Scope and Content
Organization and Arrangement
Title: Isaac Harary Papers,
Date (inclusive): 1950-1987
Collection number: 372
Creator: Harary, Isaac
9 cartons (9 linear ft.)
University of California, Los Angeles. Library. Department of Special Collections.
Los Angeles, California 90095-1575
Abstract: Isaac Harary (1923- ) was born in New York City, New York. He was an assistant clinical professor of physiological chemistry
(1955-1961), associate professor of physiological chemistry and nuclear medicine (1961-65) and professor of biological chemistry
(1965-87) in the UCLA School of Medicine. He pioneered the use of cultured (in vitro) mammalian heart cells as a model system
after demonstrating that they retain cardiac functions in the single, isolated cell. The collection consists of autobiographical
and biographical material, teaching material, correspondence, contracts and grants, data files, laboratory notebooks, publications,
manuscripts, awards, and a videotape.
Physical location: Stored off-site at SRLF. Advance notice is required for access to the collection. Please contact the UCLA Library, Department
of Special Collections Reference Desk for paging information.
Restrictions on Use and Reproduction
Property rights to the physical object belong to the UCLA Library, Department of Special Collections. Literary rights, including
copyright, are retained by the creators and their heirs. It is the responsibility of the researcher to determine who holds
the copyright and pursue the
copyright owner or his or her heir for permission to publish where The UC Regents do not hold the copyright.
Restrictions on Access
COLLECTION STORED OFF-SITE AT SRLF: Advance notice required for access.
Portions of this collection are restricted. Consult finding aid for further information.
Additional Physical Form Available
A copy of the original version of this online finding aid is available at the UCLA Department of Special Collections for in-house
consultation and may be obtained for a fee. Please contact:
- Public Services Division
- UCLA Library, Department of Special Collections
- Room A1713, Charles E. Young Research Library
- Box 951575
- Los Angeles, CA 90095-1575
- Telephone: 310/825-4988 (10:00 a.m. - 4:45 p.m., Pacific
- Email: firstname.lastname@example.org
Provenance/Source of Acquisition
Gift of Isaac Harary, 1996.
[Identification of item], Isaac Harary Papers (Collection 372). Department of Special Collections, Charles E. Young Research
Library, University of California, Los Angeles.
UCLA Catalog Record ID
Harary was born on March 15, 1923 in New York City, New York; BA, Brooklyn College, 1945; Ph.D. in biochemistry, New York
University, 1952; postdoctoral fellowship with the American Cancer Society (1952-55); assistant clinical professor of physiological
chemistry (1955-1961); associate professor of physiological chemistry and nuclear medicine (1961-65); and professor of biological
chemistry (1965-87), UCLA School of Medicine; pioneered the use of cultured (in vitro) mammalian heart cells as a model system,
demonstrating that they retain cardiac functions in the single, isolated cell; his research included investigations of internal
and external environmental conditions which predispose the heart cell to maintain its function, the control of myosin synthesis
by metabolic and hormonal factors, the fusion of cultured skeletal cells, and the rate of calcium and cyclic AMP in cellular
Isaac Harary, a developmental biochemist, was born March 15, 1923 in New York, New York. He received a B.A. degree from Brooklyn
College (1941-1945) and a doctorate in biochemistry from New York University (1948-1952), followed by a postdoctoral fellowship
with the American Cancer Society (1952-1955). Harary was appointed to the faculty at UCLA in 1955 and spent the remainder
of his career there, ascending through the ranks as Assistant Clinical Professor (Physiological Chemistry, 1955-1961), Associate
Professor (Physiological Chemistry and Nuclear Medicine, 1961-1963; Biophysics and Nuclear Medicine, and Biological Chem-istry,
1963-1965), and Professor (Biological Chemistry,
Harary studied the mechanisms involved in the control of metabolism in differentiated cells, in particular the specialized
function and structure of the mammalian heart. He pioneered the use of cultured (
in vitro) mammalian heart cells as a model system, demonstrating that they retain cardiac functions in the single, isolated cell.
His research in the Laboratory of Nuclear Med-icine and Radiation Biology at UCLA included investigations of internal and
external environ-mental conditions which
predispose the heart cell to maintain its function, the control of myosin synthesis by metabolic and hormonal factors, the
fusion of cultured skeletal cells, and the role of calcium and cyclic AMP in cellular synthesis.
Scope and Content
Collection consists of autobiographical and biographical material, teaching material, correspondence, contracts and grants,
data files, laboratory notebooks, publications, manuscripts, awards, and a videotape. Includes Harary's curriculum vitae,
Ph.D. thesis, a nearly complete set of offprints and reprints of publications, programs from professional societies, and a
videotape copy of Beating heart calls, a documentary on Harary's in vitro studies of single beating heart cells.
Expanded Scope and Content
The papers of Isaac Harary span the years 1950-1991; the bulk of the material covers the period he spent at UCLA, from 1955-1987.
Autobiographical and biographical material include curriculum vitae, biobibliographies, and a scrapbook of news and media
reports on Harary and his research. the only representative of his own schooling is a copy of Harary's Ph.D. thesis; likewise,
there is a small number of class notes and syllabi from courses taught at UCLA. Correspondence with colleagues and students
and extensive personnel files on laboratory staff, students, and postdoctoral candidates include letters, notes, and memoranda,
but no photographs. Funded and unfunded contract and grant files contain applications, site visit notes,
revisions, and referee reports. Data files include protocols, laboratory notebooks, and correspondence; these comprise by
volume the largest set of material in the collection. Much of the surviving data, including the work of Charles Swanson, are
associated with unpublished manuscripts. a nearly complete set of offprints and reprints of publications is complemented by
published and unpublished manuscripts, lectures, speeches, programs from professional societies and sabbatical trips abroad,
and two awards. a highlight of the collection is a video-tape copy of Beating Heart Calls, a documentary on Harary's
in vitro studies of single beating heart cells.
Organization and Arrangement
Arranged in the following series:
- Autobiographical material.
- Biographical material.
- Personnel and students.
- Contracts and grants.
- Data files.
- Published manuscripts.
- Unpublished manuscripts.
- Lectures, speeches, and conferences.
- Audiovisual material.
The following terms have been used to index the description of this collection in the library's online public access catalog.
University of California, Los Angeles--School of Medicine--Dept. of Physiological Chemistry--Faculty--Archival resources.
Biochemists--California--Los Angeles--Archival resources.
Manuscripts for publication.