Guide to the Paul Berg Papers SC0358
Note
| 1952-1954: | American Cancer Society fellow, Institute in Copenhagen and Washington University School of medicine. His work was concerned with clarifying how the master substances of heredity, DNA, transfers its genetic information to analogous molecules, known as RNA, which serve as templates for making proteins. |
| 1954: | Scholar in cancer research at University of Washington. His work on the genetic apparatus that directs the synthesis of protein earned Berg the Eli Lilly award in biochemistry in 1959. |
| 1960: | Stanford School of Medicine, associate professor of biochemistry and until 1967 continued work on protein synthesis. All this work was based on bacterial cells, but in 1967, he decided to do research on animal cells, taking a year's leave. He worked at the Salk Institute on tumor viruses. |
| 1970: | By about 1970, Berg and his associates began to think how they might use tumor viruses to bring new genes to animal cells - "man-made living matter" or "engineered a new genetic molecule." This raised the question of ethics, so, in 1973, they stopped experimentation. |
| 1975: | National Academy of Sciences sponsors meeting, chaired by Berg, whose purpose is to conduct a survey of potential hazards involved (Asilomar). This resulted in a set of recommendations to establish guidelines to put certain constraints on experiments; these were organized by the NIH and are used as guidelines today. |
| 1980: | Berg was awarded the Nobel Prize in chemistry for "fundamental studies of the biochemistry of nucleic acids with particular regard to recombinant DNA." Berg was also responsible for shaping "policy" for dealing with possible risks of recombinant DNA research. |
| 1984: | Appointed director of Stanford University's Center for Molecular and Genetic Medicine. |
Subjects and Indexing Terms
Correspondence Series 1 1959-1985
Correspondence A - J 1959 - 1962
Correspondence K - Z 1959 - 1962
Correspondence 1962 - 1964
Correspondence A - B 1965 - 1966
Correspondence C - D 1965 - 1966
Correspondence E - G 1965 - 1966
Correspondence H - K 1965 - 1966
Correspondence L - N 1965 - 1966
Correspondence O - R 1965 - 1966
Correspondence S 1965 - 1966
Correspondence T - Z 1965 - 1966
Correspondence on Positions 1959 - 1967
Comm. on Medical Education - Drafts and reports
NAS - letters of congratulations, 1966
Gordan Conference (Nucleic Acids), 1966
NIH Study Section - Physiological Chemistry, corresp. 1964 - 1965
NIH Study Section, correspondence 1964 - 1965
Comm. on Public Exercises & Public Events 1968 - 1969
University Public Health Committee corresp., 1968 - 1969
Comm. on Committees (Proposed Research) corresp., 1968 - 1969
NAS - National Research Council, correspondence, 1966
NAS - Life Sciences panel, correspondence, 1966
NAS, correspondence, 1966
Journal of Biological Chemistry, Publications Committee, correspondence, 1965 - 1967
Journal of Molecular Biology, correspondence, 1967 - 1970
Orbit correspondence, 1969
NAS, correspondence, 1967 - 1968
Post-doctoral applications, rejected 1969
Correspondence A - H 1969
Correspondence I - O 1969
Correspondence P - Z 1969
Correspondence A - H 1970
Correspondence I - O 1970
Correspondence P -Z 1970
Correspondence, Chron file, 1970
Correspondence, Chron file, January - June 1971
Correspondence, Chron file, July -November 1971
Correspondence A - L 1972
Correspondence M - Z 1972
