Container List
Correspondence and Subject Files.
1990-2005.
Scope and Content
The Correspondence and Subject Files series contains letters and copies of electronic mail between Klein and his academic
and professional colleagues, corporations, editorial boards, publishers and professional organizations. Klein's correspondence
details conversations related to his research interests, publications and studies. Klein also interfiled subject files with
his correspondence which remain arranged in their original order. The subject files include topics such as agoraphobia scale,
bioethics, carbon monoxide study, clinical trials, Detroit Project, Freud rhetoric, New York Times, patents, Post controversy,
psychotherapy, scientific misconduct, serotonin, thyroid and valproate. This series is organized alphabetically by correspondent
or subject.
Box 1
A-Aw.
Scope and Content Note
Correspondents include Dominick Abel, Association for Clinical Psychosocial Research (ACPR), Anxiety Disorders Association
of America (ADAA), Vito Agosti, Agency for Health Care Policy and Research (AHCPR), Nancy C. Andreasen, David Antonuccio,
American Psychiatric Association (APA), Archives of General Psychiatry and American Society of Clinical Psychopharmacology
(ASCP).
Box 2
B-Bu.
Scope and Content Note
Correspondents include James C. Ballenger, Jack D. Barchas, David Barlow, Marco Battaglia, Maria Isabel Behrens, Nancy Berezin,
Floyd Bloom, Naomi Breslau, Gerald Bruder, David Burns and Hester Butterfield.
Box 3
C-Cop.
Scope and Content Note
Correspondents include Anne Cameron, Bernard J. Carroll, Giovanni B. Cassano, Steve Chan, Tim Chapman, Ciba-Geigy, Collegium
Internationale Neuro-Psychopharmacologicum (CINP), David C. Clark, Lee S. Cohen, Pat Cohen, Joseph Collins, Tom Cooper and
Jeremy Coplan.
Box 4
Cor-Det.
Scope and Content Note
Correspondents include Alicia Courad, James Coyne, Clinical Research Centers (CRC), Timothy Crowe, Current Medicine (CM),
Jay B. Cutler, Antonio Damasio, Karina Davidson, Robert Davies and Sharon Davies.
Box 5
Det-Elk.
Scope and Content Note
Correspondents include Douglas Sutherland Dodge, Bruce Dohrenwend, Regina Dolan-Sewell, Steve Donovan, Electronic Journal
of Treatment Research and Irene Elkin.
Box 6
Elk-Fis.
Scope and Content Note
Correspondents include Irene Elkin, Jean Endicott, Tanya Fabian, Janet Fairbanks, Brian Fallon, Jan Fawcett, Max Fink, Gerald
Fishbach, Bernard Fisher and Mark Fisher.
Box 7
Fis-Fye.
Scope and Content Note
Correspondents include Mark Fisher, Edna Foa, Patrick L. Furlong and Abby Fyer.
Box 8
Fye-Gua.
Scope and Content Note
Correspondents include Abby Fyer, Glen O. Gabbard, Amir Garakani, Robin Garfinkel, Louis Gates, Conrad Gilliam, Christian
Gillin, Sandy Glassman, Ira Glick, Ray Goetz, Gary Goldsmith, Frederick K. Goodwin, James D. Goodwin, Jack Gorman, Steve Greenwald,
Charles Grudzinskas and Mary Guardino.
Box 9
Gut-Isl.
Scope and Content Note
Correspondents include Lee Guthrie, Wilma Harrison, Orrin J. Hatch, Bob Hirschfield, Rudolph Hoehn Saric, Florian Holsboer,
Philip S. Holzman, Steven Hyman, Sonia Iapichino and Interneuron Pharmaceuticals Incorporated.
Box 10
J-Kle.
Scope and Content Note
Correspondents include Janssen Pharmaceutica Incorporated, Janus Pharmaceuticals Incorporated, Jeffrey G. Johnson, Lewis L.
