Leslie Orgel Papers

Mandeville Special Collections Library
Mandeville Special Collections Library
The UCSD Libraries
9500 Gilman Drive
University of California, San Diego
La Jolla, California 92093-0175
Phone: (858) 534-2533
Fax: (858) 534-5950
URL: http://orpheus.ucsd.edu/speccoll/
Copyright 2005
The Regents of the University of California. All rights reserved.


Descriptive Summary

Creator: Orgel, Leslie E.
Title: Leslie Orgel Papers,
Date (inclusive): 1960 - 1991
Extent: 16.40 linear feet (39 archives boxes and 1 oversize file folder)
Abstract: Papers of Leslie Orgel, chemist, molecular biologist and Senior Fellow and Research Professor at the Salk Institute for Biological Studies, where he directs the Chemical Evolution Laboratory. Orgel's research interests include nucleic acid chemistry, molecular evolution, prebiotic chemistry, and problems related to the origin of life. The bulk of the papers dates from 1964 to 1991 and includes correspondence, journal articles, conference and meeting material, contracts and grants, subject files, Salk Institute administrative files, and referee reports. The papers are arranged in eight series: 1) BIOGRAPHICAL MATERIAL, 2) CORRESPONDENCE, 3) WRITINGS, 4) CONTRACTS, GRANTS AND PROPOSALS, 5) CONFERENCES AND MEETINGS, 6) SUBJECT FILES, 7) SALK INSTITUTE, and 8) REFEREE REPORTS.
Repository: University of California, San Diego. Geisel Library. Mandeville Special Collections Library.
La Jolla, California 92093-0175
Collection number: MSS 0176
Language of Material: Collection materials in English

Access

Referee reports in boxes 37, 38, and 39 are restricted until the death of Leslie Orgel.

Acquisition Information

Not Available

Preferred Citation

Leslie Orgel Papers, MSS 0176. Mandeville Special Collections Library, UCSD.

Publication Rights

Publication rights are held by the creator of the collection.

Biography

Leslie Eleazer Orgel was born in London, England, on January 12, 1927. He received his B.A. in chemistry with first class honors from Oxford university in 1949. In 1950 he was elected a Fellow of Magdalen College and in 1951 was awarded his Ph.D in chemistry at Oxford.
Orgel started his career as a theoretical inorganic chemist and continued his studies in this field at Oxford, the California Institute of Technology and the University of Chicago. In 1955 he joined the chemistry department at Cambridge university.
There he did work in transition metal chemistry, published articles and wrote a textbook entitled TRANSITION METAL CHEMISTRY: LIGAND FIELD THEORY (1960).
In 1964 Orgel was appointed Senior Fellow and Research Professor at the Salk Institute for Biological Studies, where he directs the Chemical Evolution Laboratory. He is also an adjunct professor in the Department of Chemistry and Biochemistry at the University of California, San Diego, and he is one of five principal investigators in the NASA-sponsored NSCORT program in exobiology. Orgel also participated in NASA's Viking Mars Lander Program as a member of the Molecular Analysis Team that designed the gas chromatography mass spectrometer instrument.
Orgel's work in the Chemical Evolution Laboratory is in nucleotide chemistry and is mainly concerned with non-enzymatic polymerization reactions that depend on the formation of double-helical complexes between a preformed polynucleotide template and one or more complementary mononucleotide or polynucleotide substrates. In the context of chemical evolution, selected templates are employed to facilitate synthesis of complementary RNA sequences. In other work, oligonucleotide sequences are used to direct reactive molecules (warheads) to a complementary target DNA, so as to cleave a crosslink to the target at a predetermined position. Methods for crosslinking transcription factors irreversibly to their DNA recognition sequences are also being developed. His NASA-sponsored research focuses on the catalysis of nucleic acid replication by mineral surfaces.
Orgel wrote THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION (1970)
and co-authored, with Stanley Miller, THE ORIGINS OF LIFE ON THE EARTH (1974). He has published over three hundred articles in his research areas.
Orgel's contributions have been recognized throughout his career. In Britain he was awarded the Harrison Prize in 1957 for his work in inorganic chemistry and elected a Fellow of the Royal Society in 1962. In the United States he received a Guggenheim Fellowship in 1971, the Evans Award from Ohio State University in 1975, and the H.C. Urey Medal from the International Society for the Study of the Origin of Life. He was elected a member of the National Academy of Sciences in 1990.

Scope and Content of Collection

The Leslie Orgel Papers document research in nucleic acid chemistry and molecular evolution conducted between 1964 and 1991 at the Chemical Evolution Laboratory of the Salk Institute for Biological Studies. The papers contain correspondence, manuscripts of Orgel's books and journal articles, grants and proposals, conference and meeting material, subject files, Salk Institute files, and referee reports written by Orgel.
The papers are arranged in eight series: 1) BIOGRAPHICAL MATERIAL, 2) CORRESPONDENCE, 3) WRITINGS, 4) CONTRACTS, GRANTS AND PROPOSALS, 5) CONFERENCES AND MEETINGS, 6) SUBJECT FILES, 7) SALK INSTITUTE, and 8) REFEREE REPORTS.
SERIES 1: BIOGRAPHICAL MATERIAL
Arranged alphabetically, the BIOGRAPHICAL MATERIAL series contains Orgel's annotated wall calendars, newspaper clippings and his application for naturalization as a U.S. citizen.
SERIES 2: CORRESPONDENCE
The CORRESPONDENCE series is arranged in four subseries: A) Outgoing Chronological Files, B) General, C) Scientific, and D) Personal.
A) The Outgoing Chronological Files subseries contains copies of outgoing letters (1964-1991).
B) The General subseries contains correspondence associated with routine laboratory business: letters of inquiry regarding possible employment, correspondence with suppliers, requests for visits, and cordial correspondence. In most cases, the incoming letters are accompanied by outgoing replies. The correspondence is arranged chronologically.
C) The Scientific subseries includes correspondence with colleagues and other scientists regarding scientific and technical issues. The materials are arranged alphabetically by author. Prominent correspondents include F.H.C. Crick, Robin Holliday, Jean-Michel Labouygues, Stanley Miller, Carl Sagan, S.A. Seleznev, and Eugene Wigner.
D) The Personal subseries includes letters to and from friends and correspondence related to personal interests, travel plans and projects.
SERIES 3: WRITINGS
The WRITINGS series is organized in two subseries: A) Published, and B) Unpublished.
A) The Numbered Publications subseries, arranged numerically, largely contains research articles and begins with Orgel's numbered chronological list of publications. The folders contain drafts, final versions, correspondence, redacted referee reports, and reprints. The subseries contains 259 of the 302 listed titles, including the draft and correspondence for his textbook entitled TRANSITION METAL CHEMISTRY: LIGAND FIELD THEORY (1960), the only representative from his work while in England. Also included are materials for his other two books, THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION (1973) and, THE ORIGINS OF LIFE ON THE EARTH (1974) with Stanley L. Miller. Of particular interest are Orgel's files for two collaborative articles with Francis Crick, "Directed Panspermia" (#137) and "Selfish DNA: The Ultimate Parasite" (#186), which contain abundant correspondence.
B) The Unpublished subseries contains titles that do not appear on Orgel's publications list.
SERIES 4: CONTRACTS, GRANTS AND PROPOSALS
The series is arranged by sponsoring agency in four subseries: A) National Aeronautics and Space Administration (NASA), B) National Institutes of Health (NIH), C) National Science Foundation (NSF), and D) U.S. Army. Within each subseries the materials are arranged chronologically and, in most cases, include a copy of the proposal or contract, correspondence and summary budget information. The NASA series reflects the development of Orgel's long-term research grant entitled "Models for the Generation of Prebiotic Condensing Agents" and his participation in planning for the 1975 Viking Mars Lander mission.
SERIES 5: CONFERENCES AND MEETINGS
The CONFERENCES AND MEETINGS series in arranged chronologically and begins with several summary lists of meetings that Orgel attended. The conference materials include programs, speaker lists and correspondence.
SERIES 6: SUBJECT FILES
The SUBJECT FILES series begins with material associated with Orgel's research interest on the topic of aging, including drafts of a planned, but never published, book written in collaboration with British colleague Robin Holliday, and correspondence files arranged chronologically. Also included are grant files and material reflecting the Salk Institute's research and presentations on aging.
The remaining subject files contain material about several colleagues and correspondence related to a planned book about the history of the groundbreaking group of RNA researchers who belonged to the RNATIECLUB, a mid-1950's society with twenty members dedicated to unraveling the genetic code. Included are photocopies of correspondence (1953-1962) from George Gamow to James Watson and Alexander Rich.
SERIES 7: SALK INSTITUTE
The SALK INSTITUTE series contains files that document Orgel's association and interaction with the Salk Institute and is arranged in six subseries: A) Chemical Evolution Laboratory, B) Faculty, C) Fellows, D) General, E) Salk Memoranda, and F) Salk Institute Biotechnology/Industrial Associates (SIBIA). Included are numerous reports; memoranda with Jacob Bronowski, Frederic De Hoffman and Edwin Lennox; and, files related to the commercial development of biotechnology research by Orgel and his associates.
SERIES 8: REFEREE REPORTS
The REFEREE REPORTS series contains referee reports by Orgel arranged alphabetically by title of journal or name of agency. Orgel was a referee for BIOCHIMICA ET BIOPHYSICA ACTA, BIOINORGANIC CHEMISTRY, the JOURNAL OF MOLECULAR EVOLUTION, the JOURNAL OF THEORETICAL BIOLOGY, and the National Science Foundation.
Referee reports are restricted until the death of Leslie Orgel.

