)
1979 - 1982
Box 3, Folder 11
Schwarz Laboratories Inc.
1959
Box 3, Folder 12
Silber, Robert
1962 - 1963
Box 3, Folder 15
Stone, Frederick L.
1948 - 1949
Box 3, Folder 16
Strominger, Jack
1961 - 1962
Box 3, Folder 17
Unidentified correspondents
Letters of Recommendation
Box 3, Folder 18
1953 - 1987
Conditions Governing Access note
Restrictions Apply
Box 3, Folder 20
Biochemistry, untitled - Course notes
1941
Box 3, Folder 21
Chemistry 512 - Course notes and lab materials
1941
Box 3, Folder 22
Chemistry 519, Microquant - Course notes
1941
Box 3, Folder 23
Chemistry 531 - Course notes
ca. 1941
Box 3, Folder 24
Colloid Chemistry - Course handouts and notes
1939
Box 3, Folder 25
Sanitary Bacteriology - Course notes, typescript drafts of assignments and handouts
1940
Box 4, Folder 1
Biochemistry 201 - Course handouts and examinations
1945 - 1946
Box 4, Folder 2-3
Biochemistry 202 - Course handouts, lab materials, notebook, and examinations
1945 - 1948
Box 4, Folder 4-6
Biochemistry 305 - Course handouts, notebooks, notes and examinations
1942 - 1948
Box 4, Folder 7-8
Biochemistry 306 - Course notes, handouts, notebook, and examinations
1946
Box 4, Folder 9
Course notes, handouts and written assignments
1945
Box 4, Folder 10
The Unity of Genetics and Biochemistry in Phenylpyruvic Oligophrenia - Typescript
1945
Box 4, Folder 11
Unidentified course notes
1950
Introduction to Microbiology
Box 4, Folder 12
Course description and notes
1956
Box 4, Folder 13, Oversize FB-282-09
New Antagonists of Amethopterin-Resistant Leukemia
Box 5, Folder 3
Progress Reports
1963 - 1987
Box 5, Folder 4
Correspondence
1968 - 1987
Box 5, Folder 5
Grant Applications
1968 - 1984
Box 5, Folder 6
Grant Applications Appendices
1968 - 1984
Box 5, Folder 7
Notices of Grant Awarded
1969 - 1985
Box 6, Folder 1
Applications for Continuation Grant
1970 - 1985
Box 6, Folder 2
Notices of Research Project
1976 - 1982
Box 6, Folder 3
Project Evaluations
1977 - 1985
Box 6, Folder 4
SRI International - Project proposal and correspondence
1980 - 1984
Box 6, Folder 5
United States Public Health Service Fellowship - Application, correspondence and progress report
1948
Box 6, Folder 6
Graduate Training Grant - Applications, progress reports, correspondence, and Tufts University pharmacology graduate program
guide
1960 - 1968
Box 6, Folder 7
Design of New Antifolates for Use in Drug-Resistant Malaria - Application, progress reports, photographs, and related article
reprints
1961 - 1967
Biochemistry of the Transition from Quiescence to Replicative Growth in the Cell Cycle..