Correspondence, Chron file, 1973
Correspondence A - K 1973
Correspondence M - Z 1973
Correspondence, Faculty/Technical Positions, 1973
Correspondence post-doc rejects, 1973
Correspondence, Chron file, 1974
Correspondence A - N 1974
Correspondence N - Z 1974
Correspondence, Faculty positions, 1974
Correspondence A - Z 1975
Correspondence, post-doc rejects, 1974
Correspondence NSF Human Cell Program 1971 - 1974
Correspondence NSF Human Biology Steering Comm. 1970 - 1976
Correspondence "President's Biomedical Research Panel - Palade's Cluster" 1975
Correspondence Jane Coffin Childs Fund, 1972
Correspondence, University Comm. on Research Policy 1972 -1976
Correspondence with Rich [Med. School Dean] 1973
Correspondence Jane Coffin Childs April 1973
Correspondence Jane Coffin Childs meeting, 1974 Oct. 4
Correspondence Jane C. Childs Spring Meeting 1975
Correspondence, Council on Analysis and Projection
Correspondence, Council on Analysis and Projection
Scientific American
National Medal of Science, nomination A. Kornberg, 1969
Correspondence A - C 1976 - 1978
Correspondence D - G 1976 - 1978
Correspondence H - L 1976 - 1978
Correspondence M - Q 1976 - 1978
Correspondence R - T 1976 - 1978
Correspondence U - W 1976 - 1978
Correspondence A - C 1978 - 1979
Correspondence D - F 1978 - 1979
Correspondence G - I 1978 - 1979
Correspondence J - N 1978 - 1979
Correspondence R 1978 - 1979
Correspondence S - Z 1978 - 1979
Letters of Recommendation, A - D 1973 - 1976
Letters of Recommendation, E - H 1973 - 1976
Letters of Recommendation, J - O 1976 - 1977
Letters of Recommendation, R - Z 1972 - 1978
Post-doc application rejects, Jan - June 1979
Post-doc application rejects, July - December 1979
Travel Correspondence - lectures/symposia 1982 - 1985
Travel Correspondence - lectures/symposia 1980 - 1981
Research lab notebooks Series 2 1953-1986
Paul Berg:
Methods (Salk Institute) 1967/68
Mut 51 - 78 (Salk Institute) 1967
RNA - Isolation from Tissue Cultures 1967
PY (P.B.) (La Jolla) 1967
Mut 79 - 141 (Salk Institute) 1968
Mut 142 - 225 (Salk Institute) 1968/69
AA - Incorporation (Amino acids ?) 1968
EM (Electron Microscopy) of TSA viral DNA's 1968
Nicking-Enzyme (F.C.) 1969
Nicking-Enzyme II (F.C.) 1969
Virus I V-1 to V-57 (M.D.) 1969/71
DNA-Synthesis in Nuclei (M. D.) 1970
c-RNA-Synthesis in vitro (Py) 1970/71
Cot 1 1970/71
Hin Fragments (SV 40) 1972
Cot 2 1972
Acetate III, 1954-55
Acetate IV, Part 1, 1955-56
Acetate IV, part 2, 1955-56
Synthesis of amino acyl adenylates, 1956
Synthesis and study of adenyl-amino acids 1956 Sept. - 1957 May
Amino acid incorporatio into RNA, I, 1957 May - 1958 July
Amino acid incorporatio into RNA, II, 1958 July - 1959 April
Purification of e. coli RNase 1958-59
Purification of RNA, 1959 Jan. - May
Acetate incorporation 1964 Mar. 18 - 1964 June 2
Acetate incorporation 1964 June 23- Sept. 22
Purification of amino acid activating enzymes 1958 June - October
Methionyl Act-Enz (Yeast) I, 1955-56
Unlabeled [Acetate II ?], 1954
Acetate I, 1953-54
GLy-RNA Synthetase I, 1965 July 11 - 1966 Aug. 26
GLy-RNA Synthetase II, 1966 Aug. 25 -1967 Apr. 12
GLy-RNA Synthetase III, 1967 July 14 - Aug. 14
Prep. & triphosphates
Growth curves 1966 Sept. 19 - 1967 July 6
Preparation of ARPP+P+, 1964
Vancouver 1956
Paris experiments, 1961
Polyama Cot Data
Science article, 1968
General thoughts on suppression
Notes for paper on level of suppression
Mechanism of missense suppression