Judd, David Kahn, Mirjam Kampman, Eric Kandel, John Kane, Byram Karasu, Fred Kass, David Katerndahl, Roger G. Kathol, Wayne
Katon, Kenneth Kendler, Thomas G. Keens, Hilary Klein an Rachel Klein.
Box 11
Kle-Lie.
Scope and Content Note
Correspondents include Jim Knowles, Ken Kobak, Helena C. Kraemer, David J. Kupfer, Matt G. Kushner, Cindy Lah, Donald Landry,
David Lane, Louis C. Lasagna, Eugene Laska, Philip W. Lavori, Seth Lederman, Barbara J. Leibowitz, Bill Leissner, Stefan Lerner,
Alan I. Leshner, Andrew Levin and Michael R. Liebowitz. Materials also include one folder of Klein's "Notes to Self."
Box 12
Lie-Man.
Scope and Content Note
Correspondents include Michael Liebowitz, Scott Lilienfeld, Josh Lipsitz, Bruce Lydiard, Dean F. MacKinnon, Dolores Malaspina,
Gael Malleret, Manic Depressive Association and John Mann.
Box 13
Man-Naf.
Scope and Content Note
Correspondents include Sal Mannuzza, Isaac Marks, Randall Marshall, Jose Martinez, Jack D. Maser, Sanjay Mathew, Richard Mayeux,
Una McCann, Pat McGrath, Paul Meehl, Herbert Meltzer, Roger Meyer, MIT Press, Stuart Montgomery, Mood Disorders Support Group,
Frank Mucha, Lilliana Mujica-Parodi and National Foundation For Depressive Illness, Inc (NAFDI).
Box 14
Nar-Nim.
Scope and Content Note
Correspondents include National Alliance for Research on Schizophrenia and Depression (NARSAD), National Association of Science
Writers, National Foundation for Depressive Illness, Inc., National Bioethics Advisory Commission (NBAC), Charles B. Nemeroff,
National Institute on Alcohol Abuse and Alcoholism (NIAA), NIDA/VA Substance Abuse Medication Development Center and National
Institute of Mental Health (NIMH).
Box 15
Nim-Pap.
Scope and Content Note
Correspondents include NIMH, Anca Nitescu, G.R. Norton, Ned Nunes, David Nutt, John Oldham, Raphael Osheroff, Mortimer Ostow,
Oxford University Press, Jaak Panksepp, Laszlo Papp and Steven Papp.
Box 16
Par-Pri.
Scope and Content Note
Correspondents include Herbert Pardes, Morris Parloff, Michele Pergadia, Pfizer Pharmaceuticals, Harold Pincus, Dan Pine,
Ian Pitchford, Robert Pohl, Mark Pollack, Josh Pollock, Stephen W. Porges, Maurice Preter, David Preven and Public Responsibility
in Medicine and Research (PRIM&R) .
Box 17
Pro-R.
Scope and Content Note
Correspondents include Psychiatric Consultation Service, Myron L. Pulier and Fred Quitkin.
Box 18
Rab-Ros.
Scope and Content Note
Correspondents include Judith Rabkin, Stanley Rachman, Rand Corporation, Charles B. Rangel, Judith L. Rapoport, Stanley Rapaport,
Oakley Ray, Darrel Regier, Karl Rickels, Ron Rieder, Arthur Rifkin and Don Ross.
Box 19
Rus-Sch.
Scope and Content Note
Correspondents include A. John Rush, Alan Schatzberg, Frank Schneier, Franklin Schneier, Nina Schooler, Bob Schuster and Gerri
Schwartz.
Box 20
Sci-Sin.
Scope and Content Note
Correspondents include Stuart Seidman, David Shaffer, Francine Shapiro, Vera Sharav, Steven Shea, Tracy Shea, Katherine Shear,
Javaid Sheikh, Anantha Shekhar, Elinor K. Shin and Smit Sinha.