Indexing Terms

The following terms have been used to index the description of this collection in the library's online public access catalog.

Subjects

Orgel, Leslie E. -- Archives
Salk Institute for Biological Studies. -- Chemical Evolution Laboratory
Salk Institute for Biological Studies -- Faculty
Journal of Theoretical Biology Journal of Molecular Evolution
Chemistry, Inorganic
Chemists -- Biography
Ligand field theory
Valence (Theoretical chemistry)
Life -- Origin
Molecular evolution
Aging

Contributors

Orgel, Leslie E. -- Origins of life
Orgel, Leslie E. -- Introduction to transition-metal chemistry
Gamow, George, 1904-1968, -- correspondent
Arrhenius, Gustaf, -- correspondent
Kornberg, Arthur, 1918- -- correspondent
Crick, Francis, 1916- -- correspondent
Holliday, R. -- (Robin), 1932- -- correspondent
Labouygues, Jean-Michel, -- correspondent
Miller, Stanley L., 1930- -- correspondent
Sagan, Carl, 1934- -- correspondent
Selezne, S. A., -- correspondent
Wigner, Eugene Paul, 1902- -- correspondent


Collection Contents

 

BIOGRAPHICAL MATERIAL

box 1, folder 1, oversize FB20801

Calendars 1982 - 1991

box 1, folder 2

Newspaper clippings

box 1, folder 3

United States Department of Justice. Immigration and Naturalization Service. Application for Naturalization 1989

 

CORRESPONDENCE

 

Outgoing Chronological Files

box 1, folder 4

1964 January, September-December

box 1, folder 5

1965 January-April

box 1, folder 6

1965 May-August

box 1, folder 7

1965 September-December

box 2, folder 1

1966 January-April

box 2, folder 2

1966 May-July

box 2, folder 3

1966 August-December

box 2, folder 4

1967 January-May

box 2, folder 5

1967 June-December

box 2, folder 6

1968

box 2, folder 7

1969

box 2, folder 8

1970 January-September

box 2, folder 9

1972 February-September

box 2, folder 10

1973 July-October

box 2, folder 11

1975 September-December

box 2, folder 12

1976 March-December

box 3, folder 1

1977

box 3, folder 2

1978

box 3, folder 3

1979 January-April

box 3, folder 4

1979 May-December

box 3, folder 5

1980 January-July

box 3, folder 6

1980 August-December

box 3, folder 7

1981 January-August

box 3, folder 8

1981 September-December

box 3, folder 9

1982 January-June

box 3, folder 10

1982 July-December

box 3, folder 11

1983 January-May

box 4, folder 1

1983 June-December

box 4, folder 2

1984 January-June

box 4, folder 3

1984 July-December

box 4, folder 4

1984 January-February

box 4, folder 5

1985 March-May

box 4, folder 6

1985 June-December

box 4, folder 7

1986 January-September

box 4, folder 8

1986 October-December

box 4, folder 9

1987 January-March

box 4, folder 10

1987 April-July

box 5, folder 1

1987 August-September

box 5, folder 2

1988 January-April

box 5, folder 3

1988 May-August

box 5, folder 4

1988 September-December

box 5, folder 5

1989 January-March

box 5, folder 6

1989 April-July

box 5, folder 7

1989 August-December

box 5, folder 8

1991 January-July

box 6, folder 1

1991 August-December

 

General

box 6, folder 2

1964-1966

box 6, folder 3

1967-1969

box 6, folder 4

1970-1974

box 6, folder 5

1975-1977

box 6, folder 6

1978-1985

box 6, folder 7

1986-1989

 

Scientific

box 7, folder 1

A - miscellaneous

box 7, folder 2

Altman, Sidney 1984

box 7, folder 3

American Institute of Biological Sciences 1973 - 1979

box 7, folder 4

AMERICAN JOURNAL OF HUMAN GENETICS 1978 - 1980

Note

David E. Comings, editor.
box 7, folder 5

AMERICAN SCIENTIST 1973 - 1979

box 7, folder 6

Arrhenius, Gustaf 1974 - 1984

box 7, folder 7

ASSOCIATED SCIENTIFIC PUBLISHERS 1973

Note

F. Suater, Dept. managing director.
box 7, folder 8

Avracmides, George 1982

box 7, folder 9

B - miscellaneous (Ba - Ber)

box 7, folder 10

B - miscellaneous (Ber - By)

