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Nelson (William James) Laboratory, Records
SC1453  
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Collection Overview
 
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Description
Collection consists of lab research notes.
Background
The Nelson lab's research seeks to understand how cell interactions specify the correct cellular organization of complex tissues, and how structurally and functionally different plasma membrane domains are assembled and tailored to specific tissue and organ functions. They take multi-faceted experimental approaches to these problems including: biophysical methods using single molecules; in vitro reconstitution with purified proteins; state-of-the art live cell fluorescence microscopy; and analysis of abnormalities in cellular and subcellular organization in disease states. They focus on experimentally tractable model cell systems that can be examined mechanistically by biochemical and cell biological approaches, although they are now working with more complex developmental systems including Zebrafish and Dictyostelium. Their research has provided detailed molecular insights into protein-protein interactions and mechanisms that link cell-cell adhesion to the functional differentiation of cells. https://biox.stanford.edu/people/w-james-nelson
Extent
10.5 Linear Feet
Restrictions
All requests to reproduce, publish, quote from, or otherwise use collection materials must be submitted in writing to the Head of Special Collections and University Archives, Stanford University Libraries, Stanford, California 94304-6064. Consent is given on behalf of Special Collections as the owner of the physical items and is not intended to include or imply permission from the copyright owner. Such permission must be obtained from the copyright owner, heir(s) or assigns. Restrictions also apply to digital representations of the original materials. Use of digital files is restricted to research and educational purposes.
Availability
Materials are open for research use. Audio-visual materials are not available in original format, and must be reformatted to a digital use copy.