Box 21
Sin-Ste.
Scope and Content Note
Correspondents include Smit Sinha, Marcia Slattery, Lauren Smith, Jessica Sonnenschein, Robert Spitzer, Larry Stanford, Hans
Stassen, Dan Stein, Zena Stein and John W. Stewart.
Box 22
Stu-Val.
Scope and Content Note
Correspondents include Robert Stuckey, Bonnie Taylor, Michael Terman, Department of Therapeutics, Linda Timmons, Alvin Toffler,
Elaine Tricamo, Frankie Trull, Peter Tyrer and Tom Uhde.
Box 23
Vel-Wak.
Scope and Content Note
Correspondents include Veteran's Administration, VivoMetrics, Leslie Vogel and Jerome Wakefield.
Box 24
Wak-Z.
Scope and Content Note
Correspondents include James Wakefield, Jane Weaver, Myrna Weissman, Paul Wender, Phyllis Wender, Georg Wiedemann, Alison
West, Williams & Wilkins, Henny Wolland, World Psychiatric Association, Richard Wurtman, Yamanouchi Pharmaceutical Company,
Rachel Yehuda and Vikram Yeragami.
American College of Neuropsychopharmacology Committee Files.
1994-2005.
Scope and Content
The American College of Neuropsychopharmacology (ACNP) Committee Files series includes copies of Klein's records from his
involvement with this society. Materials include correspondence, reports, memoranda, drafts of ethical conduct statements,
minutes, task force and committee membership lists and copies of Klein's statements for presentations. The ACNP, founded in
1961, is a U.S. professional society in brain, behavior and psychopharmacology research for which Klein, a Life Fellow, served
as President and Chairman.
Box 25
ACNP Clinical Trials Workshop.
2005.
Box 26
ACNP Ethics Committee.
1994.
Box 26
ACNP Ethics Statement.
1994-1995.
Box 27
ACNP Ethics Statement.
1996.
Box 27
ACNP History Task Force.
1994-1997.
Box 27
ACNP Liaison Committee with Governmental Agencies and the Pharmaceutical Industry.
Box 27
ACNP Postmarketing Task Force.
2005.
Grants.
1994-2002.
Restrictions on Access
Boxes 28-32: Restricted access. Apply to Library Special Collections at least one month in advance of a research visit, so
confidential identification material may be redacted.
Boxes 28-30
Program Project Grant (Restricted).
1994-1999.
Scope and Content Note
The Program Project Grant (PPG) was funded by the National Institute of Mental Health (NIMH) beginning in 1983 and commencing
in 1999. Klein served as the principal investigator for this Psychobiology/Genetics/Treatment of Anxiety Disorders project,
a multidisciplinary, programmatic study of anxiety disorders. The project abstract explains, "The overall thrust is to both
validate and refine the nosology of anxiety disorders using familial, developmental, epidemiologic, pharmacological challenge
and molecular biologic criteria." These records include Klein's files for this project's final five years and include financial
reports, memoranda, publications, progress report summaries, employee biographical sketches, correspondence and continuation
grant applications.
- Box 28: Year 10
- Box 29: Year 11 and 12
- Box 30: Year 13 and 14
Box 31
Mental Health Clinical Research Center Grant (Restricted).
1995-1999.
Scope and Content Note
Mental Health Clinical Research Center (MHCRC) Grant was funded by the National Institute of Mental Health (NIMH) beginning
in 1978 and commencing in 1999. Klein served as the principal investigator for this project to develop a MHCRC at New York
State Psychiatric Institute (NYSPI) for the multi-disciplinary study of anxiety disorders, anxiety symptoms and related disorders.
The NIMH provided funding for 21 years. These records are Klein's files for the project's final four years and include financial
reports, memoranda, personnel reports, progress report summaries, award notices, correspondence and continuation grant applications.
Box 33, Folders 1-3, Box 32, Folder 1
Conte Centers Grant Proposal.