box 7, folder 11

Balasubramanian, R. 1983

box 7, folder 12

Baltscheffsky, Herrick 1977 - 1978

box 7, folder 13

Ben-Nun, Akiva 1971 - 1976

box 7, folder 14

Botkin, Daniel B. 1982 - 1983

box 7, folder 15

Brack, Andre 1977 - 1982

box 7, folder 16

British Broadcasting Corporation 1976 - 1980

box 7, folder 17

C - miscellaneous

box 7, folder 18

Carmell, L. 1974

box 7, folder 19

Comfort, Alex 1973 - 1978

box 7, folder 20

Crick, F.H.C. 1965 - 1974

box 7, folder 21

D - miscellaneous

box 7, folder 22

Danielli, James F. 1974 - 1980

box 7, folder 23

Dickerson, Richard E. 1979 - 1981

box 7, folder 24

Dyson, Freeman 1981

box 8, folder 1

E - miscellaneous

box 8, folder 2

Eirich, F.R. 1984

box 8, folder 3

Encyclopedia of Ignorance (Miranda Weston-Smith) 1974 - 1979

box 8, folder 4

Eschenmoser, A. 1966

box 8, folder 5

F - Miscellaneous

box 8, folder 6

Ferris, James P. 1969 - 1983

box 8, folder 7

G - miscellaneous

box 8, folder 8

Galas, David J. 1973 - 1980

box 8, folder 9

Gallant, Jonathon A. 1977

box 8, folder 10

Gould, Stephen Jay 1981

box 8, folder 11

Granada Television Limited (Jack Smith, Executive Producer) 1979 - 1980

box 8, folder 12

H - miscellaneous

box 8, folder 13

Hendry, Lawrence B. 1981 - 1983

box 8, folder 14

Holliday, Robin 1964 - 1978

Note

See also Series 6: Aging.
box 8, folder 15

Horowitz, N.H. 1970 - 1984

box 8, folder 16

I - miscellaneous

box 8, folder 17

Idiot papers and comments 1964 - 1979

box 8, folder 18

International Society for the Study of the Origin of Life 1989

box 8, folder 19

J - miscallaneous

box 8, folder 20

K - miscellaneous

box 8, folder 21

Kendrew, John C. 1967 - 1975

box 8, folder 22

Khorana, Gobind H. 1969 - 1978

box 9, folder 1

Kornberg, Arthur 1968 - 1981

box 9, folder 2

L - miscellaneous

box 9, folder 3

Labouygues, Jean-Michel 1974 - 1982

box 9, folder 4

Lagerkvist, Ulf 1977 - 1979

box 9, folder 5

Lasser, David 1981 - 1982

Note

Includes interview with Orgel.
box 9, folder 6

Leonard, Nelson 1988 - 1989

box 9, folder 7

M - miscellaneous

box 9, folder 8

Mandell, Arnold J. 1981 - 1982

box 9, folder 9

Michelson, A.M. 1967 - 1968

box 9, folder 10

Miles, Todd 1971 - 1983

box 9, folder 11

Miller, Stanley L. 1975 - 1983

box 9, folder 12

Monod, Jacques 1963 - 1973

box 9, folder 13

N - miscellaneous

box 9, folder 14

National Academy of Sciences 1990

box 9, folder 15

NATURE (Elizabeth Hughes, publisher) 1981

box 9, folder 16

Neurologische Klinik der Universitat 1974 - 1975

box 9, folder 17

Ninio, Jacques 1974 - 1981

box 9, folder 18

O - miscellaneous

box 9, folder 19

Oro, John 1965 - 1983

box 9, folder 20

P - miscellaneous

box 9, folder 21

Paecht-Horowitz, Mella 1972

box 9, folder 22

Peters, David 1981

box 9, folder 23

Phillips, William 1965 - 1966

box 9, folder 24

Pitha, Josef 1969 - 1974

box 9, folder 25

Ponnamperuma, Cyril 1965 - 1970

box 9, folder 26

R - miscellaneous

box 9, folder 27

Rabinowitz, Joseph M. 1969 - 1970

box 9, folder 28

Reese, Colin B. 1981 - 1984

box 10, folder 1

Robins, Roland K. 1968 - 1969

box 10, folder 2

Royal Society 1970 - 1985

box 10, folder 3

S - miscellaneous (Sa - Sh)

box 10, folder 4

S - miscellaneous (Si - Su)

box 10, folder 5

Sagan, Carl 1973 - 1982

box 10, folder 6

Schwartz, Alan W. 1972 - 1981

box 10, folder 7

Seleznev, S. A. 1974 - 1975

box 10, folder 8

Sobell, Henry M. 1965 - 1982

box 10, folder 9

Stein, Gabriel 1965 - 1968

box 10, folder 10

Strehler, Bernard L. 1974 - 1981

box 10, folder 11

T - miscellaneous

box 10, folder 12

Thaxton, Charles B. 1981 - 1983

box 10, folder 13

Todd, John H. 1969

box 10, folder 14

Townes, Charles 1970 - 1972

box 10, folder 15

TRENDS IN BIOCHEMICAL SCIENCES 1975 - 1980

Note

Joan Morgan, staff editor.
box 10, folder 16

Ts'o, Paul O. P. 1968 - 1976

box 10, folder 17

U - miscellaneous

box 10, folder 18

Usher, David A. 1975 - 1983

box 10, folder 19

V - miscellaneous

box 10, folder 20

Verheyden, Julien P. H. 1983

box 10, folder 21

W - miscellaneous

box 10, folder 22

Watson, J. D. 1980

box 10, folder 23

Wells, Robert D. 1982 - 1984

box 10, folder 24

Westheimer, Frank H. 1970 - 1984

box 11, folder 1

Wigner, Eugene P. 1963 - 1970

box 11, folder 2

Worth Publishers, Inc. 1973

box 11, folder 3

Y - miscellaneous

box 11, folder 4

Z - miscellaneous

box 11, folder 5

Z - Miscellaneous

box 11, folder 6

Zubay, Geoffrey 1979

box 11, folder 7

Unidentified correspondents

 

Personal

box 11, folder 8

1971

box 11, folder 9

1972-1975

box 11, folder 10

1976-1981

box 11, folder 11

1982-1987

box 11, folder 12

1988-1992

 

Name, A-Z

 

WRITINGS

 

Published

box 11, folder 13

List of publications 1951 - 1997

box 11, folder 14

61 - INTRODUCTION TO TRANSITION METAL CHEMISTRY: LIGAND FIELD THEORY 1960

box 11, folder 15

87 - Induction of Mutations in Bacteriophage T4 with Divalent Manganese 1965

box 11, folder 16

89 - Reactions of Bromomalononitrile with Bases 1965

box 11, folder 17

90 - Formation of Condensed Phosphate in Aqueous Solution 1965

box 12, folder 1

91 - Aminomalononitrile and 4-Amino-5- Cyanomidazole in Hydrogen Cyanide Polymerization and Adenine Synthesis 1965

box 12, folder 2

93 - Photochemical Synthesis of Condensed Phosphates 1965

box 12, folder 3

94 - An Unusual Photochemical Rearrangement in the Synthesis of Adenine from Hydrogen Cyanide 1966

box 12, folder 4

95 - Conditions for Purine Synthesis: Did Prebiotic Synthesis Occur at Low Temperatures? 1966

box 12, folder 5

96 - Studies in Prebiotic Synthesis I. Aminomalononitrile and 4-Amino-5-Cyanomiclazole 1966

box 12, folder 6

97 - Cyanoacetylene in Prebiotic Synthesis 1966

box 12, folder 7

101 - Nucleoside Synthesis Under Potentially Prebiotic Conditions 1967

box 12, folder 8

103 - Studies in Prebiotic Synthesis. II. Synthesis of Purine Precursors and Amino Acids from Aqueous... 1967

box 12, folder 9

104 - The Non-Enzymatic Synthesis of Deoxyadenylate Oligonucleotides on a Polyuridylate Template 1968

box 12, folder 10

105 - Studies in Prebiotic Synthesis. III. Synthesis of Pyrimidines from Cyanoacitylene and Cyanate 1968

box 12, folder 11

106 - Specificity of Oligonucleotide Synthesis Directed by Polyuridylic Acid 1968

box 12, folder 12

107 - Prebiotic Synthesis: Phosporylation in Aqueous Solution 1968

box 12, folder 13

108 - Template-Directed Synthesis with Adenosine-5'-Phosphorimidazolide 1968

box 12, folder 14

109 - Non-Enzymic Synthesis of Deoxyadenulate Oligonucleotides on a Polyuridylate Template 1968

box 12, folder 15

110 - Studies in Prebiotic. IV. The Conversion of 4-Aminoinidazole-5-Carbonitrile Derivatives to Purines 1968

box 12, folder 16

111 - Partial Resolution of DL-Adenosine by Template Synthesis 1968

box 12, folder 17

112 - Evolution of the Genetic Apparatus 1968

box 12, folder 18

114 - Non-Enzymic Oligonucleotide Synthesis on a Polytidylate Template 1969

box 12, folder 19

115 - Phosphorylation of D-Ribose in Aqueous Solution 1969

box 12, folder 20

116 - Specificity of Template-Directed Synthesis with Adenosine Nucleotides 1970

box 12, folder 21

117 - Studies in Prebiotic Synthesis. V. Synthesis and Photoanomerization of Pyrimidine Nucleosides 1970

box 12, folder 22

119 - In Vitro Selection of QB Ribonucleic Acid Variants Resistant to Ethidium Bromide 1970

box 12, folder 23

120 - Prebiotic Synthesis of Propiolaldehyde and Nicotinamide 1970

box 12, folder 24

121 - The Maintenance of the Accuracy of Protein Synthesis and Its Relevance to Ageing: A Correction 1970

box 12, folder 25

122 - Template Catalysis of Acetyl Transfer Reactions 1971

box 12, folder 26

123 - Urea-Inorganic Phosphate Mixtures as Prebiotic Phosphorylating Agents 1971

box 12, folder 27

124 - The Mechanism of the Trimetaphosphate-Induced Peptide Synthesis 1971

box 13, folder 1

125 - Catalysts for the Polymerization of Adenosine Cyclic 2',3'-Phosphate on a Poly(U) Template 1971