Box 6, Folder 8
Guggenheim Fellowship - Application, notes, pamphlets, and correspondence
1972 - 1978
Box 6, Folder 9
Eleanor-Roosevelt International Cancer Fellowship - Application, notes, correspondence, and progress reports
1977 - 1979
Box 6, Folder 10
Macy Faculty Scholar Award - Application, notes and correspondence
1978
Box 6, Folder 11
Role of Cytoplasmic Microtubules in the Regulation of the Activity of Peptide Growth Factors - Applications to the National
Science Foundation and American Cancer Society
1981 - 1983
Box 6, Folder 12
Effects of Amino Acid Phosphonate (APBA) on the Growth of Mouse Leukemic Cells - Application and correspondence
1984
Box 6, Folder 13
Effects of 2-Amino-4-Phosphono-Butyric Acid on the Growth of L1210 Murine Leukemia Cells from Exponential... - Applications,
applications for continuation grant and correspondence
1985
Box 6, Folder 14
Inhibitory Effects of Phosphono Amino Acids on the G0/G1 Period of Leukemia Cells - Application and correspondence
1985 - 1988
Box 6, Folder 15
Inhibition of Leukemia Cells by Phosphono Amino Acids - Applications and correspondence
1985 - 1988
Box 6, Folder 16
Isolation and Identification of CERDLIN (Cation Exchange Resin Derived Leukemia Inhibitor) - Applications
1986
Box 6, Folder 17
Synthesis of Difluoromethylornithine - Application and notes
1988
Laboratory Notebooks and Notes
Box 7, Folder 1
Research notes - Miscellaneous
1959 - 1988
Brookhaven National Laboratory
Box 7, Folder 4
1962. Sodium Borohydride Tritium Experiments - Notebook, graphs, data tables, and photocopies of writings by others
Box 7, Folder 5
1962 - 1972. Carbon Eleven
Box 7, Folder 8
Experiments 1 to 186
1978 - 1979
Box 8, Folder 1
Experiments 373 to 536
1980 - 1981
Box 8, Folder 2
Experiments 537 to 834
1981 - 1985
Box 8, Folder 3
Experiments 835 to 1159
1985 - 1987
Box 9, Folder 1
Metabolic Scenarios I
1983
Box 9, Folder 2
Methods - Tissue Culture Techniques
1980 - 1981
Box 9, Folder 3
Northern Regional Research Laboratory - Research notes
ca. 1941 - 1945
Box 9, Folder 6
Notebooks 1 - 2
1946 - 1947
Box 10, Folder 3-4
University of Chicago and University of Copenhagen. Notebooks 7 - 10
1948 - 1949
Box 10, Folder 5-6
University of Copenhagen. Notebooks 11 - 12
1949
Box 11, Folder 1-2
Notebooks 13 - 14
1949 - 1951
Box 11, Folder 3-4
Notebooks 18 - 19
1950 - 1952
Box 12, Folder 1-2
Notebooks 23 - 24
1952 - 1953
Box 13, Folder 1-4
Notebooks 34 - 37
1955 - 1957
Box 14, Folder 2-3
Notebooks 43 & 45
1957 - 1958
Box 15, Folder 4
Tufts University and University of California, San Diego. Notebook 84
1965 - 1970
Box 16, Folder 1-2
University of California, San Diego. Notebooks 92 & 95
1970 - 1978
Cation Exchange Resin Derived Leukemia Inhibitor (CERDLIN)
Box 16, Folder 3
Data and graphs
1987 - 1988
Box 16, Folder 4
Elemental analysis
ca. 1988
Box 16, Folder 5, Oversize FB-360-01
Infrared spectra - Oversize
ca. 1987
Box 16, Folder 6, Oversize FB-360-02
Box 16, Folder 7-8, Oversize FB-360-03
Cell Proliferation Project (L-glutamate, Sodium Butyrate, and Quisqualic Acid) - Data, notes and writings by others
1982 - 1986
Box 17, Folder 1
Colchine Effects on [3H] Uridine and [3H] Thymidine - Data tables and graphs
1981
Box 17, Folder 2
Colchine, unidentified data - Data tables, graphs and writings by others
1968
Box 17, Folder 3
Aminoethyl Phosphonate (AEP) Log Cells also Quisqualic Acid and 2-Amino-4-Phosophono-Butyric...