Dieckmann/Berg:
COT II A 1972
COTs for publication
SV Plaque Morphology Mutants 1973
Isolation of SV 40 Complex 1973
SV 40 Mutants (Plaque Assays) 1974/1975
SV 40 Mu, Dn'ase (Mutants M. D.) 1975/1976
SV 40 Mu Late and Early (dl 861) 1975/1976
SV 40 Mu, Complementation (Mutant Characterization Complementation) 1976
Replication Ori 1976
SV 40 Mu, Hpall, Early and Late 1976
Lagerkrist 1977
Plasminogen Activator 1977/1978
Tag Function (Doefler), Dieckmann 1978
Restriction Mapping of Yeast t-RNA Inserts 1978
beta Globin, 2kb in SV 1979
alpha- and beta-Globin in SV 1979
Berg/Dieckmann/Hoshi:
Mouse Embryos 1980
NIH Guidelines 1980, 1982, 1986
TC June Hoshi 1970
[Untitled] 1974/75
[Untitled] 1976/77
[Untitled] 1978 to 1980
[Untitled] 1980/81
[Untitled] 1982 to 1986
Plaque Assays 1972 to 1979
Notebooks by others:
Peter Powell's paper and notes
Jack Preiss: ACC - adding enzyme, Book 1, 1959-60
Jack Preiss: ACC - adding enzyme, Book 2, 1959-60
Jack Preiss: ACC - adding enzyme, Book 3, 1959-60
Jack Preiss: ACC-RNA end group identification
Jack Preiss: E. Coli Lysates, 1958 Sept. - 1959 May
Fred Bergmann notebooks
Recombinant DNA Series 3 1973-1977
History 1973 - 1977
Correspondence, A - H (pre Asilomar), 1974 - 1975
Correspondence, I - R (pre Asilomar), 1974 - 1975
Correspondence, S - Z (pre Asilomar), 1974 - 1975
Asilomar Administrative Materials (conference coordinator)
Asilomar Meeting Material
Final Report (originals)
Asilomar statement documents
NAS Final Report (Working Papers)
Correspondence (post Asilomar) 1975
Correspondence (post Asilomar) 1976 - 1977
Correspondence (pre Asilomar)
Papers 1973 - 1977
News articles prior to 1974
News articles 1974
News articles 1975
News articles 1977
Recombinant DNA Controversy at Ann Arbor, Michigan
NIH Director's Advisory Committee Meeting, Feb. 9 -10, 1976
Kennedy Hearings Cambridge Controversy
Non-NIH Guidelines (USA & abroad)
Index, RDR Reference lists, RDR Master of selected articles
Correspondence (MIT meeting) 1974
Manuscripts 1974 - 1977
Recombinant DNA Research Vol. 1, US Dept HEW, NIH August 1976:
Draft: Environmental Impact Statement Guidelines for research involving Recombinant DNA Molecules 1976 Aug. 19
NIH Recombinant DNA research minutes/meeting reports etc., 1976 - 1977
Cambridge City Council Matters
Published Reactions to NIH Guidelines on RD Research
Reply to Chargaff letter
WHO on Recombinant DNA Molecules
Germ warfare correspondence
"Genetic Scientists: Facing the Mutant Microbe," Rolling Stone, June 19, 1975
"Genetisk Manipulation," INGENIOREN, Sept. 22, 1977
DNA: meetings/hearings/publications
DNA: essays
Recombinant DNA articles/clippings, 1976 - 1977
DNA: copies of Berg's Senate Testimony
The Salk Institute Series 4 1972 - 1976
CV of Personnel for Dr. Paul Berg
Salk Institute: Correspondence, Holley's Lab, Salk Personnel listing
Banbury Center - Cold Spring Harbor Lab, (Initial attempts at Berg et al II - corresp -, Bio-hazards of Viruses) ca. 1977
Administrative files Series 5 1968-1984
Manuscript - Biofuture: Confronting the Genetic Era,pp. 1 - 465, by Burke K. Zimmerman, n.d.
Grant files ca. 1974 - 1982
Reprints
Faculty applications, post-doc applications
Staff Meeting Minutes 1969 July 1
Faculty Meetings - Agendas - Minutes, 1968 - 1969
Faculty Senate - Agenda - Minutes, Jan - Dec 1971
Faculty Meeting, 1971 - 1972
Faculty Meeting, 1972 - 1973
Faculty Minutes and Memos 1979 Sept. - 1980 Aug.