box 13, folder 2

128 - Prebiotic Phosphorylation of Thymidine at 65 Degrees Centigrade in Simulated Desert Conditions 1972

box 13, folder 3

129 - Studies in Prebiotic Synthesis. VI. Synthesis of Nucleosides 1972

box 13, folder 4

130 - Polyphosphate and Trimetaphosphate Formation Under Potentially Prebiotic Conditions 1972

box 13, folder 5

131 - Studies in Prebiotic Synthesis. VII. Solid-State Synthesis of Purine Nucleosides 1972

box 13, folder 6

132 - A Possible Step in the Origin of the Genetic Code 1972

box 13, folder 7

133 - THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION 1973

box 13, folder 8

133 - THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION 1973

Note

Figures and photographs (part 1).
box 13, folder 9

133 - THE ORIGINS OF LIFE: MOLECULES AND NATURAL SELECTION 1973

Note

Figures and photographs (part 2).
box 13, folder 10

134 - Struvite and Prebiotic Phosporylation 1973

box 13, folder 11

135 - An RNA that Multiplies Indefinitely with DNA-Dependent RNA Polymerase: Selection from a Random Copolymer 1973

box 13, folder 12

136 - Further Studies of Urea-Catalyzed Phosphorylation Reactions 1973

box 13, folder 13

137 - Directed Panspermia 1973

box 13, folder 14

137 - Directed Panspermia 1973

Note

Correspondence.
box 13, folder 15

139 - Ageing of Clones of Mammalian Cells 1973

box 14, folder 1

140 - Prebiotic Activation Processes 1973

box 14, folder 2

141 - The Effect of Mg2+ and Ca2+ on Urea-Catalyzed Phosphorylation Reactions 1973

box 14, folder 3

142 - Catalysts for the Self-Polymerization of Adenosine Cyclic 2',3'-Phosphate 1973

box 14, folder 4

143 - Analysis of High Molecular Weight Material from the Polymerization of Adenosine Cyclic 2',3'-Phosphate 1974

box 14, folder 5

144 - THE ORIGINS OF LIFE ON THE EARTH 1974

box 14, folder 6

145 - On the Possible Role of Crystals in the Origins of Life. VII. The Adsorption and Polymerization... 1974

box 14, folder 7

146 - Sedimentary Minerals Under Reducing Conditions 1974

box 14, folder 8

147 - Prebiotic Chemistry and Nucleic Acid Replication 1974

box 14, folder 9

149 - Poly(U)-Directed Transamidation Between Adenosine 5'-Phophorimidazolide and ... 1974

box 14, folder 10

150 - Oligonucleotide Synthesis Catalyzed by the Zn2+ Ion 1975

box 14, folder 11

151 - Prebiotic Peptide-Formation in the Solid State 1975

box 14, folder 12

152 - Triple Helices Formed by Polyuridylic Acid With Some Adenosine Derivatives 1975

box 14, folder 13

153 - Prebiotic Peptide-Formation in the Solid State. II. Reaction of Glycine with Adenosine... 1975

box 14, folder 14

154 - Prebiotic Peptide-Formation in the Solid State. III. Condensation Reactions of Glycine in Solid... 1975

box 14, folder 15

155 - (Beta) Structure of Alternating Polypeptides and Their Possible Prebiotic Significance 1975

box 14, folder 16

156 - Prebiotic Polynucleotides and Polypeptides 1975

box 14, folder 17

158 - N,N-Carbonyldiimidazole-Induced Peptide Formation in Aqueous Solution 1976

box 14, folder 18

159 - Polymerization of Nucleotide Analogues I: Reaction of Nucleoside 5'-Phosphorimidazolides... 1976

box 14, folder 19

160 - Tenokate-Directed Synthesis of High Molecular Weight Polynucleotide Analogues 1976

box 14, folder 20

161 - Triple Helices Formed by Polyuridylic Acid with Some Amino Deoxyadenosine Derivatives 1976

box 14, folder 21

162 - Search for Organic and Volatile Inorganic Compounds in Two Surface Samples from the Chryse Planitia... 1976

box 14, folder 22

163 - N,N-Carbonyldiimidazole-Induced Deketopiperazine Formation in Aqueous Solution in the Presence... 1976

box 14, folder 23

164 - Some 5'-Azido and 5'-Amino-2'-Deoxyribonucleotides, Their 3'-Phosphates and Their... 1976

box 14, folder 24

165 - Reactions of Polyfunctional Amino Acids with N',N'-Carbonyldiimidazole in Aqueous Solution... 1977

box 15, folder 1

166 - (Beta)-Turns and the Evolution of Protein Synthesis 1977

box 15, folder 2

167 - Reactions of Adenosine 5'-Phosphorimidazolide with Adenosine Analogs on a Polyuridylic Template 1977

box 15, folder 3

168 - Template-Directed Reactions of Aminonucleosides 1977

box 15, folder 4

169 - Gene Duplication and the Origin of Proteins with Novel Functions 1977

box 15, folder 5

170 - The Search for Organic Substances and Inorganic Volatile Compounds in the Surface of Mars 1977

box 15, folder 6

171 - Template-Directed Polynucleotide Condensation as a Model for RNA Replication 1978

box 15, folder 7

172 - Preferential Formation of (2'-5')-Linked Internucleotide Bonds in Non-Enzymatic Reactions 1978

box 15, folder 8

173 - Formation of P1,P2-Dinucleoside 5'-Pyrophosphates Under Potentially Prebiological Conditions 1978

box 15, folder 9

174 - Amino Acid Activation with Adenosine 5'-Phosphorimidazole 1978

box 15, folder 10

175 - Phosporylation of Nucleosides in Aqueous Solution Using Trimetaphosphate: Formation of Nucleoside... 1978

box 15, folder 11

176 - Formation of the Imidazolides of Dinucleotides Under Potentially Prebiotic Conditions 1978

box 15, folder 12

177 - The Formation of Peptides from the 2'(3')-Glycyl Ester of a Nucleotide 1978

box 15, folder 13

178 - Heteropolynucleotides as Templates for Non-Enzymatic Polymerizations 1978

Note

A prior version titled "Template-Directed Condensation in Oligoadenylic Acids" is located in Series 3B.
box 15, folder 14

179 - Studies of Oligoadenylate Formation on a Poly(U) Template 1979

box 15, folder 15

180 - The Catalysis of Nucleotide Polymerization by Compounds of Divalent Lead 1979

box 15, folder 16

181 - Selection In Vitro 1979

box 15, folder 17

182 - The Formation of Dipeptides from Amino Acids and the 2'(3')-Glycyl Ester of an Adenylate 1979

box 15, folder 18

183 - The Formation of Peptides from Glycine Thioesters 1979

box 15, folder 19

184 - Template-Directed Synthesis of Oligoadenylates Catalyzed by Pb2+ Ions 1979

box 15, folder 20

185 - Self-Condensation of Activated Dinucleotides on Polynucleotide Templates with Alternating Sequences 1979

box 16, folder 1

186 - Selfish DNA: The Ultimate Parasite 1980

box 16, folder 2

186 - Selfish DNA 1980

Note

Correspondence: February - May.
box 16, folder 3

186 - Selfish DNA 1980

Note

Correspondence: June - October.
box 16, folder 4

188 - Efficient Metal-Ion Catalyzed Template-Directed Oligonucleotide Synthesis 1980

box 16, folder 5

189 - Template-Directed Synthesis and Selective Adsorption of Oligoadenylates on Hydroxyapatile 1980

box 16, folder 6

190 - Poly(U)-Directed Peptide Bond Formation from the 2'(3')-Glycyl Ester of Adenosine Derivatives 1980

box 16, folder 7

191 - Efficient Catalysis of Polycytidylic Acid-Directed Oligoguanylate Formation by Zn2+ 1980

box 16, folder 8

192 - Catalysis of Accurate Poly(C)-Directed Synthesis of 3'-5'-Linked Oligoguanylates by Zn2+ 1980