1985
Box 17, Folder 4
BUdR Staining and Effect of Taurine
1985
Box 17, Folder 5
Cytofluorometry (Judy Nordberg)
1985
Box 17, Folder 6
Effects of Aminoethyl Phosphonate (AEP), Quisqualic Acid (QQ), and HC (Elizabeth Crawford)
1985
Box 17, Folder 7
Experiment 908 - Effect of Quisqualic Acid on Cell Cycle of L1210
1986
Box 17, Folder 8
PE, PC and Ethanolamine (Elizabeth Crawford)
1985
Box 17, Folder 9
Quisqualic Acid Experiment (Donna Ruthenmeyer)
ca. 1985
Box 17, Folder 11
Folic Acid - Correspondence, data, graphs, notes, and protocols
1961 - 1969
Box 17, Folder 12
Microtubule Theory of Memory - Notes and writings by others
1974 - 1984
Box 17, Folder 13
Correspondence - William Colwell, Jac L. Crase, Joe DeGraw, James D. Haug, Alton Meister, Charles H. Stanmer, and Yoshi Tsujita
1982 - 1984
Box 17, Folder 15
Miscellaneous - Includes flyers for lectures, technical information of lab equipment and products and other materials
ca. 1978 - 1984
Box 17, Folder 17
Photographs
Ca. 1978 - 1984
Box 17, Folder 18
Starch Gel Electophoresis
undated
Box 17, Folder 19
Writings by others
1955 - 1975
Box 17, Folder 20
Thymidylate Synthetase - Amino acid sequences, correspondence, notes, and writings by others
1971 - 1986
Chemical and Product Information
Box 18, Folder 1
A to Z - Miscellaneous Product Information
1956 - 1987
Box 18, Folder 2
2-Amino-3-Phosphonopropionic Acid
1964 - 1984
Box 18, Folder 3
3T3 Cells - Henry (Enrique) Rozengurt publications
1975 - 1981
Box 18, Folder 4
Bakerbond Chiral Phase Columns - Correspondence, notes and product information
ca. 1984
Box 18, Folder 5
Chemical Library Search Results (American Cancer Society)
1988
Box 18, Folder 6
Chemical requests - Correspondence to or from Friedkin regarding the acquisition of chemicals for research projects
1953 - 1983
Box 18, Folder 7
Difluoromethane-ornithine - Correspondence, notes and reprint
1989
Box 18, Folder 9
Fluoronucleotides
1983 - 1985
Box 18, Folder 10
Hept-6-yne-2,5-diamine
1983 - 1987
Box 18, Folder 11
Hydra-derived Inhibitors - Notes and photocopies of writings by others
1983 - 1985
Box 18, Folder 12
Inhibitory Effects of Aminoethyl Phophonate (AEP) - Correspondence with A. F. Isbell, notes and photocopies of writings by
others
1959 - 1985
Box 18, Folder 13
IR and Molecular Ions - Mass spectra and mass chromatagrams
undated
Box 18, Folder 14, Oversize FB-360-04
Laboratory equipment lists - Oversize
1988
Box 18, Folder 16
Ornithine Decarboxylase - Notes and reprints
1974 - 1988
Box 18, Folder 17
Phthaloylamino Acids - Notes and photocopies of writings by others
1972 - 1983
Box 18, Folder 18
Phosphonopeptides
1978 - 1979
Box 19, Folder 1
Rubidium and Sodium Ions
1975 - 1980
Box 19, Folder 2
Tulp Sedementation Chamber - Graphs, photocopies of writings by others and photographs with negatives
1980 - 1985
Data and Laboratory Techniques
Box 19, Folder 3
2-Amino-4-Phosphono-Butyric Acid (APBA) - Graphs for poster
undated
Box 19, Folder 4-5, Oversize FB-360-05
Aminophosphonocarboxylic Acid Compounds - Nuclear magnetic resonance spectra and correspondence with Jac L. Crase
1983
Box 19, Folder 6
Crawford, Elizabeth, Last experiment - Data, graphs and notes
1987
Box 19, Folder 7
Cronin, Maurin - Data
ca. 1985
Box 19, Folder 8
Diethyl APPA (John Wright) - Data and nuclear magnetic resonance spectra
1979 - 1985
Box 19, Folder 9
Dimethyl Aminoethyl Phosphonate (AEP) Cyanoborohydride Products - Nuclear magnetic resonance spectra
1986
Box 19, Folder 10
Experiments 1058, 1065, 1074, 1079,1098 and 1111 - Data, HPLC printouts and spectrographs
1987
Box 19, Folder 11
Jackson, James - Notes and data
1980 - 1981
Box 19, Folder 12
L1210 +/- BUDr +/- Aminoethyl Phosphonate (Elizabeth Crawford) - Data, graphs and notes
1985
Box 19, Folder 13