Faculty Minutes and Memos 1979 Sept. - 1980 Aug.
Faculty Minutes and Memos 1980 Sept. - 1982 Aug.
Executive Committee Dec 1971 - March 1973
Executive Committee April - Dec 1973
Weekly-Minder 1971 - 1972
Weekly-Minder 1972 - 1973
Hearings/Committees on Recombinant DNA (US Senate/State legislatures) 1976 - 1977
Misc. Grant files and Disk files
Post doc files 1981-1984
Trip Files: lectures/symposia, 1975 - 1980
Trip files/lectures/symposia
National Academy of Sciences Council Meeting 1980 Oct. 26
National Academy of Sciences
Congressional Hearing 1981 May 6
Manuscript Reviews completed
Potential post-doctoral fellows
Seminar Invitations declined
Misc. check requests
Medical School Biohazards Committee
Audio Visual Materials Series 6
Illustrations for publications
Dr. Berg Seminar, Part I and Part II, 1987 Nov. 11
Berg "Genetic Engineering: Challenge and Responsibility," 1975 Mar. 7
Dr. Berg, "Dissections and Reconstruction of the SV40 Genome," NIH Lecture 1976 Nov. 17
William H. Stein, lecture at Rockefeller University, 1984 Mar. 16
Additional Material Accession ARCH-1991-020
News clippings on DNA research, 1975 - 1976
Business correspondence, 1975 - 1976
Personal correspondence, re: Asilomar, 1975 - 1976
Comments and revisions of Asilomar Report: drafts and letter, 1975
News clippings on Ethics and Guidelines for Genetic Research, 1975 - 1976
Essays on the ethics of science/DNA research:
The Benefits of Saying YES! by Paul Ehrlich (1975)
Toward an International Ethic of Science by Sergent Shriver (1975)
Untitled - final version of the bioethics story with letter to Berg from S. F. Moran (1975)
Scientists with a Secret" by Spencer R. Weart (1976)
Memos and info on conferences: Asilomar Conference - programs, roster, memo; Joint MRC/ARC/SRC Conference on Recombinant DNA, (1975)
International Conference on Recombinant DNA Molecules: memos, contract and budget
ASILOMAR Conference: "Summary Statement of the Asilomar Conference on Recombinant DNA Molecules" manuscript and "Report of the Organizing Committee of the Asilomar. . ." drafts
DNA Testimony to Senate Committee, incoming and outgoing correspondence, testimony by Berg for the Subcommittee on Science, Technology, and Space 1977
Recombinant DNA Correspondence, 1979 - 1991
Addresses/Conferees
Recombinant DNA: correspondence and related matters, 1976 - 1980
Notebook: misc. letters and reports on recombinant DNA and conferences, NIH Advisory Committee, Environmental Impact Statement
Notebook, Current Guidelines for Research in Recombinant DNA molecules, Members of the Recombinant DNA Program Advisory Committee - memos, letters, drafts, minutes 1975
Additional Material Accession ARCH-2001-092
Office files
Office files
Binder
David Singer
AMBO/AMBL
Engelhardt Institute July 1999
Tokyo Univ. Bio Inauguration
Lasker Foundation
Glenn Foundation
SKB proposals
Genes & Genomes: Correspondence
Exploring: Early correspondence
Dealing with Genes: Correspondence
Beckman Center Newsletters
Fellowship support
Possible students
Job applicants
Research Students: Stanford policies
Others' lab students: recs, nominations
Postdocs: general
Postdoc/grad student status
Postdocs accepted
Postdocs rejected
Students accepted
NIH 13235:
1996-7 NIH Renewal GM 13235
1995-6 NIH Renewal GM 13235
7/87-6/92 NIH Renewal GM 13235
1989-9 NIH ROI 13235-22
Aging Grant:
1995-6 Aging Grant renewal
1994-5 Aging Grant renewal
1993-4 Aging Grant renewal
1992-3 Aging Grant renewal
1990 Aging Grant
1990 Aging Grant binder
NIH AIDS: Davis/Berg AIDS grant
CMB Grant
Dzau Cardiovascular Training Grant
Training Grant
Bergfest
IOM Patent Study Group
cDNA Patent Letter
Trip files, 1987-1990
Trip files, 1990-1993
Reprints 1951-79
Reprints 1980-2000
Course materials:
Path to Code
Biochem 202 (1990-1997)
Human Bio 1993
Hurlbut class
DB229 Molec. & Genetic Medicine
Medicine 229
Cell Sciences course
ASCB 1995
ASCB 1997
CASBS
Chulabhorn Research Institute
Rep. George Brown correspondence
Human Genome Program Advisory Cte.