box 16, folder 9

193 - Template-Directed Synthesis of Oligoguanylic Acids - Metal Ion Catalysis 1981

box 16, folder 10

194 - Template-Directed Synthesis of Oligoguanylates in the Presence of Metal Ions 1980

box 16, folder 11

196 - The Effect of Poly(C) on the Formation of Peptide Bonds from the 2'(3')-Gycyl Ester of a Guanosine... 1981

box 16, folder 12

197 - Synthesis of Oligoguanylates on Oligocytidylate Templates 1981

box 16, folder 13

198 - Condensation of Activated Diguanylates on a Poly(C) Template 1981

box 16, folder 14

199 - Substituent Control of the Poly(C)-Directed Oligomerization of Guanosine 5'... 1981

box 16, folder 15

200 - Template-Directed Reactions of 2-Aminoadenylic Acid Derivatives 1982

box 16, folder 16

201 - Oligomerization of (Guanosine 5'-Phosphor)-2-Methylimidazolide on Poly(C): An RNA Polymerase... 1982

box 16, folder 17

202 - Darwinism At the Very Beginning of Life 1982

box 16, folder 18

203 - A Non-Enzymatic RNA Polymerase Model 1983

box 16, folder 19

204 - The Origin of Life and the Evolution of Macromolecules 1983

box 17, folder 1

205 - Derivation of Unprotected Polynucleotides 1983

box 17, folder 2

206 - Temperature-Dependence of the Template-Directed Synthesis of Oligoguanylates 1984

box 17, folder 3

207 - Preparation of Ligation Intermediates and Related Polynucleotide Pyrophosphates 1984

box 17, folder 4

208 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,U) Templates 1984

box 17, folder 5

209 - Chiral Selection in Poly(C)-Directed Synthesis of Oligo(G) 1984

box 17, folder 6

210 - Template-Directed Synthesis on the Pentanucleotide CpCpGpCpC 1984

box 17, folder 7

211 - Template-Directed Synthesis with 2-Aminoadenosine 1984

box 17, folder 8

212 - Non-Enzymatic Sequence-Specific Cleavage of Single-Stranded DNA 1985

box 17, folder 9

213 - Oligomerization of Activated Derivatives of 3'-Amino-3'-Deoxyguanosine on Poly(C) and Poly(dC)... 1985

box 17, folder 10

214 - Template-Directed Synthesis of Oligodeoxycytidylate and Polydeoxycytidylate Templates 1980

box 17, folder 11

215 - Template-Directed Synthesis of Novel, Nucleic Acid-Like Structures 1985

box 17, folder 12

217 - Template-Directed Polynucleotide Synthesis on Mineral Surfaces 1985

Note

Letter to the editor.
box 17, folder 13

218 - Detection of Specific DNA Sequences with Short Biotin-Labeled Probes 1985

box 18, folder 1

220 - Template-Directed Synthesis on the Oligonucleotide d(C7GC7) 1986

box 18, folder 2

221 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,G) Templates 1986

box 18, folder 3

222 - Template Properties of Some Oligodeoxynucleotides Containing Cytidine and Guanosine 1986

box 18, folder 4

223 - Template-Directed Oligonucleotide Ligation on Hydroxylapatite 1986

box 18, folder 5

224 - Synthesis of an Amplifiable Reporter RNA for Bioassays 1986

box 18, folder 6

225 - Molecular Replication and the Origins of Life 1986

box 18, folder 7

226 - Template-Directed Synthesis on Short Oligoribocytidylates 1986

box 18, folder 8

227 - How Mistakes Are Made 1986

box 18, folder 9

228 - Did Template-Directed Nucleation Precede Molecular Replication? 1986

box 18, folder 10

229 - Mini-Review. RNA Catalysis and the Origins of Life, Part 1 1986

box 18, folder 11

229 - RNA Catalysis and the Origins of Life, Part 2 1986

box 18, folder 12

230 - Oligoaminonucleoside Phosphoramidates. Oligomerization of Dimers of 3'-Amino-3' 1987

box 18, folder 13

231 - Action of a Water-Soluble Carbodiimide on Adenosine-5'--Polyphosphates 1987

box 19, folder 1

232 - Autocatalytic Synthesis of a Tetranucleotide Analogue 1987

box 19, folder 2

233 - Oligomerization of 3'-Amino-3'-Deoxyguanosine-5'-Phosphorimidazolidate..

box 19, folder 3

234 - A Case for an Ancestral Genetic System Involving Simple Analogues of the Nucleotides 1987

box 19, folder 4

235 - Impressions: LII Cold Spring Harbor Symposium on Quantitative Biology, the Evolution of Catalytic... 1987

box 19, folder 5

236 - Non-Enzymatic Transcription of an Oligodeoxynucleotide 14 Residues Long 1987

box 19, folder 6

237 - Evolution of the Genetic Apparatus: A Review 1987

box 19, folder 7

238 - The Origin of Self-Replicating Molecules 1987

box 19, folder 8

239 - Template-Directed Oligomerization of 3-Isoadenosine 5'-Phosphate 1988

box 19, folder 9

240 - Ligation of Oligonucleotides to Nucleic Acids or Proteins Via Disulfide Bonds 1988

box 19, folder 10

241 - Non-Enzymatic Template-Directed Synthesis on RNA Random Copolymers: Poly(C,A) Templates 1988

box 19, folder 11

242 - Cyclization of Nucleotide Analogues as an Obstacle to Polymerization 1989

Note

Letter to the editor.
box 19, folder 12

243 - Some Acyclic Analogues of Nucleotides and Their Template-Directed Reactions 1989

box 19, folder 13

245 - Reaction on Alternating GC Oligonucleotide Templates 1989

box 19, folder 14

246 - Replacement of the 3'-CH Group by Nitrogen in the Carbolic Analogue of Thymidine 1989

box 19, folder 15

247 - Was RNA the First Genetic Polymer? 1989

box 20, folder 1

248 - Template Properties of Tetranucleoside Triphosporamidates Having Cytosine-Guanosine Residues 1989

box 20, folder 2

249 - Polymerization of a Momeric Guanosine Derivative in a Hydrogen-Bonded Aggregate 1989

box 20, folder 3

250 - The Origin of Polynucleotide-Directed Protein Synthesis 1989

box 20, folder 4

251 - Polymerization of the Cyclic Pyrophosphates on Nucleosides and Their Analogues 1990

box 20, folder 5

Between 251 and 252 - Nucleic Acids: Adding to the Genetic Alphabet 1990

box 20, folder 6

252 - A Simple Procedure for Cross-Linking Complementary Oligonucleotides 1990

box 20, folder 7

253 - Polymerization of Amino Acids Containing Nucleotide Bases 1990

box 20, folder 8

255 - Blunt-End and Single-Strand Ligations by Escherichia Coli Ligase: Influence on an In Vitro... 1990

box 20, folder 9

257 - Synthesis of 5'-Deoxy-5'-Nucleosideacetic Acid Derivatives 1990

box 20, folder 10

258 - Pyrophosphate-Formation As the Most Efficient Condensation Reaction of Activated Nucleotides 1991

box 20, folder 11

259 - Disulfide-Linked Oligonucleotide Phosphothioates: Novel Analogues of Nucleic Acids 1991

box 20, folder 12

260 - Acceleration of the Template-Directed Reactions of Nucleoside 5'-Phosphorimidazolides by Acylation 1991

box 20, folder 13

261 - The Cyclization of Arabinosyladenine-5'-Phosphorimidazolide 1991

box 20, folder 14

262 - Which 3-Ribofuranosyl-Substituted Purine 5'Phosphates Undergo Template-Directed Oligomerization? 1991

box 20, folder 15

263 - Template-Directed Extension of a Guanosine 5'Phosphate Covalently Attached to an Oligodeoxycytidylate... 1991

box 20, folder 16

264 - The Photooxidation of Oligodeoxynucleotides by UO2 2+ 1991

box 21, folder 1

265 - Efficient Sequence-Specific Method for Crosslinking Complementary Oligonucleotides Using Binuclear... 1991