1998-1999.
Scope and Content Note
Memoranda, correspondence with the NIMH, and Conte Centers for the Neuroscience of Mental Disorders grant application materials
concerning Klein's project entitled, "NYSPI Conte Neuroscience Center for Panic Disorder." According to Klein, "The proposed
Center is an integrated neuroscience program aimed at deepening the current programmatic effort of the Columbia Panic Group
to understand the development and pathophysiology of childhood separation anxiety and panic disorder." Materials also include
articles by Klein and his colleagues on anxiety disorders and the significance of panic.
Box 32: Restricted access. Apply to Library Special Collections at least one month in advance of a research visit, so confidential
identification material may be redacted.
Box 32, Folders 2-4
Psychiatric Institute's Research Support Grant (Restricted).
1990-1995.
Scope and Content Note
Materials include applications for the Psychiatric Institute's Research Support Grant (PIRSG) submitted by investigators at
the New York Psychiatric Institute for limited support for pilot studies, bridging funds and other research projects relevant
to the research objectives of the Institute.
Box 33, Folders 4-6, Box 32, Folder 4
Research For Mental Hygiene, Inc. Grant.
2002.
Scope and Content Note
Klein's grant proposal for Psychobiology of IV Naloxone and Lactate in Normals project which investigates panic symptoms within
a pilot study of 12 normal subjects with the goal of understanding the pathophysiology of the hallmark attack.
Box 32: Restricted access. Apply to Library Special Collections at least one month in advance of a research visit, so confidential
identification material may be redacted.
Box 33
National Institutes of Health Grant.
2002.
Scope and Content Note
Materials include Klein's grant application entitled, "Yoga Techniques and the Treatment of Panic Disorder." According to
Klein, the overall goal of this proposed project is to determine whether a yoga-based stress reduction program can improve
the symptomatology of panic disorder.
Box 33
Interventional Research Center Grant.
1998.
Scope and Content Note
Grant proposal drafts by Klein and colleagues for a National Institute of Mental Health (NIMH) Core Grant for Enhancing Neuroscience
Translation (CoGENT). Klein, Jack Gorman and Mike Liebowitz propose an Interventional Research Center (IRC) for the Treatment
of Anxiety and Related Disorders at New York State Psychiatric Institute/Columbia University in order to investigate unresolved
issues of critical clinical importance in the treatment of anxiety disorders.
Research Projects.
circa 1960s, 1984-1985, 1995-1999.
Scope and Content
Boxes 35-39: Restricted access and use because of patient/subject names and personally identifiable information. This material
is closed until further notice, pending consultation with campus counsel about policies and procedures for access and use.
Box 34, Folders 1-4
Kirsch manuscript.
1998.
Scope and Content Note
Klein's research files on Irving Kirsch and Guy Sapirstein's article, "Listening to Prozac but Hearing Placebo: A Meta-Analysis
of Antidepressant Medication" wherein Kirsch and Sapirstein address the problem of the relation of placebo effect to drug
effect by presenting a meta-analysis of 19 double-blind placebo-controlled clinical trials. Klein critiques their conclusion
that any apparent drug effect may actually be an active placebo effect as "problematic for those that believe that antidepressant
medication has made a major contribution to the treatment of the mentally ill." Materials include Klein's correspondence,
collection of research articles, notes and drafts of response articles, "Listening to Meta-Analysis But Hearing Bias" and
"Reply to Kirsch's Rejoinder re: Antidepressant Meta-Analysis."
Box 34, Folders 5-14
Treatment of Depression Collaborative Research Program.
circa 1980s.
Scope and Content Note
The National Institute of Mental Health (NIMH) Treatment of Depression Collaborative Research Program (TDCRP) was the first
multisite coordinated study initiated by the NIMH in the field of psychotherapy research. Three research sites, using an identical
research protocol, investigated the effectiveness of two forms of brief psychotherapy (cognitive behavior therapy and interpersonal
psychotherapy) in the treatment of outpatient depression. Materials include case files, correspondence and Klein's comments
and summaries of cases which include his assessments of patient response to psychotherapy and pharmacotherapy treatment.