Gerontological Society of American
CA Academic Standards Commission
PB Personal
SF United School District Advis. Council
NFBR 194-5
NFBR 1996 (2 folders)
NFBR 1997
Mabel Beckman
Beckman F GAC 1990-1997
French Academy of Science
5 binders Beckman design corrections
Beckman Fundraising 1980-1989:
Fundraising correspondence 1980-1989
Crocker proposal
Genentech
Communications with Kennedy 1984
Communications with Crowley 1984
Communications with Purpura 1984
Discussions with Dean 1986
CMGM Fundraising correspondence
Funding for CMGM Center
Academic Plan for CMGM 8/84
Original Program in Medical Genetics 1981
CMGM Search Committees
Center for Molec. & Genetic Med. Committee
HHMI Policies for Investigators
Relations between HHMI and CMGM
Hughes Institute materials
Correspondence with Purnell Choppin
A. Beckman Matters 9/84
Second Appeal to Beckman
Fairchild Foundation
Markey Foundation
Markey Proposal II
Mather Foundation matters
Dealings with SKB
The SKB Agreement
Correspondence with Wendt & Dealings with SKB gifts
George & Camilla Smith Foundation
Zaffaroni file
MGM 5/10/85
Scientific Symposium 20 Anniversary 3/27-28/80
PPG Discussions
Sandoz
Dupont file
Steve Jobs
Bob Swanson – Genentech
Beckman Symposium 10/17/85
The Beckman Naming Occasion
General Fundraising
Correspondence with Jack Whitehead
Communications with Mrt. Li Ka-shing
Gerson Bakar
David Blech
Syntex – Rosenkranz and Allen
Bob Noyce file
Colton
Brook Byers Foundation
Ron Cape
Weingart Foundation
[unlisted folders]
[NIH Grant - unlisted folders]
Program in Molec. & Genetic Medicine members
AAAS
Beckman Symposium 10/12/85
Erik Boye
Karol Taylor
Elman Walde
Michael O'Donnell
David Bramhill
Roger Kasken
James Flynn Jr.
Kazuhisa Sekimizu
Fellowship Programs
Hisaji Maki
Kornberg Symposium 5/88 (2)
Beckman Management Group
1991 Markey Trust Proposal
Industrial Affliliates
Wm. Freeman & Co.
LSRF
NSF
Nobel Committee (3)
Franco-Amer Assn for Fetal Med
Pre-'89 Correspondence F, G, M
Pre-'89 Correspondence A-E, H-L, N-Z
Rockefeller Board
Trip files 1996
Trip files 1996-97
Videos of talks at The Welch Foundation Chemical Conference 1993
Man's tie with A. Beckman image
Course materials, 1996
Trip files 1994
Trip files 1995-97
Videos
Unlisted files
Videos
Grad students
Arndt- John, Donna
Addresses of former group members
Bretsdev, Mark
Bnaerjee, Ronadip
Mantevil-Brutlag, Simone
Buchman, Andy
Barsoum, James
Baldwin, Anne Norris
Clanedar, Rich
Clark, Steve
Carbon, John
Canaani, Dan
Chamberlin, Michael
Chambers, Ian Paul
Chu, Gilbert
Cuzin, Francois
Cruz, Myra
Cole, Charles
Dieckmann, Marianne
Diaz, Elva
DePamphilis, Mel
Doerfler, Walter
Donoho, Greg
Dulbecco, Renato
Arnanz, Montserrat
Firmenich, Antoine
Folk,
Fromm, Mike
Gassmann, Max
Garren, Ron
Geller, Al
Goff, Steve
Hacohen, Nir
Hayakawa, Dr. Hiroshi
Hays, Sharon, 2 folders
Higgins, Mark
Hofstetler, Hans
Hill, Charles
Holland, Eric
Hsu, Ming-ta
Howard, Bruce
Igarashi, Koiche
Iaccarino, M.