 

Unpublished

box 21, folder 2

Existence of Self-Reproducing Units

box 21, folder 3

Oligomerization of Dimers of 3'-Amino-3'-Deoxynucleotides Having Complementary AC and GU Sequences

box 21, folder 4

Poly(dC) as a Template for Non-Enzymatic Oligo(G) Synthesis

box 21, folder 5

Polymerization of a Monomeric Guanosine Derivative in a Hydrogen Bonded Aggregate

box 21, folder 6

Template-Directed Condensation of Oligoadenylic Acids, Part 1

Note

The published version of this paper is located in Series 3A: 178 - Heteropolynucleotides as Templates for Non-Enzymatic Polymerizations.
box 21, folder 7

Template-Directed Condensation of Oligoadenylic Acids, Part 2

box 21, folder 8

Thermal Synthesis of Oligourdylates at Moderate Temperatures

 

CONTRACTS, GRANTS AND PROPOSALS

 

National Aeronautics and Space Administration

box 21, folder 10

1969: Photochemical Generation of Prebiotic Condensing Agents

box 21, folder 11

1970: Models for the Generation of Prebiotic Condensing Agents

box 21, folder 12

1970: Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular Analysis

box 21, folder 13

1971: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 1

1971: Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular Analysis

box 22, folder 2

1972-1980: Participation in the Science Planning for the Viking 1975 Missions in the Area of Molecular..

box 22, folder 3

1972: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 4

1973: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 5

1974: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 6

1975: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 7

1976: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 8

1977: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 9

1978: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 10

1982: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 11

1982: RNA Polymerase Models

box 22, folder 12

1983: Models for the Generation of Prebiotic Condensing Agents

box 22, folder 13

1984: Models for the Generation of Prebiotic Condensing Agents

box 23, folder 1

1985: Models for the Generation of Prebiotic Condensing Agents

box 23, folder 2

1985: Prebiotic Template-Directed Synthesis

box 23, folder 3

1986: Models for the Generation of Prebiotic Condensing Agents

box 23, folder 4

1987: Models for the Generation of Prebiotic Condensing Agents

box 23, folder 5

1988: Models for the Generation of Prebiotic Condensing Agents

 

National Institutes of Health

box 23, folder 6

1965-1966: Evolution of Genetic Specificity

box 23, folder 7

1967-1968: Evolution of Genetic Specificity

box 23, folder 8

1971-1974: Nucleic Acid Analogs - Synthesis and Chemotherapy

box 24, folder 1

1975: Evolution of Genetic Specificity

box 24, folder 2

1976-1977: Evolution of Genetic Specificity

box 24, folder 3

1982-1984: Evolution of Genetic Specificity

box 24, folder 4

1985-1987: Evolution of Genetic Specificity

 

National Science Foundation

box 24, folder 5

1964-1965: Study of Biochemical Evolution

box 24, folder 6

1966-1969: Study of Biochemical Evolution

box 24, folder 7

1973-1978: Prebiotic Activation of Amino Acids and Nucleotide Bases

box 25, folder 1

1978-1979: Prebiotic Formation of Peptide Bonds

box 25, folder 2

1981-1983: A Non-Classical System of Template-Directed Synthesis

box 25, folder 3

1982-1984: Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides

box 25, folder 4

1985-1986: Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides

box 25, folder 5

1987-1989: Template-Directed Synthesis with 3'-Amino 3'-Deoxynucleotides

 

United States Army

box 25, folder 6

1985-1986: Sequence-Specific Inactivation of m-RNA

 

CONFERENCES AND MEETINGS

box 25, folder 7

Lists of meetings attended: 1975-1977, 1981-1985

box 25, folder 8

1971 September 5-11: First Soviet American Conference on Communication with Extraterrestrial Intelligence..

Note

1967 October 20: A series of "Telesnaps" photographs from a British Broadcasting Corporation program, numbered.
box 25, folder 9

1973 May 28: Quatrieme Conference Internationale de la Physique Theorique a la Biologie

box 25, folder 10

1975 February 27-28: Some Aspects of Pre-Biotic Chemistry - Some Theories of Ageing (and the Evidence)

box 25, folder 11

1975 March 2-7: Symposium on Nucleic Acid Replication

box 25, folder 12

1975 March 23-25: Fourth Annual Workshop on the Biology of Aging - Perspectives in Theories of Biological..

box 25, folder 13

1975 May 23: Polymerization and Polycondensation on Clays - Their Role in Abiotic Synthesis and the Origin..

box 26, folder 1

1975 May 26-28: European Molecular Biology Organization. Workshop, Part 1

box 26, folder 2

1975 May 26-28: European Molecular Biology Organization. Workshop, Part 2

Note

Contains letters by Carl Sagan (1/17/75) and Severo Ochoa (11/21/74).
box 26, folder 3