Organic Synthesis - Notes and photocopies of writings by others
1941 - 1987
Box 19, Folder 14
Organic Synthesis Techniques (Frank H. Stodola) - Notes and reprints of writings by others
1942 - 1945
Box 19, Folder 15
Plante (Larry) Compounds - Summary
undated
Box 19, Folder 16
Positron Emission Tomography - Photocopies and reprints of writings by others
1948 - 1987
Box 19, Folder 17
Procedure for Phosphate Determination
1977
Box 19, Folder 18
Protocol for the Prepartion of 3T3 Cell Extracts
ca. 1979
Box 19, Folder 19
Proton Magnetic Resonance - Notes and photocopies of writings by others
1975 - 1988
Box 19, Folder 20
Redistilled Water Room at the Washington University School of Medicine - Drawing and photograph of redistillation apparatus
1958
Box 19, Folder 21
Resolution of Phosphono Compounds - Notes and photocopies of writings by others
1979 - 1984
Box 19, Folder 22
Ruthemeyer, Donna - Data Summary
1985
Box 19, Folder 23
Scintigraphy - Graphs
1977
Box 19, Folder 24
Thiouracil Deoxyriboside Crystals
ca. 1954
Box 19, Folder 25
Use of Nuclear Magnetic Resonance Instrument at Brookhaven National Laboratory - Notes
1987
Box 19, Folder 26
X-ray Diffraction of Synthetic and Natural Thymidine - Data and x-ray images
1953
Box 19, Folder 27
Unidentified research images - Photographs and glass slide from Washington University Department of Illustrations
undated
Box 20, Folder 1
Unidentified research materials - Chromatographs and x-ray films
1977
Box 20, Folder 3-25, Oversize FB-360-06
Box 21, Folder 1-12, Oversize FB-360-07-09
Box 21, Folder 13
Unidentified negatives of figures
undated
Box 21, Folder 14, Oversize FB-282-10
Unidentified figures - Oversize drawings and photoreproductions
undated
Box 21, Folder 15
Announcements - Miscellaneous
1957 - 1985
Box 21, Folder 16
Studies of Photosynthesis with Isotopes (Denmark) - Lecture typescript with figures
1949
Box 21, Folder 17
Desoxyranthosine - American Chemical Society (Chicago). Typescript
1950
Box 21, Folder 18
Enzymatic Synthesis of Thymidine - Lecture schedule, manuscript, figures, and reprints of writings by others
1951
Box 21, Folder 19
Synthesis of Thymidine - Manuscript
1951
Box 21, Folder 20
Azguania Nucleosides - Paper presented at the Federation Meeting. Manuscript
1952
Box 21, Folder 21
[Title unreadable] - Typescript
1952
Box 21, Folder 22
Untitled - Atlantic City lecture. Manuscript with figures
1962
Box 21, Folder 23
Biochemical Role of Vitamin B12 in Cellular Proliferation - Typescript of a lecture given by Friedkin at the IX Congresso
da Sociedade Europeia de Hematologia
1963
Box 21, Folder 24
Morris Friedkin, et. al. Two-Enzyme Screen for the Design of New Folate Antagonists - Typescript
ca. 1963
Box 21, Folder 25
Role of Folic Acid in Malaria - Manuscript and typescript
1968
Box 21, Folder 26
Structure and Function of Microtubules (Harvard University) - Notecards
1969
Box 21, Folder 27
Study of Folate Analogs (Faculty Seminar at UCSD) - Announcement and manuscript
1970
Box 21, Folder 28
Untitled (Hadassah Medical School Seminar) - Manuscript
1978
Box 21, Folder 29
Colchine Seminar - Manuscript
1980
Box 21, Folder 30
Role of Microtubules - Announcement and manuscript
1980
Box 21, Folder 31
Untitled lecture notes
ca. 1992
Box 21, Folder 32
Ancient History of Thymidylate Synthetase - Typescript
undated
Box 21, Folder 33
Use of Enzymens in the Design of New Drugs - Manuscript
undated
Box 21, Folder 34
Untitled lecture on cytoplasmic microtubules - Notecards
undated
Unnumbered Publications and Unpublished Writings
Box 21, Folder 35-36, Oversize FB-360-10
Attempted Block of De Novo Serine Biosynthesis by Inhibition of Phosphoserine Phosphatase
1983
Box 22, Folder 1
Morris Friedkin, et. al. Cell Cycle of L1210 Leukemia Cells is Blocked at G2/M by a Water-Soluable Polymer...