Jessberger, Rolf
Kadesh, Tom
Unlabeled folder with photos
Jasin, Maria (no label on folder)
Konner, Jason
Kirk-Felton, Libby
Kawakami, Christine
Kornberg, Roger
Kroeger, Chris
Krushelnycky, Bohdan
Lagerkvist
Lewis, Susanna (2 folders)
Littauer, Uriel (2 folders)
Muenck, Karl
Luria, Sylvie
Magnusson, Govan
Margolskee, Bob
Mark, David
McPhail, Mike
Mertz, Janet
Morrow, John
Morrison, Sherie
Mulligan, Richard
Mukherjee, Siddhartha
Nichols, J. F.
Nordloh
Ogunmola, Prof G. B.
Ofengand
Peabody, Dave
Ozawa, Clare
Ostrem, Dennis
Okayama, Hiroto
Primakoff, Paul
Pontius, Brian
Reichardt, Jurgen
Rathmell, Kim
Remtulla, Ally
Reichard, Peter
Schreiber, Edgar
Rigby, Peter
Scott, Christopher (no folder)
Shenk, Tom
Sklar, Jeff
Shishido, Kazuo (2 folders)
Smith, Andrew – 2 folders
Southern, Peter
Soll, Larry
Smith, Brad
Strehlow, David
Stuhlmann, Heidi
Symans, R. H.
Suresh, Subramani
Theland, Lars
Yarus, M
Tomasson, Mike
Wilson, John
Walberg, Mark
Villareal, L.
Trager, Jacqueline
Yamiu
White, Ty
Wood, B.W.
Wong, Brian
You, Ji Chang
Zierler, Helge (2 folders)
Zemelman, Boris
Strain notebooks – 4 volumes with sections labeled with individual (student?) names
Berg Reprints Ca. 1979-1996
Berg Reprints
External Science Advisory Committee 1992
Univ Colorado Health Science Center 1992
Joklik Symposium 1992
Beckman Grants Advisory Committee 1992
Annenberg Symposium 1992
Rockefeller Board 1992
Stanford Alumni (2 folders) 1992
Juan March Foundation 1992
Mel Cohn Symposium 1992
Weizmann Dinner 1992
Yanofsky Award 1992
Cornell keynote, NYC n.d.
Personal correspondence
Biochem 202 extra handouts
CMGM Executive Committee
minutes 1982-1988
minutes 1982-87
Directorate, minutes 1982-84
PMGM Seminars 1995/96
Spectrum nametags – no folder
Biological Sciences
Developmental Biology
Cancer Biology
Spectrum Photos- envelope no folder
Spectrum 1994
Spectrum Expenses
Spectrum Expenses – unfoldered material
Spectrum program
Binder – PMGM New Faculty Recruitment
Biochem Department files—may not have listed every file
Biochemisry Affiliate Program
Biochem Faculty reports
Bichem Founders Fund
Biochem general
Lab spaces
Grad admission interviews
Heller lecture
Stanford Art Committee
Stanford Center for Biomedical Ethics
Biotechnology-Law Course
Cahill Chair
Stanford Clinical Cancer Center
Consulting/Conflict of Interest matters
Dean Funding
Dean’s Task Force on PhD training
Faculty Campaign Planning Committee
Stanford Gene therapy Task Force
Indirect Cost Debate
LCME Accrediation
Lohrlein, Christine
Millenial Forum
Stanford –NIH
Videos and books
Affiliation files
Service with non-Stanford organizations, foundations, etc.
Genome testimony files
public and non-public images and metadata for the Profiles in Science site on Paul Berg [computer files] Accession ARCH-2009-127