1975 August 7-11: Viking Science Symposium on Earth and Mars - The Role of Life

box 26, folder 4

1975 August 13: Prebiotic Synthesis of Nucleotides and Polynucleotides

box 26, folder 5

1975 October 22: Chemistry Colloquium, Department of Chemistry. Purdue University

box 26, folder 6

1975 October 24: Evans Lecture. Ohio State University. Chemistry Department

box 26, folder 7

1975 October 28: Towards Self-Replicating Molecules. Texas A and M University. College of Agriculture

box 26, folder 8

1975 October 29-31: Robert A. Welch Foundation Conferences on Chemical Research. XIX Photon Chemistry

box 26, folder 9

1975 November 19: Bio-Cultural Concepts of Man

box 26, folder 10

1975 December 3-4: Discussion Colloquium on the Biology of Religion

box 26, folder 11

1976 January 25-30: Gordon Research Conference on the Biology of Aging

box 26, folder 12

1976 February 6: Lectures on Chemical Evolution. Stanford University Medical Center

box 26, folder 13

1976 February 18-24: Science and Our Expectations - Bicentennial and Beyond

Note

Contains letter by Carl Sagan (10/17/75).
box 26, folder 14

1976 March 18-19: Viking Molecular Analysis Team

box 26, folder 15

1976 April 6: Genetics Seminar, Salk Institute - Origin of Self-Replicating Material

box 26, folder 16

1976 April 9-10: Viking Project. Jet Propulsion Laboratory - Viking Flight Team Memorandum

box 26, folder 17

1976 April 19-20: Renaud Lectures. Michigan State University. Department of Biochemistry

box 26, folder 18

1976 May 3-6: Organization and Expression of the Eukaryotic Genome

box 26, folder 19

1976 June 28: Langley Colloquium Series

box 26, folder 20

1977 January 10-12: Present State of Viking Data. MIT. Department of Chemistry

box 26, folder 21

1977 January 20-22: Institute for Higher Studies Seminar - A Fifty Year View

box 26, folder 22

1977 March 3-4: United States Information Agency. Viking Science Tour

box 26, folder 23

1977 March 14: New Trends in Geriatric Care. UC San Diego, School of Medicine

box 26, folder 24

1977 April 19-20: Molecules and Evolution. International Lectures on Human, Global and Universal Problems

box 26, folder 25

1977 March 29: Origin of Self-Replicating Molecules. California State University, Los Angeles

box 26, folder 26

1977 May 16: Origins of Life Festival. University of Oregon. Institute of Molecular Biology

box 26, folder 27

1977 June 28-29: Viking Science Steering Group Meeting

box 26, folder 28

1977 July 15-16: Current Biological Problems - A School for Physical Scientists

box 26, folder 29

1977 August 21 - September 3: International Summer School on Genome Organization and Function

box 26, folder 30

1977 October 17: Seminar. California Institute of Technology. Division of Biology

box 26, folder 31

1977 November 8: A Conversation About the Origins of Life

box 27, folder 1

1977 November 16: Seminar Series. California State University, Long Beach. Department of Chemistry

box 27, folder 2

1977 December 1: Science Seminar. San Diego City College. Department of Chemistry

box 27, folder 3

1978 December 6-7: Meeting of the Royal Society

box 27, folder 4

1979 August 26-31: Conference on Selforganization in Living Systems

box 27, folder 5

1979 October 25-26: The Evolution of Life - a Public Symposium

box 27, folder 6

1980 January 17-18: Fifth Science Workshop on the Origins of Life

box 27, folder 7

1980 February 4-5: American Institute of Biological Sciences. Planetary Biology Advisory Panel

box 27, folder 8

1980 April 18: Prebiotic Chemistry - Nucleic Acids and the Origin of Self-Replication

box 27, folder 9

1980 April 24-25: Science Workshops on the Origins of Life

box 27, folder 10

1980 May 20-21: Monsanto Company Technical Management Conference - New Technology Horizons

box 27, folder 11

1980 June 16-17: Workshop on Molecular Evolution and Function of Three Dimensional Structure in Nucleic..

box 27, folder 12

1980 June 23-27: International Society for the Study of the Origins of Life Conference

box 27, folder 13

1980 September 25: Pomona College Dreyfus Seminar Series

box 27, folder 14

1980 September 30: Seminar. Massachusetts Institute of Technology

box 27, folder 15

1981 February 28: Cal Tech Centennial Symposium - The Chemical Bond Structure and Dynamics

box 27, folder 16

1981 March 4: Towards an RNA Polymerase Model

box 27, folder 17

1981 March 31: Contemporary Issues Undergraduate Seminar. Origins of Life in the Ocean? Held at UCSD

box 27, folder 18

1981 June 22-24: Genome Evolution and Phenotype Variation. Cambridge Genome Meeting

box 27, folder 19

1981 July 12-15: Dalhousie Symposium on the Evolution of the Eukaryotic Genome and Its Components

box 27, folder 20

1981 August 3-4: Organizing and Planning Meeting for Workshops on Exobiology in the Exploration..

box 27, folder 21

1981 September 1-6: European Molecular Biology Organization Workshop on Accuracy

box 27, folder 22

1981 September 6-9: Max Planck Institute

box 27, folder 23

1981 October 24-25: California Catalysis Society Fall Meeting

box 27, folder 24

1981 December 7-8: Committee on Planetary Biology and Chemical Evolution - Space Science Board

box 27, folder 25

1981 December 9-11: Workshop on Exobiology in Solar System Exploration

box 27, folder 26

1982 February 2: City of Hope Research Institute Seminar

box 27, folder 27

1982 February 8-12: Gordon Conference on Metals in Biology

box 27, folder 28

1982 March 16: Biophysical/Physical Chemistry Seminar. U.C. Berkeley. Chemistry Department

box 27, folder 29

1982 March 20: Life Sciences Advisory Committee Meeting. Exobiology Program Review

box 27, folder 30

1982 March 25-28: Space Science Board. Committee on Planetary Biology and Chemical Evolution

box 27, folder 31

1982 April 12: Exobiology Program Review

box 27, folder 32

1982 April 28: Origin and Evolution of Life. Tufts University. Sackler School of Graduate Biomedical Sciences

box 27, folder 33

1982 May 17-June 3: Committee on Space Science Research, 24th Plenary Meeting. Chemical Evolution..

box 28, folder 1

1982 June 27-July 2: Darwin Centenary Conference

box 28, folder 2

1982 July 19-23: Gordon Conference on the Origin of Life

box 28, folder 3

1982 August 2-4: First Symposium on Chemical Evolution and the Origin and Evolution of Life

box 28, folder 4

1982 August 26-September 1: The Past, Present and Future of Genetics

box 28, folder 5

1982 September 5-10: Nobel Symposium on Inorganic Biochemistry

box 28, folder 6

1982 December 10-12: U.S. -Japan Cooperative Seminar on Pathogenic Mechanisms in Werner's Syndrome..

box 28, folder 7

1983 February 22: Gerontology Research Center Seminar. A Non-Enzymatic RNA Polymerase Model

box 28, folder 8

1983 February 23-25: Space Science Board. Committee on Planetary Biology

box 28, folder 9

1983 May 26-31: American Association for the Advancement of Science. Science and Engineering - Toward a..

box 28, folder 10

1983 July 10-15: 7th International Conference on the Origins of Life and 4th Meeting of the International..

box 28, folder 11

1983 August 25-26: Third Workshop on Exobiology in Solar System Exploration

box 28, folder 12

1983 September 19-20: Conference on Biomaterials

box 28, folder 13

1983 October 14: Attempts to Imitate RNA Polymerase. University of Southern California

box 28, folder 14

1983 October 18: Attempts to Develop a Nonenzymatic RNA Polymerase. California State University, Los Angeles

box 28, folder 15

1983 October 26-28: Pacific Conference on Chemistry and Spectroscopy. Origin of Life Symposium

box 28, folder 16

1985 February 7: Organization, Replication and Evolution of Early Macromolecules

box 28, folder 17

1985 February 13: Chemische Gesellschaft Zurich

box 28, folder 18

1985 April 12: City of Hope

box 28, folder 19

1985 May 2-4: Discussion on Primary Structure Conformation and Evolution of Nucleic Acids and..

box 28, folder 20

1985 June 4-8: Fourth Conversation in the Discipline. Biomolecular Stereodynamics. State Univ. of New York

box 28, folder 21

1985 July 23-26: 2nd Symposium on Chemical Evolution and the Origin and Evolution of Life

box 28, folder 22

1985 October 4-7: Niels Bohr Centenary Symposium

box 28, folder 23

1985 October 14-15: Symposium on the Origin of Life

Note

Contains photograph of birthday cake, "70 Happy Birthday Norm 70."
box 28, folder 24