1988
Box 22, Folder 3
Class of 1968 - Tufts University School of Medicine Yearbook message
1968
Box 22, Folder 4
Conservation of Form in Water
1960
Box 22, Folder 5
Contrasting Styles with the Same Objective: Impressing Students with the Wonder of Life
1975
Box 22, Folder 6
Crystalline Desoxyribose-1-Phosphate
ca. 1949
Box 22, Folder 7
Effects of 2micromolar Colchicine and 100 Ng/Ml Insulin on Cumulative Uridine Uptake
undated
Box 22, Folder 8
Forty Years - Manuscript of a timeline of Friedkin's major research interests
ca. 1982
Box 22, Folder 9
Friedkin, Morris, et. al. Tritium Isotope Effect During the Enzymic Synthesis of Thymidylate
ca. 1967
Box 22, Folder 10-12, Oversize FB-360-11
Friedkin, Morris and Leslie Wilson. Microtubule Theory of Memory
1968
Box 22, Folder 14
Pharmacology - Tufts University School of Medicine Yearbook message
1961
Box 22, Folder 15
Preparation of Carbon-11 Labelled Thymidine
ca. 1962
Box 22, Folder 16
Morris Friedkin, et. al. Process for the Production of 5'-Deoxy-5-[18F] Fluoridine - Patent application and correspondence
with Brookhaven National Laboratory
1983
Box 22, Folder 17
Morris Friedkin and William Schwartz. Projection of Health Science Research Needs for the Tufts-New...
ca. 1958 - 1969
Box 22, Folder 18
Revolution in Pharmacology
1960
Box 22, Folder 19
Morris Friedkin and Vincent Reid. Role of Folic Acid in Malaria
1967
Box 22, Folder 20
Rolling in Something Ripe...
1989
Box 22, Folder 21-23, Oversize FB-360-12
Studies on Aerobic Phosphorylation - Ph. D. dissertation
1947 - 1948
Box 23, Folder 1
Suggestions for Noah Freidkin (son)
1988
Box 23, Folder 2
Two-Enzyme Screen for the Design of New Folate Antagonists
1963
TEACHING AND ADMINISTRATIVE MATERIALS
Washington University School of Medicine
Box 23, Folder 3
Relationship of Vitamin B12 and the Deoxyribosides - Manuscript of a lecture for a biochemistry seminar
1949
Box 23, Folder 4
Quantitative Methods in Medicine - Course handouts, lecture manuscripts, examinations, and correspondence
1950 - 1958
Box 23, Folder 5
Physiology Seminar, B12 and Intrinsic Factors - Notecards and lecture manuscript
1951
Box 23, Folder 6
Washington University apartment lease
1950
Box 23, Folder 7
New Cold Room at the Washington University School of Medicine
1958
Tufts University School of Medicine
Box 23, Folder 8
Elementary Statistical Analysis for Use in Pharmacology - Course handouts and lecture manuscripts
1960
Box 23, Folder 9
Biology of Macromolecules Course: Learning and Memory - Lecture manuscript, reference list and reprints
1966
Box 23, Folder 10
Introduction to Biochemistry - Course handouts and lecture manuscript
1967
Box 23, Folder 11
Administrative documents - Includes Department of Pharmacology documents, Department of Biochemistry documents, A. Warren
Stearns building information, and documents regarding Dean Haymen's retirement
1958 - 1969
Box 23, Folder 12
Nine Good Years - This document is a collection of articles produced by members of the Department of Pharmacology at Tufts
University School of Medicine during Friedkin's time as chair of the department
1958 - 1967
Box 24, Folder 3
Tufts-New England Medical Center - Newspaper clippings
1966
Box 24, Folder 5
Includes Tufts University Department of Biochemistry floor plan, Tufts University Department of Pharmacology floor plan, and
other unidentified floor plans
1967
Box 24, Folder 6, Oversize MC-154-04
Includes Tufts University Department of Biochemistry floor plan, blueprint of floor plan for Tufts College Medical and Dental
School (194?), and other unidentified laboratory or building floor plans
1940 - 1967
Box 24, Folder 7
Chemistry 219, Folic Acid Lectures - Lecture manuscripts, lecture schedule, course handout, and examination
1976
Box 24, Folder 8
Chemistry 269, Folic Acid Lectures - Lecture manuscripts
1970
Box 24, Folder 9
Carbon Dioxide History for Introduction to Biochemistry 105R - Lecture manuscript
1976 - 1978
Box 24, Folder 10
Suggestions for the Development of the Biomedical Program at San Diego - Manuscript, notes, correspondence, and newspaper
clippings
1964
Box 24, Folder 11
Provost of Revelle College - Includes notes, typescripts, and letters to parents from the Provost
1974 - 1976
Box 24, Folder 12
Investigation of scientific misconduct - Includes Morris Friedkin and Suresh Subramani's notes on interviews with parties
involved, photocopy of original complaint, correspondence and other related materials
1992
Conditions Governing Access note
Restrictions Apply
Box 25, Folder 1
A - Z - Miscellaneous
1936 - 1986
Box 25, Folder 2
Bobbs-Merrill Reprint Series in the Life Sciences
1952 - 1963
Box 25, Folder 3
Drew, Ruth M. and Robert B. Painter. "Action of Tritiated Thymidine on the Clonal Growth of Mammalian Cells"
1958
Box 25, Folder 4
Dicker, Phillip and Enrique Rozengurt. "Synergistic Stimulation of Early Events and DNA Synthesis by..."
