Guide to the Douglas L. Brutlag Papers

Stanford University Libraries Department of Special Collections and University Archives
Stanford, California
October 2010
Copyright © 2011 The Board of Trustees of Stanford University. All rights reserved.

Note

This encoded finding aid is compliant with Stanford EAD Best Practice Guidelines, Version 1.0.


Overview

Call Number: SC0651
Creator: Brutlag, Douglas L.
Title: Douglas L. Brutlag papers
Dates: 1968-1999
Physical Description: 18 linear feet (19 boxes)
Summary: The papers document Brutlag's research and teaching in biochemistry and his work in bioinformatics. The papers include research notebooks, 1972-1982 and undated, some of which were compiled by Denise Lew and Bruce Moseley; class syllabi, exams, problem sets, and Brutlag's notes and lecture outlines, 1968-1980; and papers pertaining to bioinformatics, 1981-1999, which include correspondence, articles, memoranda, proposals, reports, and computer software documents.
Language(s): The materials are in English.
Repository: Department of Special Collections and University Archives
Stanford University Libraries
557 Escondido Mall
Stanford, CA 94305-6064
Email: speccollref@stanford.edu
Phone: (650) 725-1022
URL: http://www-sul.stanford.edu/depts/spc/spc.html

Administrative Information

Provenance

The papers were given to the Stanford University Archives by Douglas L. Brutlag in 2002.

Information about Access

This collection is open for research; materials must be requested at least 48 hours in advance of intended use.

Ownership & Copyright

All requests to reproduce, publish, quote from, or otherwise use collection materials must be submitted in writing to the Head of Special Collections and University Archives, Stanford University Libraries, Stanford, California 94304-6064. Consent is given on behalf of Special Collections as the owner of the physical items and is not intended to include or imply permission from the copyright owner. Such permission must be obtained from the copyright owner, heir(s) or assigns. See: http://library.stanford.edu/depts/spc/pubserv/permissions.html.
Restrictions also apply to digital representations of the original materials. Use of digital files is restricted to research and educational purposes.

Cite As

[Identification of item], Douglas L. Brutlag Papers (SC0651). Department of Special Collections and University Archives, Stanford University Libraries, Stanford, Calif.

Alternative Formats

At one time, scanned copies of most of these documents could be found at http://hrst.mit.edu/hrs/bioinformatics/public/Documents.htm under "Brutlag-Friedland-IntelliGenetics Collection." As of 2009, researchers are directed to contact Tim Lenoir (Lenoir@duke.edu).

Biographical/Historical Sketch

Douglas L. Brutlag earned his B.S. in biology at the California Institute of Technology in 1968, and his Ph.D. in biochemistry at Stanford in 1972. He joined the Stanford faculty in 1974 as an assistant professor of biochemistry, becoming a tenured associate professor in 1980. Brutlag's work bridges the fields of biology and computer sciences, in the rapidly expanding field of bioinformatics. Brutlag is a cofounder of IntelliCorp and IntelliGenetics Inc., served on the Scientific Advisory Board (Chairman) of Time Logic Inc., and is Director of the Bioinformatics Resource at Stanford University.

Description of the Collection

The papers document Brutlag's research and teaching in biochemistry and his work in bioinformatics. The papers include research notebooks, 1972-1982 and undated, some of which were compiled by Denise Lew and Bruce Moseley; class syllabi, exams, problem sets, and Brutlag's notes and lecture outlines, 1968-1980; and papers pertaining to bioinformatics, 1981-1999, which include correspondence, articles, memoranda, proposals, reports, and computer software documents.

