Contains the records of the Radiologic Imaging Laboratory (RIL) of the University of California, San Francisco (UCSF) from
its initial funding by Pfizer, Inc. through its operation as a unit of Diasonics, Inc. and Toshiba America MRI (TAMI). Material
relates to the RIL's development and sale of magnetic resonance imaging (MRI) technology, dated 1963-2000.
Radiologic Imaging Laboratory History: In 1975, the UCSF Department of Radiology, under the direction of Alexander Margulis, founded a small research and development
group to investigate new medical diagnostic imaging instruments and procedures. The team included electrical engineers, radiofrequency
coil experts, computer scientists, and medical researchers. They sought in part to create a clinically viable diagnostic tool
using nuclear magnetic resonance imaging, later called magnetic resonance imaging (MRI). They focused on creating a machine
capable of safely and effectively capturing scanned images of the living human body. In 1978 the lab, now called the Radiologic
Imaging Laboratory (RIL), opened an off-campus facility at 400 Grandview Drive in the Cabot, Cabot and Forbes Industrial Park
in South San Francisco. Leon Kaufman served as chief scientist and director and Lawrence Crooks served as assistant director
and electrical engineer. RIL researchers regularly consulted with physicians to initiate patient and animal studies and better
understand how pathologies impact the imaging of tissue. They experimented with magnet technology and designed new computer
hardware and software to improve MRI machine availability, image quality, speed, and sensitivity. RIL originally received
funding from the Pfizer Corporation under an agreement with the UCSF Radiology Department. In late 1981, Pfizer discontinued
its imaging activities and Diasonics purchased the project. In 1989, Toshiba acquired RIL from Diasonics. By 1990, RIL was
partnered with Toshiba America MRI (TAMI). RIL researchers secured numerous patents and received royalties for their technology.
In the 1990s, following royalty disputes with UCSF, RIL scientist Jerome Singer (later joined by Lawrence Crooks) sued the
Regents of the University of California. The court eventually found in favor of Singer and Crooks. The RIL separated from
UCSF in the mid-1990s and ceased operation in 2001.
100 Linear Feet
(68 cartons, 10 boxes, 6 oversize boxes, 3 flat file drawers)
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Collection is open for research. The UCSF Archives and Special Collections policy places access restrictions on material with
privacy issues for a specific time period. Restrictions are noted at the series level. This collection will be reviewed for
sensitive content upon request. Contact the UCSF Archivist for information on access to these files.