undated
Box 25, Folder 5
"Formal Theory of Social Control"
undated
Box 25, Folder 6
"Horizons of Observability and the Limits of Informal Control in Intraorganizational..."
1983
Box 25, Folder 7
"On the Origins and Prevalence of the Incest Taboo"
undated
Box 25, Folder 8
Hanke, Martin E.
Laboratory and Classroom Outline for Hydrogen Ion and Oxidation-Reduction Potentials
1939
Box 25, Folder 9, Oversize FB-360-13
Huang, Leaf and Richard E. Pagano. "Interaction of Phospholipid Vesicles with Cultured Mammalian Cells"
1975
Box 25, Folder 10
Hughes, W. L. "Chromosomal Replication and the Dynamics of Cellular Proliferation - Some Autoradiographic..."
undated
Box 25, Folder 11
Levinson, Joel. "Photography of Anthony Friedkin"
1980
Box 25, Folder 12
Lomax, Nancita R. and V. L. Narayanan. "Chemical Structures of Interest to the Division of Cancer..."
1983
Box 25, Folder 13
Mackay, A. F. "Diazohydrocarbons"
1950
Box 25, Folder 14
Painter, R. B., et al. "Distribution of Tritium-labelled Thymidine in Escherichia Coli During Cell..."
1958
Box 25, Folder 15
Robertson, J. S. and W. L. Hughes. "Intra-Nuclear Irradiation with Tritium-labeled Thymidine"
undated
Box 25, Folder 16
Sreevalson, T., et al. "Differential Effect of Interferon on DNA Synthesis 2-deoxyglucose Uptake and..."
undated
Box 25, Folder 17
Wilson, Leslie. "Grasshopper Nueroblast Report."
1965
Box 25, Folder 18
Yorek, Mark A., et al. "Effect of Ethanolamine on Choline Uptake and Incorporation into..."
undated
Box 25, Folder 19
IX Congresso da Sociedade Europeia de Hematologia - Conference program, correspondence and notes
1963
Box 25, Folder 20
CERDLIN - A Potential Cancer Chemotherapeutic Agent Derived from Commercial Dowx 50 (Cation Exchange Resin) - Record of invention
and correspondence
1986 - 1987
Box 25, Folder 21
Gordon Research Conferences - Includes conference booklets with notes
1966 - 1968
Box 25, Folder 22
International Convention of Biochemists (Bangalore) - Correspondence, convention materials and abstract of folic acid in malaria
research
1967
Box 26, Folder 1
Malaria Conference (Walter Reed Army Institute of Research) - Correspondence, conference schedule and notes taken by Friedkin
at the conference
1968
Box 26, Folder 2
Kaplan, Nathan O. Memorial materials - Correspondence and reprints of memorial articles from
Analytical Chemistry
1986 - 1987
Box 26, Folder 3
Minutes of the Screening Committee for the California Division (American Cancer Society)
1978
Box 26, Folder 4
Newspaper clippings concerning others
1965 - 1986
Box 26, Folder 5
Oregon State Seminar - Notes and correspondence
1973
Box 26, Folder 6
Review of Graduate Pharmacology Program at the University of California, San Francisco - Correspondence, program guides and
typescripts of review
1989
Box 26, Folder 7
Seventh International Congress of Biochemistry (Tokyo) - Correspondence and conference schedule
1967
Box 26, Folder 8
Slides - Miscellaneous
undated
Box 26, Folder 9
Vietnam - Correspondence
1966
ORIGINALS OF PRESERVATION PHOTOCOPIES
Box 26, Folder 10
Originals of preservation photocopies