Access Terms

Brutlag, Douglas L.
Lew, Denise.
Moseley, Bruce.
Stanford University--Faculty.
Biochemistry--Study and teaching.
Bioinformatics
DNA--Biosynthesis.
DNA Replication.
Molecular biology--Data processing


Collection Contents

Box 1

Binder with Research Notes, Books I and II, pp. 1-332 (with index)

Box 1

Binder with Research Notes, Books III and IV, pp. 333-667 (with index)

Box 1

Binder with Research Notes, Books V and VI, pp. 668-933 (with index)

Box 1

Binder with Research Notes, Books VII and VIII, pp. 934-1218 (with index)

Box 2

Binder with Research Notes, Books IX and X, pp. 1219-1553 (with index)

Box 2

Binder with Research Notes, Books XI and XII, pp. 1554-2077 (with index)

Box 2

Binder with Research Notes, I and II, pp. 1-342 (with index)

Box 2

Binder with Research Notes, III and IV, pp. 343-670 (with index)

Box 3

Binder with Research Notes, V and VI, pp. 671-986 (with index)

Box 3

Binder with Research Notes, VII and VIII, pp. 987-1280 (with index)

Box 3

Binder with Research Notes, IX and X, pp. 1281-1515 (with index)

Box 3

Binder with Research Notes, XI, pp. 1516-end (no index)

Box 4

Binder with Research Notes, I and II, pp. 1-155 (with index)

Box 4

Unlabelled binder 1972-73, pp. 1-188 and 1-48 (with index)

Box 4

Biochemistry 201/102 - problem sets, exams, etc. 1968-1974

Box 5

Research Notebook (with index) 1974 Dec-1975 Dec

Box 5

Research Notebook (with index) 1976 Jan-Dec

Box 5

Research Notebook (with index) 1977 Feb-Dec

Box 5

Research Notebook (with index) 1977 Oct-1978 Aug

Box 6

Research Notebook (with index) 1978 Sep-1979 Feb

Box 6

Research notebook by Denise Lew, Satellite DNA (with index) 1980-1982 Feb

Box 6

Research notebook by Denise Lew, Topoisomerase I (with index) 1980 Jun-1981 Dec

Box 6

Research notebook by Denise Lew, Topoisomerase II (with index) 1982 Jan-Jul

Box 6

Binder of research notes, II, pp. 156-161 and unnumbered pages (no index) 1977 Jan-1978 Jun

Box 7

Research notebook by Denise Lew, Satellite DNA (with index) 1979 Jul-1980 May

Box 7

Research notebook, Satellite sequences, mostly computer printouts (no index)

Box 7

Research notebook, Sequence Analysis I, computer printouts (no index)

Box 7

Research notebook, Sequence Analysis II, computer printouts (no index)

Scope and Content Note

Also includes "Nucleic Acid Computer Program Explanatory Manual" by Lawrence Jay Korn, Cary L. Queen, and Mark N. Wegman.
Box 8

Research notebook, Bruce Moseley, Satellite DNA Isolation (with index) 1975 Jul-Sep

Box 8

Research notebooks, Bruce Moseley, Satellite Isolation and Chromatin Studies, 1976 summer; In Situ hybridization (with index), 1977 summer

Box 8

Research notebook, In Situ (with index) 1979 Jan-1980 May

Box 8

Research notebook, In Situ (with index) 1977 Nov-1978 Dec

Box 8

Research notebook, Nick Translation, DNA on filter, Filter hybrid (no index) 1978-1979

Box 8

Research notebook, unlabeled pp. 2078-2145 (no index) with copy of index for pp. 1-1902

Box 8

Research (notes and computer printouts, no index)

Box 8

Notebook, Physical Properties (reference lists, not research notes, no index)

Box 8

Notebook, California Institute of Technology, Biophysics of Macromolecules (Bi/Ch 132a) - lab notes (includes class problem sets)

Box 8

Notebook, Methods (two copies) - directions for DNA work

Box 9

Class materials, binder for Stanford University School of Medicine, Biochemistry 101, Autumn 1968, and Biochemistry 102, Winter 1968/69 - notes, lecture outlines

Box 9

Class materials, binder for California Institute of Technology, Division of Biology, Bi107, Autumn 1966, Bi107b, Winter 1967, Bi107c, Spring 1967, Bi110, Winter 1968 - notes, etc.