1985 November 12: Seminar Program. Univ. of California, Davis. Department of Zoology

box 28, folder 25

1985 November 22-26: Annual Meeting of the Gerontology Society of America. Symposium

box 28, folder 26

1986 May 15: 50th Anniversary Symposium. A Molecular View of Evolution

box 28, folder 27

1987 January 18-30: 22nd Winter Seminar on Molecules, Information and Memory

box 28, folder 28

1987 February 17: Biochemistry Department Lecture Series. University of California, Berkeley

box 28, folder 29

1987 March 4-7: Western Winter Workshop on the Evolution of Genes and Genomes

box 28, folder 30

1987 April 28: General Biology Seminar. California Institute of Technology. Division of Biology

box 28, folder 31

1987 May 4: Significance of Chemical Templates in Studies on the Origin of Life. University of Toledo

box 28, folder 32

1987 May 27-June 3: Cold Spring Harbor. Evolution of Catalytic Function

Note

Includes letter by James Watson, 10/11/86.
box 29, folder 1

1987 June 18-19: Symposium on the Bioorganic Chemistry of Enzymes and Nucleic Acids

box 29, folder 2

1987 June 21-26: Space Life Sciences Symposium. Three Decades of Life Science Research in Space

box 29, folder 3

1987 August 17-21: Gordon Conference on the Origins of Life

box 29, folder 4

1987 September 21-25: Artificial Life - an Interdisciplinary Workshop on the Synthesis and Simulation..

box 29, folder 5

1987 November 19-26: The Frontiers of Tomorrow in Biology

box 29, folder 6

1988 January 14-15: Gunter Sachs Postdoctoral Winter Symposium. Genes and Development

box 29, folder 7

1988 February 12-14: American Academy of Sciences

box 29, folder 8

1988 April 14-15: Royal Netherlands Chemical Society. Biennial Symposium of the Organic Division

box 29, folder 9

1988 April 22: 9th Annual D.G. Davis Memorial Lecture. Molecular Replication and the Origin of Life

box 29, folder 10

1988 July 4-8: Gordon Conference on Enzymes, Coenzymes and Metabolic Pathways

box 29, folder 11

1988 September 1-10: International Summer School on Organization and Function of the Eukaryotic Genome

box 29, folder 12

1988 September 25-30: 196th American Chemical Society Meeting and Exposition

box 29, folder 13

1988 October 24: Template-Directed Synthesis of Oligonucleotides. University of California, Santa Cruz

box 29, folder 14

1989 March 27-31: Applied Molecular Evolution and the Maturation of the Immune Response

box 29, folder 15

1989 April 16-19: Ida Bean Visiting Professor Lecture Series. University of Iowa

box 29, folder 16

1989 May 8-11: Storer Life Sciences Symposium. Evolution of the Biosphere

box 29, folder 17

1989 May 17-21: Cold Spring Harbor RNA Processing Meeting

box 29, folder 18

1989 July 3-8: 6th Intl. Society for the Study of the Origin of Life Meeting and 9th Intl. Conference on the..

box 29, folder 19

1990 January 21-26: 25th Winter Seminar on Molecules, Information and Memory

box 29, folder 20

1990 February 4-8: Frontiers in Biomedical Research

box 29, folder 21

1990 February 9: Lecture Series on Frontiers in Chemistry. Research Institute of Scripps Clinic

box 29, folder 22

1990 March 5: Juan March Foundation Lectures on Molecular Biology

box 29, folder 23

1990 March 28: Biology Department Seminar. Yale University

box 29, folder 24

1990 July 15-18: Molecular Biology and the Origin of Life Symposium

box 29, folder 25

1990 July 24-27: 4th Symposium on Chemical Evolution and the Origin and Evolution of Life

box 30, folder 1

1990 October 21-24: Catalytic RNA as an Anti-HIV Agent. Design and Delivery to Cells

box 30, folder 2

1990 November 19: Structural Biology Seminar. University of California, Berkeley. Chemistry Department

box 30, folder 3

1991 February 2-8: Keystone Symposia on Molecular and Cellular Biology

box 30, folder 4

1991 February 28: Tribute to Linus Pauling on His 90th Birthday

box 30, folder 5

1991 April 22: Evolution

box 30, folder 6

1991 May 18: Bruno Zimm Symposium. University of California, San Diego

box 30, folder 7

1991 May 29: American Chemical Society, San Diego Section

 

SUBJECT FILES

box 30, folder 8

Aging. Book on Aging - Clonal Aging

box 30, folder 9

Aging. Book on Aging - Drafts

box 30, folder 10

Aging. Correspondence - 1970, 1972

box 30, folder 11

Aging. Correspondence - 1973

box 30, folder 12

Aging. Correspondence - 1974

Note

Contains letter by Jacob Bronowski, 5/8/1974
box 30, folder 13

Aging. Correspondence - 1975

box 30, folder 14

Aging. Correspondence - 1976-1981

box 31, folder 1

Aging. Correspondence - 1984

box 31, folder 2

Aging. Correspondence with publishers - 1973-1976

box 31, folder 3

Aging. Grant. Draft application to Fritz B. Burns Foundation, 1983

box 31, folder 4

Aging. Grant. McConnell-Clark Foundation grant, 1974-1975

box 31, folder 5

Aging. Grant. National Institute of Health grant - 1972-1973, refused

box 31, folder 6

Aging. Salk Institute. Research programs in aging, 1973

box 31, folder 7

Aging. Salk Institute. Workshops and symposium on aging research - 1973-1974

box 31, folder 8

Biebricher, Christof, 1972-1976

box 31, folder 9

Griffith, John Stanley, 1969. Correspondence regarding candidature for the Royal Society

box 31, folder 10

Mars photographs

box 31, folder 11

Mulliken, Robert S., 1978-1985

box 31, folder 12

RNA sequencing. Reel-to-reel audiorecording

box 31, folder 13

RNATIECLUB book materials

Note

Includes correspondence (1953-1962) from George Gamow to James Watson and Alexander Rich. Also includes a detailed table of contents.
box 31, folder 14

Sagan, Carl, 1991. Correspondence regarding Sagan's nomination to the National Academy of Sciences

box 32, folder 1

University of California, San Diego. Chemistry Department

 

SALK INSTITUTE

 

Chemical Evolution Laboratory

box 32, folder 2

Chemical Evolution Laboratory - Annual Report, 1975

box 32, folder 3

Chemical Evolution Laboratory - Annual Report, 1976

box 32, folder 4

Chemical Evolution Laboratory - Annual Scientific Reports, 1977-1980

 

Faculty

box 32, folder 5

Faculty Meetings, 1984-1986

box 32, folder 6

Senior Resident Faculty Meetings, 1976-1982

 

Fellows

box 32, folder 7

Annual Report of the Director to the Fellows, 1971

box 32, folder 8

Annual Report of the Director to the Fellows, 1975

box 32, folder 9

Fellows Committee, 1970

box 32, folder 10

Operating Committee - Meeting minutes, 1970

box 33, folder 1

Resident Members of the Committee of Fellows - Meeting minutes, 1965

box 33, folder 2

Space Committee, 1977

 

General

box 33, folder 3

Sloan Grant, 1970

box 33, folder 4

Report of Laboratory and Research Activities, 1975

box 33, folder 5

Report of Laboratory and Research Activities, 1977

box 33, folder 6

Report on Laboratory Staffing and Publications, 1976

 

Salk Memoranda

box 33, folder 7

Bronowski, Jacob, 1967-1974

box 34, folder 1

De Hoffman, Frederic, 1970-1971

box 34, folder 2

De Hoffman, Frederic, 1972

box 34, folder 3

De Hoffman, Frederic, 1973-1977

box 34, folder 4

De Hoffman, Frederic, 1978-1980

box 34, folder 5

De Hoffman, Frederic, 1981

box 34, folder 6

De Hoffman, Frederic, 1982

box 34, folder 7

Lennox, Edwin L., 1965-1974

box 34, folder 8

Salk Business, 1965-1971

box 35, folder 1

Salk Business, 1972-1975

 

Salk Institute Biotechnology/Industrial Associates

box 35, folder 2

Consultant Nonstatutory Stock Option Agreement

box 35, folder 3

SIBIA, 1981

box 35, folder 4

SIBIA, 1982

box 35, folder 5

SIBIA, 1983

box 35, folder 6

SIBIA, 1984

box 35, folder 7

SIBIA, 1985

box 35, folder 8

SIBIA, 1986

box 36, folder 1

SIBIA, 1987

box 36, folder 2

SIBIA, 1988

 

REFEREE REPORTS

box 37, folder 1

BIOCHIMICA ET BIOPHYSICA ACTA 1970 - 1973

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box 37, folder 2

BIOCHIMICA ET BIOPHYSICA ACTA 1974 - 1977

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box 37, folder 3

BIOINORGANIC CHEMISTRY 1969 - 1978

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box 37, folder 4

General 1973

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box 37, folder 5

General 1974 - 1975

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box 37, folder 6

General 1976

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box 37, folder 7

General 1977

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box 37, folder 8

General 1978

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box 38, folder 1

General 1979

Note

January - April.

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box 38, folder 2

General 1979

Note

May-December.

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box 38, folder 3

General 1980

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box 38, folder 4

General 1981

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box 38, folder 5

JOURNAL OF MOLECULAR EVOLUTION 1969 - 1978

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box 38, folder 6

JOURNAL OF MOLECULAR EVOLUTION 1979

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box 38, folder 7

JOURNAL OF MOLECULAR EVOLUTION 1980 - 1981

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box 38, folder 8

JOURNAL OF THEORETICAL BIOLOGY 1973 - 1974

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box 38, folder 9

JOURNAL OF THEORETICAL BIOLOGY 1975

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box 38, folder 10

JOURNAL OF THEORETICAL BIOLOGY 1976 - 1977

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box 38, folder 11

JOURNAL OF THEORETICAL BIOLOGY 1985 - 1987

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box 39, folder 1

JOURNAL OF THEORETICAL BIOLOGY 1988

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box 39, folder 2

JOURNAL OF THEORETICAL BIOLOGY 1989

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box 39, folder 3

JOURNAL OF THEORETICAL BIOLOGY 1990

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box 39, folder 4

JOURNAL OF THEORETICAL BIOLOGY 1991

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box 39, folder 5

National Science Foundation 1973 - 1977

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box 39, folder 6

National Science Foundation 1978

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box 39, folder 7

National Science Foundation 1979

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box 39, folder 8

National Science Foundation 1980

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