Boxes 35-38
Drug Therapy Studies (Restricted).
circa 1960s.
Scope and Content Note
A portion of patient files from two Drug Therapy Studies conducted at Long Island Jewish-Hillside Hospital. As a research
psychiatrist at Hillside, Klein began exploring pharmacological solutions to treating panic disorders. Klein calls the method
he devised in the early sixties at Hillside "pharmacological dissection." This led to a new method of psychiatric diagnosis
based on scientific observation rather than Freudian theories.
Files are organized alphabetically by patient's last name.
First Study: Box 35 includes files Coh-Fio and Box 36 includes files Gan-Fas. Second Study: Box 37 includes files Ber-Coh
and Box 38 includes files Dan-Fri.
Box 39
Consensus Summary SADS-LA Narratives (Restricted).
1984-1985.
Scope and Content Note
Diagnostic summaries and narratives for patients who were administered the Schedule for Affective Disorders and Schizophrenia
- Lifetime Anxiety version.
Box 40
Research articles.
Scope and Content
Scientific research articles collected by Klein or authored by Klein. Materials by Klein include "New Ideas for Testing Psychiatric
Treatments - What's Wrong and How to Fix Impaired Discovery and Fact-Poor Practice," "Dealing with the Effects of Therapy
Allegiances," "Bipolar Disorder," "Uses of MAO Inhibitors for Borderline Patients" and "Physiology and the Anxiety Disorders."
Box 41
Klein articles.
Scope and Content
Materials include articles authored by Klein and articles by Klein and colleagues such as "Efficacious and Safe Psychotropics
Not Available in the United States," "Lactate Provocation of Panic Attacks," "Evidence for Genetic Linkage Between a Polymorphism
in the Adenosine 2A Receptor and Panic Disorder" and "Harmful Dysfunction, Disorder, Disease, Illness, and Evolution." Correspondence
between Klein, colleagues and publishers is also included.
Box 42
Depression in Primary Care Site Manual.
1995.
Scope and Content
Copy of Depression in Primary Care Site Manual distributed to participants of the Care Study Investigator Meeting held in
Madison, Wisconsin.
Video and Audiotapes.
1975-1997, and undated.
Box 43
Audiotapes.
Scope and Content
Eleven audiotapes of lectures and presentations from meetings and conferences. Titles include the following: "Depressive Subtypes:Treatment
and Diagnostic Implications," "Treatment and Outcome of Major Depression," "Diagnosis and Comorbidity of Panic Disorder" and
"Anxiety, Dissociative and Somatoform Disorders."
Box 43
Videotapes.
Scope and Content
Thirty-five videotapes of presentations, interviews and talks by Klein and colleagues. Videotapes featuring Klein include
the following titles: "Anxiety and Depression: Issues in Outpatient Psychiatry," "Anxiety Disorders," "Spontaneous Panic Attacks,"
"Pharm. Treatment of Borderline Patients" and "Human Medicine Show #1."
Awards, Certificates, Nominations and Biographies.
1986-2005.
Box 44, Folder 1
Salmon Award.
1993.
Scope and Content Note
Klein received the Thomas W. Salmon Award from The New York Academy of Medicine.
Box 44, Folder 2
The American Society of Clinical Psychopharmacology, Inc. Certificate.
1994.
Scope and Content Note
This certificate attests that Klein is a member in good standing through December 31, 1994.
Box 44, Folder 3
Nominations and applications.
1986-2005.
Scope and Content Note
Nominations and applications for awards, honors and prizes.
Box 44, Folders 4-6
Biographical sketches.
Scope and Content
Brief Klein biographies used for grants, award applications and publications.