Box 9

Class materials, notebook for seminars - papers, etc. 1979-1980

Box 9

EMBL/NIH Workshop "Future Databases for Molecular Biology" at EMBL, Heidelberg February 1987 - conference materials, papers, notes

Box 10, Folder 1

CLUSTAL, 1988-1989

Box 10, Folder 2

Product Review Board (PRB) 1987-1990

Box 10, Folder 3

National Library of Medicine (NLM) - Law 1987-1993

Box 10, Folder 4

StrateGene 1988

Box 10, Folder 5

SpeedReader 1989-1990

Box 10, Folder 6

PEPPER (1) 1987-1988

Box 10, Folder 7

PEPPER (2) 1986-1988

Box 10, Folder 8

Multisequence Alignment Project 1986-1987

Box 11, Folder 1

BLAZE User Manual 1992

Box 11, Folder 2

BLAZE 1991-1995

Box 11, Folder 3

BLAZE-MPsrch Folder 1993-1994

Box 11, Folder 4

MPsrch 1990-1993

Box 11, Folder 5

BLAZE-MasPar 1992-1993

Box 12, Folder 1

DAP (Distributed Array of Processors) 1988-1992

Box 12, Folder 2

Merge 2.0 - Merge II Description

Box 12, Folder 3

Database Searcher 1991

Box 12, Folder 4

Amoco Research Proposal 1990-1992

Box 12, Folder 5

FastDB 1988-1991

Box 12, Folder 6

FastDB Paper

Box 12, Folder 7

IntelliGenetics Suite (IG Suite) 1987-1992

Box 13, Folder 1

ReQuest 1988-1992

Box 13, Folder 2

IntelliGenetics, Inc. 1981-1991

Box 13, Folder 3

Securities and Exchange Commission (SEC) / Stock Documents 1983-1984

Box 13, Folder 4

GenBank 1987-1994

Box 13, Folder 5

DataGene Proposal 1986-1988

Box 13, Folder 6

PC/Gene 1989-1992

Box 14, Folder 1

Redbook 1988-1990

Box 14, Folder 23

Search/Test results on various databases, MPsrch 1994

Box 14, Folder 4

Mercury 1992-1993

Box 14, Folder 5

D. Naor and D. Brutlag manuscript, "On Near-Optimal Alignments of Biological Sequences" (two copies) 1994 Jul

Box 14, Folder 6

Genetics Computer Group (GCG) 1987-1988

Box 15, Folder 1

BIONET (1) 1983-1987

Box 15, Folder 2

BIONET (2) 1987-1992

Box 15, Folder 3

BIONET (3) 1997-1988

Box 15, Folder 4

BIONET (4) 1984-1988

Box 15, Folder 5

BIONET Meetings 1984-1989

Box 16

BIONET Training Manual, TOPS-20 Version 4.0 1984

Box 16

Binder with BIONET slides

Box 16

IntelliGenetics binder with slides

Box 17, Folder 1

Automap 1988

Box 17, Folder 2

ARIAS 1985-1991

Box 17, Folder 3

SEQ 1981-1982

Box 17, Folder 4

ASAP (Automatic Sequence Assembly Program) 1988-1992

Box 17, Folder 5

U.S.P.T.O (U.S. Patent and Trademark Office) 1993

Box 17, Folder 6

Miscellaneous Documents 1982-1987

Box 17, Folder 7

Miscellaneous notes

Box 18, Folder 1

FDF - TRW 1985-1987

Box 18, Folder 2

IntelliCorp 1983-1989

Box 18, Folder 3

Graphics Spec 1982

Box 18, Folder 4

National Library of Medicine (NLM) / NIH 1986-1999

Box 19

Folder of miscellaneous records 1978-1989

Scope and Content Note

Includes faculty minutes and Biochemistry System Proposal by Tito E. Gervacio.
Box 19

Monthly financial reports 1970s-1999

Box 19

Miscellaneous files on products and X/Gene software

Box 19

1 jaz disk labeled "Intelligenetics"

Box 19

Copy of Brutlag's Stanford University dissertation: "Enzymatic mechanisms in DNA replication" 1972